METHYL 3-METHOXY-4-METHYLBENZOATE
Preparation- Product Name
- METHYL 3-METHOXY-4-METHYLBENZOATE
- CAS No.
- 3556-83-0
- Chemical Name
- METHYL 3-METHOXY-4-METHYLBENZOATE
- Synonyms
- METHYL 4-METHYL-M-ANISATE;METHYL 3-METHOXY-P-TOLUATE;METHYL 3-METHOXY-4-METHYLBENZOATE;4-METHYL-M-ANISIC ACID METHYL ESTER;Methyl3-Methoxy-4-methylbenzoate>3-METHOXY-P-TOLUIC ACID METHYL ESTER;Methyl 4-methyl-3-(methyloxy)benzoate;Methyl 3-methoxy-4-methylbenzoate, 98+%;3-Methoxy-4-methylbenzoate methyl ester;3-Methoxy-4-methyl-benzoesuremethylester
- CBNumber
- CB9372636
- Molecular Formula
- C10H12O3
- Formula Weight
- 180.2
- MOL File
- 3556-83-0.mol
METHYL 3-METHOXY-4-METHYLBENZOATE Property
- Melting point:
- 50-54 °C (lit.)
- Boiling point:
- 119-120°C 1mm
- Density
- 1.075±0.06 g/cm3(Predicted)
- refractive index
- 1.5295
- Flash point:
- >230 °F
- form
- powder to crystal
- color
- White to Almost white
- BRN
- 1948339
- CAS DataBase Reference
- 3556-83-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 528781
- Product name
- Methyl 3-methoxy-4-methylbenzoate
- Purity
- 96%
- Packaging
- 25g
- Price
- $885
- Updated
- 2023/06/20
- Product number
- M1427
- Product name
- Methyl 3-Methoxy-4-methylbenzoate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $40
- Updated
- 2024/03/01
- Product number
- M1427
- Product name
- Methyl 3-Methoxy-4-methylbenzoate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $132
- Updated
- 2024/03/01
- Product number
- B22695
- Product name
- Methyl 3-methoxy-4-methylbenzoate, 98%
- Packaging
- 5g
- Price
- $100.65
- Updated
- 2024/03/01
- Product number
- B22695
- Product name
- Methyl 3-methoxy-4-methylbenzoate, 98%
- Packaging
- 1g
- Price
- $39.5
- Updated
- 2021/12/16
METHYL 3-METHOXY-4-METHYLBENZOATE Chemical Properties,Usage,Production
Preparation
Methyl 3-methoxy-4-methylbenzoate is synthesized by the following steps:A mixture of methyl 3-hydroxy-4-methylbenzoate 36 (25 g, 0.151 mol), Me2SO4 (28.3 ml, 0.386 mol), anhydrous K2CO3 (103.5 g, 0.75 mol) was refluxed in acetone for 2 hours. K2CO3 was filtered off, washed thoroughly with acetone. The filtrates were combined and concentrated, the residue was redissolved in EtOAc washed with water, dried (anhydrous Na2SO4), filtered and concentrated in vacuo to furnish a white solid (19.52 g). Yield : 72%.
Chemical Properties
White low melting solid
Uses
Methyl 3-Methoxy-4-methylbenzoate has been used as a reactant in the preparation of an antimalaria drug that consists of the 4-aminoquinoline pharmacophore of chloroquine with clotrimazole-based antimalarials.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 33, p. 1771, 1990 DOI: 10.1021/jm00168a036
General Description
Methyl 3-methoxy-4-methylbenzoate can be prepared by reacting diazomethane with 3-methoxy-4-methylbenzoic acid in ether.
METHYL 3-METHOXY-4-METHYLBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 3-METHOXY-4-METHYLBENZOATE Suppliers
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- Country
- France
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View Lastest Price from METHYL 3-METHOXY-4-METHYLBENZOATE manufacturers
- Product
- Methyl 3-methoxy-4-methylbenzoate 3556-83-0
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 200kgs
- Release date
- 2020-01-09