4-Aminodiphenylamine Property

Melting point:

69 °C

Boiling point:

354 °C

Density 

1.09

vapor pressure 

1 hPa

refractive index 

1.6266 (estimate)

Flash point:

193°C

storage temp. 

Store below +30°C.

solubility 

ethanol: soluble10mg/mL, clear, very dark red (Violet to brown to black solution)

pka

5.20±0.10(Predicted)

form 

Liquid

Colour Index 

37240

color 

Clear

PH

8.9 (0.5g/l, H2O, 20℃)

Water Solubility 

Soluble in water at 20°C 0.6g/L. Soluble in (10 mg/mL) ethanol.

BRN 

908935

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, plastics.

LogP

1.82 at 20℃ and pH7

Dissociation constant

5.45-5.47 at 20℃

CAS DataBase Reference

101-54-2(CAS DataBase Reference)

NIST Chemistry Reference

1,4-Benzenediamine, N-phenyl-(101-54-2)

EPA Substance Registry System

p-Aminodiphenylamine (101-54-2)

Safety

Hazard Codes 

Xn,Xi,N

Risk Statements 

22-36-43-42/43-36/37/38-20/22-50/53

Safety Statements 

26-36-45-36/37/39-61-60-36/37

RIDADR 

UN3077

WGK Germany 

3

RTECS 

ST3150000

F 

8

Autoignition Temperature

>500 °C

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

9

PackingGroup 

III

HS Code 

29215990

Hazardous Substances Data

101-54-2(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 464 mg/kg LD50 dermal Rabbit > 5000 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

4-Aminodiphenylamine Chemical Properties,Usage,Production

Description

p-Aminodiphenylamine hydrochloride was formerly used as a hair dye. Sensitization, when deteeted by patch testing, is relatively low in hairdressers.

Chemical Properties

Dark grey flake

Uses

Dye intermediate, pharmaceuticals, photographic chemicals.

Uses

4-Aminodiphenylamine is used as an oxidation dye color in hair dyes. It is also promoted as an efficient reagent for oxidase enzymes, including glucose, lactate, xanthine, and lysine oxidases.

Uses

p-Anilinoaniline is an antioxidant that has shown to cause a reduction of NOx emissions from soybean biodiesel powered DI diesel engines but has increased CO and HC emissions. It is also used to produce dyes, pharmaceuticals, and photographic chemicals and frmerly used as a hair dye.

Definition

ChEBI: An aromatic amine that is the 4-amino derivative of diphenylamine.

General Description

Odorless purple-black solid or flake or dark purple chips.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4-Aminodiphenylamine is incompatible with strong oxidizers. 4-Aminodiphenylamine is also incompatible with strong acids. 4-Aminodiphenylamine may react with plastics.

Fire Hazard

4-Aminodiphenylamine is combustible.

Contact allergens

This substance was formerly used as a hair dye. Sensitization, when detected by patch testing, is relatively low in hairdressers.

Purification Methods

It crystallises from EtOH with m 66o, and from ligroin with m 75o. It can be distilled at high vacuum. [Beilstein 13 IV 113.]