ChemicalBook > CAS DataBase List > GANODERIC ACID A

GANODERIC ACID A

Product Name: GANODERIC ACID A
CAS No.: 81907-62-2
Chemical Name: GANODERIC ACID A
Synonyms: (2R,6R);Aids070759;Aids-070759;GANODERIC ACID A;GANODERIC ACID A(P);Ganoderic acid A-RM;Ganoderic acid A, >98%;-6-((7S,10S,13R,14R,15S,17R);-2-methyl-4-oxoheptanoic acid;Ganoderic acid A, 10 mM in DMSO
CBNumber: CB9373916
Molecular Formula: C30H44O7
Formula Weight: 516.67
MOL File: 81907-62-2.mol

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GANODERIC ACID A Property

Melting point:: 118～123℃
Boiling point:: 690.1±55.0 °C(Predicted)
Density: 1.22
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Chloroform (Slightly, Sonicated), Methanol (Slightly)
form: Solid
pka: 4.78±0.23(Predicted)
color: White to Pale Yellow
InChIKey: OVUOUFPIPZJGME-YYJACZGBNA-N
SMILES: [C@@]12(C)[C@@H](O)C[C@H](/C(/C)=C/C(=O)CC(C)C(O)=O)[C@@]1(C)CC(=O)C1[C@@]3([C@]([H])(C(C)(C)C(CC3)=O)C[C@H](O)C2=1)C |&1:0,2,5,17,23,24,34,r|

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Safety

Safety Statements: 24/25
HS Code: 29189900

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0002190
Product name: Ganoderic acid A
Purity: CRS European Pharmacopoeia (EP) Reference Standard
Packaging: 20 mg
Price: $167
Updated: 2025/07/31

Sigma-Aldrich

Product number: SMB00445
Product name: Ganoderic acid A
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $407
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHL89668
Product name: Ganoderic acid A
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $601
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1288383
Product name: Ganoderic acid A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 50MG
Price: $654
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0002190
Product name: Ganoderic acid A
Purity: CRS European Pharmacopoeia (EP) Reference Standard
Packaging: Y0002190
Price: $156
Updated: 2024/03/01

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GANODERIC ACID A Chemical Properties,Usage,Production

Description

Ganoderic acid A is a triterpene that has been found in Ganoderma and has diverse biological activities. It reduces cell viability, expression of superoxide dismutase 1 (SOD1), SOD2, and SOD3, and production of reactive oxygen species (ROS) in PC3 prostate cancer cells. Ganoderic acid A (2-100 μg/ml) reduces hypoxia-induced apoptosis in H9c2 cardiomyocytes. It inhibits LPS-induced activation of NF-κB, release of TNF-α, IL-1β, and IL-6, and mitochondrial activity in primary mouse cortical microglia. Ganoderic acid A (20 and 40 mg/kg) reduces lung myeloperoxidase (MPO) activity, neutrophil infiltration, and NF-κB signaling, as well as bronchoalveolar lavage fluid (BALF) levels of TNF-α, IL-1β, and IL-6 in a mouse model of LPS-induced lung injury. It also reduces weight gain and hepatic lipid accumulation and improves insulin sensitivity in a mouse model of high-fat diet-induced obesity.

Chemical Properties

White powder

Uses

Ganoderic Acid A, is a new lanostanoid triterpene extracted from the fruit bodies of Ganoderma Lucidum mushroom. these compounds are shown to possess many therapeutic properties. They can be used as anti-virus, anti-inflammation, anti-tumor, immunity-promoting, anti-diabetic, etc.

Definition

ChEBI: Ganoderic acid A is a triterpenoid.

in vivo

Ganoderic acid A treatment significantly prolonged survival of EL4 challenged mice and decreased tumor metastasis to the liver^[4].

References

[1] B. S. GILL N Sanjeev Kumar. Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer[J]. Molecular Biology Reports, 2016, 43 1: 1411-1422. DOI: 10.1007/s11033-016-4074-z
[2] BAOJIN CHI. Effects of ganoderic acid A on lipopolysaccharide-induced proinflammatory cytokine release from primary mouse microglia cultures.[J]. Experimental and therapeutic medicine, 2018, 15 1: 847-853. DOI: 10.3892/etm.2017.5472
[3] BING WAN. Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice.[J]. Bioscience Reports, 2019. DOI: 10.1042/bsr20190301
[4] JING ZHU . Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway[J]. Chemico-Biological Interactions, 2018, 290: Pages 77-87. DOI: 10.1016/j.cbi.2018.05.014

GANODERIC ACID A Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from GANODERIC ACID A manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Ganoderic Acid A 81907-62-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000ton
Release date: 2023-08-21

Shanghai Standard Technology Co., Ltd.

Product: Ganoderic Acid A 81907-62-2
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-26

Career Henan Chemical Co

Product: GANODERIC ACID A 81907-62-2
Price: US $8.00/KG
Min. Order: 1g
Purity: ＞98% HPLC
Supply Ability: kg--ton
Release date: 2020-02-20

81907-62-2, GANODERIC ACID ARelated Search:

GANODERIC ACID A BETA-CYCLOCITRAL Ganoderic acid C GANODERIC ACID C1 Ganoderic acid B ganodermic acid S Ganoderic acidα Ganoderic acid I Ganoderic acid T-Q GANODERIC ACID H GANODERIC ACID F(SH),Ganoderic acid E Ganoderic acid X Ganoderic acid T GANODERIC ACID DM GANODERIC ACID C2(SH) Ganoderic acid F Ganoderic acid W Ganoderic acid Y

(25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oic acid

Aids070759

Aids-070759

Lanost-8-en-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7.beta.,15.alpha.,25R)-

(7beta,15alpha,25R)-7,15-Dihydroxy-3,11,23-trioxo-lanost-8-en-26-oic acid

GANODERIC ACID A(P)

GANODERIC ACID A

(25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oicaci

Ganoderic acid A, froM GanoderMa luciduM

(2R,6R)-6-((7S,10S,13R,14R,15S,17R)-7,15-Dihydroxy-4,4,10,13,14-pentaMethyl-3,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-Methyl-4-oxoheptanoic acid

(2R,6R)

-2-methyl-4-oxoheptanoic acid

-6-((7S,10S,13R,14R,15S,17R)

Ganoderic acid A, >98%

-7,15-Dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)

(2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid

Ganoderic acid A, 98%, from Micromeria biflora (Buch.-Ham. ex D. Don) Benth.

Lanost-8-en-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7β,15α,25R)-

(2R,6R)-6-((5R,7S,10S,13R,14R,15S,17R)-7,15-Dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid

GANODERIC ACID A METHYLESTER(AS) 10mg

GANODERIC ACID A METHYLESTER(AS) 5mg

Ganoderic acid A-RM

Pirlindole Impurity 2 Hydrobromide

Ganoderic acid A, 10 mM in DMSO

81907-62-2

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract