6-BROMO-IMIDAZO[1,2-A]PYRIDIN-8-AMINE
- Product Name
- 6-BROMO-IMIDAZO[1,2-A]PYRIDIN-8-AMINE
- CAS No.
- 676371-00-9
- Chemical Name
- 6-BROMO-IMIDAZO[1,2-A]PYRIDIN-8-AMINE
- Synonyms
- 6-broMoiMidazo[1;2-a] pyridin-8-aMine;8-Amino-6-bromoimidazo[1,2-a]pyridine;6-BROMO-IMIDAZO[1,2-A]PYRIDIN-8-AMINE;6-Bromoimidazo[1,2-a]pyridin-8-ylamine;Imidazo[1,2-a]pyridin-8-amine, 6-bromo-;6-Bromo-1H-imidazo[1,2-a]pyridin-8-amine;6-bromo-1H-imidazo [1,2-a]pyridine-8-amine;6-Bromo-1,5-dihydroimidazo[1,2-a]pyridin-8-amine;6-bromoH-imidazo[1,2-a]pyridine-8-carboxylic acid
- CBNumber
- CB9371624
- Molecular Formula
- C7H6BrN3
- Formula Weight
- 212.05
- MOL File
- 676371-00-9.mol
6-BROMO-IMIDAZO[1,2-A]PYRIDIN-8-AMINE Property
- Density
- 1.87±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 6.31±0.50(Predicted)
- Appearance
- Light brown to gray Solid
- InChI
- InChI=1S/C7H6BrN3/c8-5-3-6(9)7-10-1-2-11(7)4-5/h1-4H,9H2
- InChIKey
- NBHRWSCVWCCKDN-UHFFFAOYSA-N
- SMILES
- C12=NC=CN1C=C(Br)C=C2N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B678825
- Product name
- 6-Bromo-1,5-dihydroimidazo[1,2-A]pyridin-8-amine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 070223
- Product name
- 6-Bromo-1H-imidazo[1,2-a]pyridin-8-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 3H30-9-43
- Product name
- 8-Amino-6-bromoimidazo[1,2-a]pyridine
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FB54436
- Product name
- 6-Bromoimidazo[1,2-a]pyridin-8-amine
- Packaging
- 250mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FB54436
- Product name
- 6-Bromoimidazo[1,2-a]pyridin-8-amine
- Packaging
- 500mg
- Price
- $190
- Updated
- 2021/12/16
6-BROMO-IMIDAZO[1,2-A]PYRIDIN-8-AMINE Chemical Properties,Usage,Production
Synthesis
38875-53-5
2032-35-1
676371-00-9
General procedure for the synthesis of 6-bromoimidazo[1,2-A]pyridin-8-amine from 2,3-diamino-5-bromopyridine and bromoacetaldehyde diethyl acetal: Concentrated hydrochloric acid (0.3 mL) was added to a solution of bromoacetaldehyde diethyl acetal (2.37 mL, 15.4 mmol) in dioxane/water (2:1, 15 mL) at room temperature and the mixture was refluxed for 30 min. After cooling the mixture to room temperature, sodium bicarbonate (2.6 g, 30.8 mmol) was carefully added, followed by dropwise addition of 2,3-diamino-5-bromopyridine (1.5 g, 7.7 mmol) in dioxane/water (2:1, 15 mL). The resulting mixture was stirred under reflux conditions for 14 hours and then cooled to room temperature. The mixture was diluted with 1 M sodium hydroxide solution (30 mL) and extracted with dichloromethane (3 x 35 mL). The organic layers were combined, washed with brine (20 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 1.5 g (92% yield) of the target product, 6-bromoimidazo[1,2-A]pyridin-8-amine, with mass spectrometry analysis revealing [M+H]+=214.0.
References
[1] Patent: WO2004/26867, 2004, A2. Location in patent: Page 32-33
6-BROMO-IMIDAZO[1,2-A]PYRIDIN-8-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-BROMO-IMIDAZO[1,2-A]PYRIDIN-8-AMINE manufacturers
- Product
- 6-BROMO-IMIDAZO[1,2-A]PYRIDIN-8-AMINE 676371-00-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2019-12-30