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IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER

Product Name
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
CAS No.
39028-27-8
Chemical Name
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
Synonyms
SIA;SIA Crosslinker;NHS IODOACETATE;N-IodoacetoxysucciniMide;Succinimidyl iodoacetate;N-SUCCINIMIDYL IODOACETATE;SIA (succinimidyl iodoacetate);N-Succinimidyl Iodoacetate >N-SucciniMidyl iodoacetate(SIA);N-Succinimidyl Iodoacetate, 95+%
CBNumber
CB9364435
Molecular Formula
C6H6INO4
Formula Weight
283.02
MOL File
39028-27-8.mol
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IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Property

Melting point:
148°C
Boiling point:
315.6±44.0 °C(Predicted)
Density 
2.11±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMF: 50 mg/mL
form 
powder
color 
White to Off-White
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29251900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I9760
Product name
Iodoacetic acid N-hydroxysuccinimide ester
Purity
powder
Packaging
100mg
Price
$264
Updated
2024/03/01
Sigma-Aldrich
Product number
I9760
Product name
Iodoacetic acid N-hydroxysuccinimide ester
Purity
powder
Packaging
50mg
Price
$304
Updated
2024/03/01
TCI Chemical
Product number
S0844
Product name
N-Succinimidyl Iodoacetate
Purity
>95.0%(N)
Packaging
100mg
Price
$235
Updated
2024/03/01
TRC
Product number
S690290
Product name
N-Succinimidyl Iodoacetate
Packaging
50mg
Price
$80
Updated
2021/12/16
Chem-Impex
Product number
22998
Product name
Succinimidyliodoacetate,≥98%(HPLC)
Purity
≥98%(HPLC)
Packaging
250MG
Price
$122.3
Updated
2021/12/16
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IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Chemical Properties,Usage,Production

Description

SIA Crosslinker is a non-cleavable, water-soluble crosslinker containig an NHS ester and an iodine group. The NHS ester is reactive toward amines while the iodine reacts with thiol groups.

Chemical Properties

White Solid

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 1.5 Angstroms

Uses

forms water soluble carboxylate derivatives

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 1.5 Angstroms

Biological Activity

SIA Crosslinker is a non-cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Suppliers

Wuhan Brin Technology Co., Ltd.
Tel
3456065315 13260619011
Email
3456065315@qq.com
Country
China
ProdList
1958
Advantage
58
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376090521
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
979
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Suzhou Highfine Biotech Co., Ltd
Tel
0512-68311833 13962195826
Fax
0512-68417696
Email
wuhao@highfine.com
Country
China
ProdList
499
Advantage
75
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER 39028-27-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER 39028-27-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Career Henan Chemical Co
Product
IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER 39028-27-8
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2019-12-26

39028-27-8, IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTERRelated Search:


  • N-HydroxysucciniMide Iodoacetic Acid Ester
  • N-IodoacetoxysucciniMide
  • Iodoacetic Acid N-Succinimidyl Ester N-(Iodoacetoxy)succinimide
  • 2,5-Pyrrolidinedione, 1-[(iodoacetyl)oxy]-
  • N-SucciniMidyl iodoacetate(SIA)
  • SIA
  • N-HYDROXYSUCCINIMIDYL IODOACETATE
  • NHS IODOACETATE
  • N-SUCCINIMIDYL IODOACETATE
  • SIA Crosslinker
  • Iodoacetic acid N-hydroxysuccinimide ester powder
  • 2,5-Dioxopyrrolidin-1-yl 2-iodoacetate
  • IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
  • Succinimidyl iodoacetate
  • SIA (succinimidyl iodoacetate)
  • 2-Iodoacetate N-Succinimidyl Ester
  • N-Succinimidyl Iodoacetate &gt
  • Acetic acid, 2-iodo-, 2,5-dioxo-1-pyrrolidinyl ester
  • Iodoacetic Acid N-Succinimidyl Ester
  • N-Succinimidyl Iodoacetate, 95+%
  • 39028-27-8
  • C6H6INO4
  • C6H6NO4I
  • BioChemical
  • Crosslinking
  • Heterobifunctional Cross-Linking Reagents
  • Proteomics and Protein Expression
  • Protein Modification
  • Proteomics
  • MTS and Sulfhydryl Active Reagents
  • Heterobifunctional Crosslinker
  • heteroXlink
  • Cross Linking Reagents
  • MTS & Sulfhydryl Active Reagents
  • Active Esters/AdditivesProtein Modification
  • Active Esters/AdditivesSynthetic Reagents
  • Coupling
  • Crosslinking
  • Heterobifunctional Cross-Linking Reagents
  • Peptide Synthesis