A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE

Product Name: A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE
CAS No.: 165806-95-1
Chemical Name: A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE
Synonyms: MethanidylidyneazaniuM;A-TOSYL-(4-FLUOROBENZYL) ISOCYANIDE;Alpha-tosyl-(4-fluorobenzal)isocyanide;Alpha-Tosyl-(4-fluorobenzyl) isocyanide;a-(p-Toluenesulfonyl)-4-fluorobenzylison;1-fluoro-4-(isocyano(tosyl)methyl)benzene;[1-(4-FLUOROPHENYL)-1-TOSYL]METHYL ISOCYANIDE;a-(p-Toluenesulfonyl)-4-fluorobezylisonitrile;α-(p-Toluenesulfonyl)-4-fluorobenzylisonitrile;A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE
CBNumber: CB9382376
Molecular Formula: C15H12FNO2S
Formula Weight: 289.32
MOL File: 165806-95-1.mol

More

Less

A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE Property

Melting point:: >89°C (dec.)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: Off-White to Light Orange
InChI: InChI=1S/C15H12FNO2S/c1-11-3-9-14(10-4-11)20(18,19)15(17-2)12-5-7-13(16)8-6-12/h3-10,15H,1H3
InChIKey: UXCQPEDHCCJBNL-UHFFFAOYSA-N
SMILES: C(C1C=CC(F)=CC=1)([N+]#[C-])S(C1C=CC(C)=CC=1)(=O)=O

More

Less

Safety

Hazard Codes: Xi
HS Code: 2930909899

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TRC

Product number: P768818
Product name: α-(p-Toluenesulfonyl)-4-fluorobenzylisonitrile
Packaging: 100mg
Price: $75
Updated: 2021/12/16

TRC

Product number: P768818
Product name: α-(p-Toluenesulfonyl)-4-fluorobenzylisonitrile
Packaging: 1g
Price: $500
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8763-3-X0
Product name: alpha-[(4-Methylphenyl)sulfonyl]-4-fluorobenzylisonitrile
Packaging: 5G
Price: $402
Updated: 2021/12/16

Apolloscientific

Product number: PC8908
Product name: (4-Fluorophenyl)(isocyano)methyl4-methylphenylsulphone
Purity: 98%
Packaging: 10g
Price: $474
Updated: 2021/12/16

Matrix Scientific

Product number: 071803
Product name: Alpha-Tosyl-(4-fluorobenzyl) isocyanide
Purity: 95+%
Packaging: 5g
Price: $700
Updated: 2021/12/16

More

Less

A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE Chemical Properties,Usage,Production

Uses

Alpha-(p-toluenesulfonyl)-4-fluorobenzylisonitrile is a useful reagent for the development of DNA-compatible method for novel functionalized imidazoles.

Synthesis

165806-94-0

165806-95-1

4-Fluorophenyl-toluenesulfonylmethylformamide (2.01 g, 6.25 mmol) was used as the raw material, which was dissolved in DME (32 mL) and cooled to -10 °C. POCl3 (1.52 mL, 16.3 mmol) and triethylamine (4.6 mL, 32.6 mmol, dissolved in DME 3 mL) were added sequentially while keeping the internal temperature below -5 °C. The reaction mixture was slowly warmed to room temperature over 1 h and subsequently poured into water and extracted with EtOAc. The organic phase was washed with saturated aqueous NaHCO3, dried over Na2SO4 and concentrated. The residue was ground with petroleum ether and filtered to give α-tosyl(4-fluorobenzyl)isonitrile (1.7 g, 90% yield).1H NMR (CDCl3) δ 7.63 (d, 2H), 7.33 (m, 4H), 7.10 (t, 2H), 5.60 (s, 1H), 2.50 (s, 3H).

References

[1] Patent: US6046208, 2000, A
[2] Patent: US5658903, 1997, A
[3] Patent: US5716955, 1998, A
[4] Patent: US5739143, 1998, A
[5] Patent: US5756499, 1998, A

A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE Suppliers

China 75 China Hong Kong 1 Germany 2 India 4 United Kingdom 5 United States 14 Global 101

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

NovoChemy Ltd.

