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ChemicalBook > CAS DataBase List > D-2-Phenylglycine

D-2-Phenylglycine

Description Storage
Product Name
D-2-Phenylglycine
CAS No.
875-74-1
Chemical Name
D-2-Phenylglycine
Synonyms
(R)-2-AMino-2-phenylacetic acid;D-PHENYLGLYCINE;D-(-)-PHENYLGLYCINE;H-D-PHG-OH;(2R)-2-amino-2-phenylacetic acid;ycine;D-Phg-OH;D-(-)-α-PhenyL;D-2-Phenylglyc;PHENYLGLYCINE-D
CBNumber
CB9413124
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
875-74-1.mol
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D-2-Phenylglycine Property

Melting point:
302 °C (dec.)(lit.)
alpha 
-156 º (c=1,1N HCl)
Boiling point:
273.17°C (rough estimate)
Density 
1.2 g/cm3 (20℃)
vapor pressure 
0Pa at 25℃
refractive index 
-158 ° (C=1, 1mol/L HCl)
Flash point:
150 °C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Acid (Sparingly), Water (Slightly, Heated)
pka
1.94±0.10(Predicted)
form 
Crystalline Powder
color 
White
optical activity
[α]20/D 155°, c = 1 in 1 M HCl
Water Solubility 
0.3g/100mL
Merck 
14,7291
BRN 
2208676
LogP
-1.76 at 20℃
CAS DataBase Reference
875-74-1(CAS DataBase Reference)
NIST Chemistry Reference
d a-Phenylglycine(875-74-1)
EPA Substance Registry System
Benzeneacetic acid, .alpha.-amino-, (.alpha.R)- (875-74-1)
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25-36/37/38-22-20
Safety Statements 
22-24/25-45-36/37/39-26-44-28-7-4
WGK Germany 
3
TSCA 
Yes
HS Code 
29224995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P25485
Product name
D?(?)-α-Phenylglycine
Purity
99%
Packaging
25g
Price
$40.7
Updated
2024/03/01
Sigma-Aldrich
Product number
P25485
Product name
D?(?)-α-Phenylglycine
Purity
99%
Packaging
100g
Price
$111
Updated
2024/03/01
TCI Chemical
Product number
P0820
Product name
D-2-Phenylglycine
Purity
>99.0%(T)
Packaging
25g
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
P0820
Product name
D-2-Phenylglycine
Purity
>99.0%(T)
Packaging
100g
Price
$54
Updated
2024/03/01
Alfa Aesar
Product number
A15669
Product name
D-(-)-2-Phenylglycine, 99%
Packaging
25g
Price
$24.65
Updated
2024/03/01
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D-2-Phenylglycine Chemical Properties,Usage,Production

Description

L-phenylglycine (Cephalexin EP Impurity A) is a derivative of glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in the spinal cord and an allosteric modulator of NMDA receptors.

Storage

Store at room temperature. Store in cool dry place in tightly closed container. Store away from oxidizing agent.

Description

d-Phenylglycine is widely used in large quantity as the side chain that makes ampicillin and cephalexin orally acceptable.

Chemical Properties

White crystalline powder

Uses

D-(-)-2-Phenylglycine (Cefalexin EP Impurity A) is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Uses

D-(-)-2-Phenylglycine is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA r eceptors.

Definition

ChEBI: The R stereoisomer of alpha-phenylglycine.

Flammability and Explosibility

Non flammable

Synthesis

Industrially, dphenylglycine has been produced by a conventional resolution method or by kinetic resolution with acylase. Another enzymatic procedure has been developed by Yamada et al. , as shown below.

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View Lastest Price from D-2-Phenylglycine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
H-D-Phg-OH 875-74-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1T+
Release date
2023-09-23
Shanghai UCHEM Inc.
Product
D-2-Phenylglycine 875-74-1
Price
US $56.00/kg
Min. Order
1kg
Purity
0.98
Supply Ability
100kg
Release date
2024-01-10
WUHAN FORTUNA CHEMICAL CO., LTD
Product
D-2-Phenylglycine 875-74-1
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kgs
Release date
2021-09-28

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