GANODERIC ACID A
- Product Name
- GANODERIC ACID A
- CAS No.
- 81907-62-2
- Chemical Name
- GANODERIC ACID A
- Synonyms
- (2R,6R);Aids070759;Aids-070759;GANODERIC ACID A;GANODERIC ACID A(P);Ganoderic acid A-RM;Ganoderic acid A, >98%;-6-((7S,10S,13R,14R,15S,17R);-2-methyl-4-oxoheptanoic acid;Ganoderic acid A, 10 mM in DMSO
- CBNumber
- CB9373916
- Molecular Formula
- C30H44O7
- Formula Weight
- 516.67
- MOL File
- 81907-62-2.mol
GANODERIC ACID A Property
- Melting point:
- 118～123℃
- Boiling point:
- 690.1±55.0 °C(Predicted)
- Density
- 1.22
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly, Sonicated), Methanol (Slightly)
- form
- Solid
- pka
- 4.78±0.23(Predicted)
- color
- White to Pale Yellow
- InChIKey
- OVUOUFPIPZJGME-YYJACZGBNA-N
- SMILES
- [C@@]12(C)[C@@H](O)C[C@H](/C(/C)=C/C(=O)CC(C)C(O)=O)[C@@]1(C)CC(=O)C1[C@@]3([C@]([H])(C(C)(C)C(CC3)=O)C[C@H](O)C2=1)C |&1:0,2,5,17,23,24,34,r|
Safety
- Safety Statements
- 24/25
- HS Code
- 29189900
N-Bromosuccinimide Price
- Product number
- Y0002190
- Product name
- Ganoderic acid A
- Purity
- CRS European Pharmacopoeia (EP) Reference Standard
- Packaging
- 20 mg
- Price
- $167
- Updated
- 2025/07/31
- Product number
- SMB00445
- Product name
- Ganoderic acid A
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $407
- Updated
- 2025/07/31
- Product number
- PHL89668
- Product name
- Ganoderic acid A
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $601
- Updated
- 2025/07/31
- Product number
- 1288383
- Product name
- Ganoderic acid A
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 50MG
- Price
- $654
- Updated
- 2025/07/31
- Product number
- Y0002190
- Product name
- Ganoderic acid A
- Purity
- CRS European Pharmacopoeia (EP) Reference Standard
- Packaging
- Y0002190
- Price
- $156
- Updated
- 2024/03/01
GANODERIC ACID A Chemical Properties,Usage,Production
Description
Ganoderic acid A is a triterpene that has been found in Ganoderma and has diverse biological activities. It reduces cell viability, expression of superoxide dismutase 1 (SOD1), SOD2, and SOD3, and production of reactive oxygen species (ROS) in PC3 prostate cancer cells. Ganoderic acid A (2-100 μg/ml) reduces hypoxia-induced apoptosis in H9c2 cardiomyocytes. It inhibits LPS-induced activation of NF-κB, release of TNF-α, IL-1β, and IL-6, and mitochondrial activity in primary mouse cortical microglia. Ganoderic acid A (20 and 40 mg/kg) reduces lung myeloperoxidase (MPO) activity, neutrophil infiltration, and NF-κB signaling, as well as bronchoalveolar lavage fluid (BALF) levels of TNF-α, IL-1β, and IL-6 in a mouse model of LPS-induced lung injury. It also reduces weight gain and hepatic lipid accumulation and improves insulin sensitivity in a mouse model of high-fat diet-induced obesity.
Chemical Properties
White powder
Uses
Ganoderic Acid A, is a new lanostanoid triterpene extracted from the fruit bodies of Ganoderma Lucidum mushroom. these compounds are shown to possess many therapeutic properties. They can be used as anti-virus, anti-inflammation, anti-tumor, immunity-promoting, anti-diabetic, etc.
Definition
ChEBI: Ganoderic acid A is a triterpenoid.
in vivo
Ganoderic acid A treatment significantly prolonged survival of EL4 challenged mice and decreased tumor metastasis to the liver[4].
References
[1] B. S. GILL N Sanjeev Kumar. Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer[J]. Molecular Biology Reports, 2016, 43 1: 1411-1422. DOI: 10.1007/s11033-016-4074-z
[2] BAOJIN CHI. Effects of ganoderic acid A on lipopolysaccharide-induced proinflammatory cytokine release from primary mouse microglia cultures.[J]. Experimental and therapeutic medicine, 2018, 15 1: 847-853. DOI: 10.3892/etm.2017.5472
[3] BING WAN. Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice.[J]. Bioscience Reports, 2019. DOI: 10.1042/bsr20190301
[4] JING ZHU . Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway[J]. Chemico-Biological Interactions, 2018, 290: Pages 77-87. DOI: 10.1016/j.cbi.2018.05.014
GANODERIC ACID A Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from GANODERIC ACID A manufacturers
- Product
- Ganoderic Acid A 81907-62-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000ton
- Release date
- 2023-08-21
- Product
- Ganoderic Acid A 81907-62-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-12-26
- Product
- GANODERIC ACID A 81907-62-2
- Price
- US $8.00/KG
- Min. Order
- 1g
- Purity
- ＞98% HPLC
- Supply Ability
- kg--ton
- Release date
- 2020-02-20