Tel: 021-31261262/ 49 (0)17662837245
Fax: (0)21-33250524
Email: sales@novochemy.com
Country: Germany
ProdList: 6328
Advantage: 58

Runpharm Technology Limited

Tel: 18171398856 2968382473
Fax: 0086-21-50758330
Email: service@runpharm.com
Country: China
ProdList: 716
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Shanghai Run-Biotech Co., Ltd.

Tel: 021-57171705 13817537615
Fax: QQ3095748324
Email: sales@run-biotech.com
Country: China
ProdList: 2339
Advantage: 58

Xunteng International Trading Co.,Limited

Tel
Country: China Hong Kong
ProdList: 878
Advantage: 55

More

Less

View Lastest Price from A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE 165806-95-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 97%
Supply Ability: 2000
Release date: 2025-09-25

Shaanxi Dideu New Materials Co. Ltd

Product: A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE 165806-95-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-07-04

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: A-TOSYL-(4-FLUOROBENZYL) ISOCYANIDE 165806-95-1
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-27

165806-95-1, A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILERelated Search:

A-TOSYL-(4-CHLOROBENZYL) ISOCYANIDE [1-(3-FLUOROPHENYL)-1-TOSYL]METHYL ISOCYANIDE [1-(2-FLUOROPHENYL)-1-TOSYL]METHYL ISOCYANIDE (1-PHENYL-1-TOSYL)METHYL ISOCYANIDE α-Tosyl-(2,4-difluorobenzyl)isocyanide A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE METHYL ISOCYANIDE PHENYLSULFONYLMETHYL ISOCYANIDE 4-FLUOROBENZYLISOCYANIDE 4-FLUOROBENZYL PHENYL SULFIDE 1-METHYL-1-TOSYLMETHYL ISOCYANIDE 2-CHLORO-4-FLUORO-1-[ISOCYANO-(TOLUENE-4-SULFONYL)-METHYL]-BENZENE

A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE

A-TOSYL-(4-FLUOROBENZYL) ISOCYANIDE

ALPHA-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE

ALPHA-(P-TOLUENESULFONYL)-4-FLUOROBEZYLISONITRILE

[1-(4-FLUOROPHENYL)-1-TOSYL]METHYL ISOCYANIDE

α-(p-Toluenesulfonyl)-4-fluorobenzylisonitrile

(4-Fluorophenyl)(isocyano)methyl 4-methylphenyl sulphone

Benzene,1-fluoro-4-[isocyano[(4-Methylphenyl)sulfonyl]Methyl]-

Alpha-tosyl-(4-fluorobenzal)isocyanide

alpha-[(4-Methylphenyl)sulphonyl]-4-fluoroBenzylisonitrile

1-{[(4-fluorophenyl)Methane]sulfonyl}-4-Methylbenzene

MethanidylidyneazaniuM

Alpha-Tosyl-(4-fluorobenzyl) isocyanide

4-Fluoro-alpha-(toluene-4-sulphonyl)benzyl isocyanide, (4-Fluorophenyl)(isocyano)methyl p-tolyl sulphone

a-(p-Toluenesulfonyl)-4-fluorobezylisonitrile

1-fluoro-4-(isocyano(tosyl)methyl)benzene

1-[(4-fluorophenyl)(isocyano)Methanesulfonyl]-4- Methylbenzene

α-(p-toluenesulfonyl)-4-fluorobenzylisocyanide

alpha-[(4-Methylphenyl)sulfonyl]-4-fluorobenzylisonitrile

a-(p-Toluenesulfonyl)-4-fluorobenzylison

^a-(p-Toluenesulfonyl)-4-fluorobenzylisonitrile,97%

A-(P-TOLUENESULFONYL)-4-FLUOROBENZYLISONITRILE ISO 9001：2015 REACH

1-fluoro-4-[isocyano(4-methylbenzenesulfonyl)methyl]benzene

1-[(4-fluorophenyl)-isocyanomethyl]sulfonyl-4-methylbenzene

A-(P-Toluenesulfonyl)-4-fluorobenzylisocyanide

165806-95-1

C15H12FNO2S