ChemicalBook > CAS DataBase List > Trimeprazine tartrate

Trimeprazine tartrate

Product Name: Trimeprazine tartrate
CAS No.: 4330-99-8
Chemical Name: Trimeprazine tartrate
Synonyms: temaril;repeltin;panectyl;vanectyl;vallergan;theralene;NSC 17475;Temaril 16;Alimernazine;N,N,β-TriMethyl-
CBNumber: CB9407912
Molecular Formula: C22H28N2O6S
Formula Weight: 448.53
MOL File: 4330-99-8.mol

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Trimeprazine tartrate Property

Melting point:: 153-155°C
storage temp.: Inert atmosphere,Room Temperature
solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml; PBS (pH 7.2): insol
form: Solid
color: White to Almost white
Merck: 14,9704
InChIKey: ZEEPCWVFSHMOPI-MVELKYERNA-N
SMILES: C(N1C2=CC=CC=C2SC2C=CC=CC1=2)C(C)CN(C)C.[C@H](O)(C(=O)O)[C@@H](O)C(=O)O |&1:21,26,r|
CAS DataBase Reference: 4330-99-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36
RIDADR: 3249
WGK Germany: 3
RTECS: SO6475000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 2934302700

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001583
Product name: Alimemazine hemitartrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 15 mg
Price: $118
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0001581
Product name: Alimemazine for system suitability
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 5 mg
Price: $153
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR1749
Product name: Trimeprazine hemi-(+)-tartrate salt
Packaging: 1g
Price: $239
Updated: 2025/07/31

Sigma-Aldrich

Product number: BP415
Product name: Alimemazine tartrate
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 100MG
Price: $268
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1689001
Product name: Trimeprazine tartrate
Packaging: 200mg
Price: $425
Updated: 2025/07/31

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Trimeprazine tartrate Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

Antipruritic. Antibacterial, antimicrobial agent

brand name

Temaril (Allergan).

General Description

Trimeprazine tartrate, (±)10-[3-(dimethylamino)-2-methylpropyl] phenothiazine tartrate(Temaril), occurs as a white to off-white crystalline powderthat is freely soluble in water and soluble in alcohol. Its antihistaminicaction is reported to be from 1.5 to 5 times thatof promethazine. Clinical studies have shown it has a pronouncedantipruritic action that may be unrelated to itshistamine-antagonizing properties.

in vivo

Alimemazine hemitartrate (10 mg/kg, intraperitoneal injection, once a day for 3 weeks) promotes mouse β-cell growth^[2].
Alimemazine hemitartrate (10 mg/kg, intraperitoneal injection, once a day for 22 days) synergistically reduces the progression of diabetes in NOD mice^[2].
Alimemazine hemitartrate (10 mg/kg, intraperitoneal injection, once a day for 7 days) promotes the proliferation and survival of β-cells in normal mice, but has little effect on β-cell defects caused by IRS2 deficiency^[2].
Alimemazine hemitartrate (10 mg/kg, oral gavage, two doses) does not reduce mouse lung virus titers^[3].

Animal Model:	Pdx1^+/– mice^[2]
Dosage:	10 mg/kg, once a day for 3 weeks
Administration:	Intraperitoneal injection (i.p.)
Result:	Increased HOMA 2%B and normalized glucose tolerance in mice.

Animal Model:	Irs2^-/–mice^[2]
Dosage:	10 mg/kg, once a day for seven days
Administration:	Intraperitoneal injection (i.p.)
Result:	Did not restore the function of β cells, but promoted β cell growth and increased the area of β cells in normal mice. Increased the concentration of IRS2 protein, had no effect on glucose tolerance in mice, and did not change the insulin sensitivity of mice.

Animal Model:	SARS-CoV-2 multiplication in mice^[3]
Dosage:	10mg/kg, at 1 h prior to and 24 h after virus inoculation
Administration:	i.g.
Result:	Did not reduce lung virus titers.

IC 50

GPCR

Trimeprazine tartrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Trimeprazine tartrate manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Trimeprazine tartrate 4330-99-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-02-17

Career Henan Chemical Co

Product: Trimeprazine tartrate 4330-99-8
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 200KG
Release date: 2020-01-07

4330-99-8, Trimeprazine tartrate Related Search:

Triethanolamine Metoprolol tartrate Tylosin tartrate L(+)-Tartaric acid Bis(2-ethylhexyl)amine L-Antimony potassium tartrate Trimeprazine Propane Kitasamycin tartrate D-Tartaric acid D(-)-Tartaric acid Triallylamine L-Carnitine-L-tartrate Zolpidem tartrate Butanedioic acid,2,3-dihydroxy- (2R,3R)-, ammonium salt (1:) Promazine Phenothiazine Sodium tartrate

10-(3-(dimethylamino)-2-methylpropyl)phenothiazinetartrate

10-(3-(dimethylamino)-2-methylpropyl)-phenothiazintartrate(2:1)

panectyl

repeltin

temaril

theralene

vallergan

n,n,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine tartrate

vanectyl

alimemazine tartrate

trimeprazine hemi-(+)tartrate

HydroxystilbamidineIsothionate

10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)

10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1)

NSC 17475

Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-, tartrate (2:1) (8CI)

Temaril 16

(3R,4R)-3,4-dihydroxyhexane-2,5-dione

TRIMEPRAZINE HEMI-(+)-TARTRATE SALT

TRIMEPRAZINE TARTRATE

TRIMEPRAZINE TARTRATE(R)(2:1)

Methylpromazine Tartrate

trimeprazine semitartrate

TriMeprazine HeMi-(+)-tartrate Salt, BP

Trimeprazine Tartrate (200 mg)

N,N,β-TriMethyl-

N,N,2-triMethyl-3-(10H-phenothiazin-10-yl)propan-1-aMine 2,3-dihydroxysuccinate

TriMeprazine Tartrate USP

Alimemazine for system suitability

Alimemazine hemitartrate

Alimernazine

Alimemazine Tartrate &gt

Alimemazine hemitartrate CRS

Trimeprazine tartrateQ: What is Trimeprazine tartrate Q: What is the CAS Number of Trimeprazine tartrate Q: What is the storage condition of Trimeprazine tartrate Q: What are the applications of Trimeprazine tartrate

Trimeprazine Tartrate (1689001)

Alimemazine Tartrate, ≥ 98.0%

Alimemazine hemitartrate, 10 mM in DMSO

Trimeprazine Tartrate 1.0 mg/ml in Methanol (as free base)

4330-99-8

C36H44N4S2C4H6O6

C20H25N2O3S

C40H50N4O6S2

C4H6O62C18H22N2S

C24H32N2O4S

2C18H22N2SC4H6O6

C18H22N2S2C4H6O6

C18H22N2S12C4H6O6

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