5-Chloro-6-hydroxynicotinic Acid

Structure

Product Name: 5-Chloro-6-hydroxynicotinic Acid
CAS No.: 54127-63-8
Chemical Name: 5-Chloro-6-hydroxynicotinic Acid
Synonyms: TIMTEC-BB SBB003814;Avatrombopag Impurity 53;Nicotinic Acid Impurity 16;oro-6-hydroxynicotinic Acid;5-CHLORO-6-HYDROXYNICOTINIC ACID;5-Chloro-6-hydroxynicotinicacid,98%;5-Chloro-6-hydroxynicotinic acid 98%;5-Chloro-6-hydroxynicotinic Acid >5-CHLORO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;3-CHLORO-2-HYDROXYPYRIDINE-5-CARBOXYLIC ACID
CBNumber: CB9399994
Molecular Formula: C6H4ClNO3
Formula Weight: 173.55
MOL File: 54127-63-8.mol

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5-Chloro-6-hydroxynicotinic Acid Property

Melting point:: ≥300 °C(lit.)
Boiling point:: 334.6±42.0 °C(Predicted)
Density: 1.4914 (rough estimate)
refractive index: 1.5810 (estimate)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
pka: 3.38±0.50(Predicted)
color: White to Light yellow to Light orange
CAS DataBase Reference: 54127-63-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-37/39-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C1758
Product name: 5-Chloro-6-hydroxynicotinic Acid
Purity: >95.0%(GC)(T)
Packaging: 5g
Price: $19
Updated: 2024/03/01

Alfa Aesar

Product number: A15737
Product name: 5-Chloro-6-hydroxynicotinic acid, 98%
Packaging: 5g
Price: $40.65
Updated: 2024/03/01

Alfa Aesar

Product number: A15737
Product name: 5-Chloro-6-hydroxynicotinic acid, 98%
Packaging: 25g
Price: $152.65
Updated: 2024/03/01

TRC

Product number: C422058
Product name: 5-Chloro-6-hydroxynicotinic Acid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C422058
Product name: 5-Chloro-6-hydroxynicotinic Acid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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5-Chloro-6-hydroxynicotinic Acid Chemical Properties,Usage,Production

Structure

5-Chloro-6-hydroxynicotinic Acid （5Cl6HNA) was recrystallized four times from ethanol at 345 K. The obtained white crystalline solid was first dried in a vacuum at 1.3 Pa and 353 K. The crystals were then ground with a mortar and a pestle and further dried for 24 h at 1.3 Pa and 353 K. The powder pattern obtained at 295 ± 1 K was indexed as monoclinic, space group P21/c, with a= 5.478 Å, b= 10.545 Å, c= 11.796 Å, β=97.76°. These results are in agreement with those obtained in this work from single crystal X-ray diffraction experiments carried out at 293 ±2K(P21/c, a ) 5.469 Å, b = 10.529 Å, c= 11.795 Å, β= 97.72°). DSC (fusion, β= 2 K ·min-1 ): Ton= 582.2 K and Tmax= 585.6 K[1].

Chemical Properties

white to beige fine crystalline powder

References

[1] Rui C. Santos. “Energetics and Structure of Hydroxynicotinic Acids. Crystal Structures of 2-, 4-, 6-Hydroxynicotinic and 5-Chloro-6-hydroxynicotinic Acids.” The Journal of Physical Chemistry B 113 43 (2009): 14291–14309.

5-Chloro-6-hydroxynicotinic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-Chloro-6-hydroxynicotinic Acid manufacturers

R&D Scientific Inc.

Product: 5-chloro-6-hydroxynicotinic acid 54127-63-8
Price: US $780.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-02-19

Hebei Zhanyao Biotechnology Co. Ltd

Product: 5-Chloro-6-hydroxy-3-pyridinecarboxylic acid 54127-63-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 TONS
Release date: 2021-10-15

Dideu Industries Group Limited

Product: 5-Chloro-6-hydroxy-3-pyridinecarboxylic acid 54127-63-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-22

54127-63-8, 5-Chloro-6-hydroxynicotinic AcidRelated Search:

2-Hydroxy-5-pyridinecarboxylic acid Nicotinic acid Ethyl 2-aminopyridine-3-carboxylate 3-Nitropyridine NICOTINIC-D4 ACID Isonicotinic acid 2-Aminopyridine N-oxide 3,5-DINITROPYRIDINE 2-BROMOPYRIDINE N-OXIDE 2,5-PYRIDINEDICARBOXYLIC ACID 3-Ethylpyridine 5-Ethyl-2-methylpyridine 2,2'-Bipyridine-5,5'-dicarboxylic acid 5-NITRONICOTINIC ACID 5-chloro-6-hydroxynicotinonitrile 5-Chloro-4,6-dihydroxynicotinic acid ethyl ester 5-Choro-6-methoxynicotinic acid 5-chloro-2-hydroxy-3-pyridinecarboxylic acid

3-CHLORO-2-HYDROXYPYRIDINE-5-CARBOXYLIC ACID

TIMTEC-BB SBB003814

5-CHLORO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID

5-CHLORO-6-HYDROXYNICOTINIC ACID

5-CHLORO-6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID

5-Chloro-6-hydroxynicotinicacid,98%

3-Chloro-2-hydroxypyridine-5-carboxylic acid 98%

3-Chloro-2-hydroxypyridine-5-carboxylicacid98%

5-Chloro-6-hydroxynicotinic acid,98%,mixtureof tautomers

5-Chloro-6-hydroxynicotinic acid 98%

5-Chloro-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid

5-Chloro-6-hydroxynicotinic Acid &gt

oro-6-hydroxynicotinic Acid

3-Pyridinecarboxylic acid, 5-chloro-1,6-dihydro-6-oxo-

Nicotinic Acid Impurity 16

5-Chloro-6-hydroxy-3-pyridinecarboxylic acid ISO 9001：2015 REACH

5-chloro-6-oxo-1H-pyridine-3-carboxylic acid

Avatrombopag Impurity 53

54127-63-8

C6H7NClO3

Building Blocks

Pyridines

Heterocyclic Building Blocks

Halogenated Heterocycles

Halopyridines

Chloropyridines

Building Blocks

C5 to C6

C6 to C7

Chemical Synthesis

Halogenated Heterocycles

Heterocyclic Building Blocks

Chloropyridines

Halopyridines

Carboxylic Acids

Boronic Acid

Pyridine

Carboxylic Acids

Pyridines

Organic acids