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GANODERIC ACID A

Product Name
GANODERIC ACID A
CAS No.
81907-62-2
Chemical Name
GANODERIC ACID A
Synonyms
(2R,6R);Aids070759;Aids-070759;GANODERIC ACID A;GANODERIC ACID A(P);Ganoderic acid A-RM;Ganoderic acid A, >98%;-6-((7S,10S,13R,14R,15S,17R);-2-methyl-4-oxoheptanoic acid;Ganoderic acid A, 10 mM in DMSO
CBNumber
CB9373916
Molecular Formula
C30H44O7
Formula Weight
516.67
MOL File
81907-62-2.mol
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GANODERIC ACID A Property

Melting point:
118～123℃
Boiling point:
690.1±55.0 °C(Predicted)
Density 
1.22
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Chloroform (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
pka
4.78±0.23(Predicted)
color 
White to Pale Yellow
InChIKey
OVUOUFPIPZJGME-YYJACZGBNA-N
SMILES
[C@@]12(C)[C@@H](O)C[C@H](/C(/C)=C/C(=O)CC(C)C(O)=O)[C@@]1(C)CC(=O)C1[C@@]3([C@]([H])(C(C)(C)C(CC3)=O)C[C@H](O)C2=1)C |&1:0,2,5,17,23,24,34,r|
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Safety

Safety Statements 
24/25
HS Code 
29189900
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0002190
Product name
Ganoderic acid A
Purity
CRS European Pharmacopoeia (EP) Reference Standard
Packaging
20 mg
Price
$167
Updated
2025/07/31
Sigma-Aldrich
Product number
SMB00445
Product name
Ganoderic acid A
Purity
≥98% (HPLC)
Packaging
5MG
Price
$407
Updated
2025/07/31
Sigma-Aldrich
Product number
PHL89668
Product name
Ganoderic acid A
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$601
Updated
2025/07/31
Sigma-Aldrich
Product number
1288383
Product name
Ganoderic acid A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50MG
Price
$654
Updated
2025/07/31
Sigma-Aldrich
Product number
Y0002190
Product name
Ganoderic acid A
Purity
CRS European Pharmacopoeia (EP) Reference Standard
Packaging
Y0002190
Price
$156
Updated
2024/03/01
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GANODERIC ACID A Chemical Properties,Usage,Production

Description

Ganoderic acid A is a triterpene that has been found in Ganoderma and has diverse biological activities. It reduces cell viability, expression of superoxide dismutase 1 (SOD1), SOD2, and SOD3, and production of reactive oxygen species (ROS) in PC3 prostate cancer cells. Ganoderic acid A (2-100 μg/ml) reduces hypoxia-induced apoptosis in H9c2 cardiomyocytes. It inhibits LPS-induced activation of NF-κB, release of TNF-α, IL-1β, and IL-6, and mitochondrial activity in primary mouse cortical microglia. Ganoderic acid A (20 and 40 mg/kg) reduces lung myeloperoxidase (MPO) activity, neutrophil infiltration, and NF-κB signaling, as well as bronchoalveolar lavage fluid (BALF) levels of TNF-α, IL-1β, and IL-6 in a mouse model of LPS-induced lung injury. It also reduces weight gain and hepatic lipid accumulation and improves insulin sensitivity in a mouse model of high-fat diet-induced obesity.

Chemical Properties

White powder

Uses

Ganoderic Acid A, is a new lanostanoid triterpene extracted from the fruit bodies of Ganoderma Lucidum mushroom. these compounds are shown to possess many therapeutic properties. They can be used as anti-virus, anti-inflammation, anti-tumor, immunity-promoting, anti-diabetic, etc.

Definition

ChEBI: Ganoderic acid A is a triterpenoid.

in vivo

Ganoderic acid A treatment significantly prolonged survival of EL4 challenged mice and decreased tumor metastasis to the liver[4].

References

[1] B. S. GILL N Sanjeev Kumar. Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer[J]. Molecular Biology Reports, 2016, 43 1: 1411-1422. DOI: 10.1007/s11033-016-4074-z
[2] BAOJIN CHI. Effects of ganoderic acid A on lipopolysaccharide-induced proinflammatory cytokine release from primary mouse microglia cultures.[J]. Experimental and therapeutic medicine, 2018, 15 1: 847-853. DOI: 10.3892/etm.2017.5472
[3] BING WAN. Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice.[J]. Bioscience Reports, 2019. DOI: 10.1042/bsr20190301
[4] JING ZHU . Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway[J]. Chemico-Biological Interactions, 2018, 290: Pages 77-87. DOI: 10.1016/j.cbi.2018.05.014

GANODERIC ACID A Preparation Products And Raw materials

Raw materials

Preparation Products

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GANODERIC ACID A Suppliers

China 222 India 1 United Kingdom 4 United States 23 Global 250
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View Lastest Price from GANODERIC ACID A manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Ganoderic Acid A 81907-62-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000ton
Release date
2023-08-21
Shanghai Standard Technology Co., Ltd.
Product
Ganoderic Acid A 81907-62-2
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-12-26
Career Henan Chemical Co
Product
GANODERIC ACID A 81907-62-2
Price
US $8.00/KG
Min. Order
1g
Purity
＞98% HPLC
Supply Ability
kg--ton
Release date
2020-02-20

81907-62-2, GANODERIC ACID ARelated Search:

GANODERIC ACID A BETA-CYCLOCITRAL Ganoderic acid C GANODERIC ACID C1 Ganoderic acid B ganodermic acid S Ganoderic acidα Ganoderic acid I Ganoderic acid T-Q GANODERIC ACID H GANODERIC ACID F(SH),Ganoderic acid E Ganoderic acid X Ganoderic acid T GANODERIC ACID DM GANODERIC ACID C2(SH) Ganoderic acid F Ganoderic acid W Ganoderic acid Y

  • (25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oic acid
  • Aids070759
  • Aids-070759
  • Lanost-8-en-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7.beta.,15.alpha.,25R)-
  • (7beta,15alpha,25R)-7,15-Dihydroxy-3,11,23-trioxo-lanost-8-en-26-oic acid
  • GANODERIC ACID A(P)
  • GANODERIC ACID A
  • (25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oicaci
  • Ganoderic acid A, froM GanoderMa luciduM
  • (2R,6R)-6-((7S,10S,13R,14R,15S,17R)-7,15-Dihydroxy-4,4,10,13,14-pentaMethyl-3,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-Methyl-4-oxoheptanoic acid
  • (2R,6R)
  • -2-methyl-4-oxoheptanoic acid
  • -6-((7S,10S,13R,14R,15S,17R)
  • Ganoderic acid A, >98%
  • -7,15-Dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)
  • (2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
  • Ganoderic acid A, 98%, from Micromeria biflora (Buch.-Ham. ex D. Don) Benth.
  • Lanost-8-en-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7β,15α,25R)-
  • (2R,6R)-6-((5R,7S,10S,13R,14R,15S,17R)-7,15-Dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid
  • GANODERIC ACID A METHYLESTER(AS) 10mg
  • GANODERIC ACID A METHYLESTER(AS) 5mg
  • Ganoderic acid A-RM
  • Pirlindole Impurity 2 Hydrobromide
  • Ganoderic acid A, 10 mM in DMSO
  • 81907-62-2
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract