OLEYLHYDROXAMIC ACID

Product Name: OLEYLHYDROXAMIC ACID
CAS No.: 10335-69-0
Chemical Name: OLEYLHYDROXAMIC ACID
Synonyms: Einecs 233-728-4;N-hydroxyoleamide;N-Hydroxyoleylamide;N-Hydroxyoleic amide;OLEYLHYDROXAMIC ACID;Oleoylhydroxamic acid;N-Hydroxy-9-octadecenamide;(Z)-N-Hydroxy-9-octadecenamide;(9Z)-9-Octadecenehydroxamic acid;9-Octadecenamide, N-hydroxy-, (9Z)-
CBNumber: CB9421385
Molecular Formula: C18H35NO2
Formula Weight: 297.48
MOL File: 10335-69-0.mol

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OLEYLHYDROXAMIC ACID Property

Melting point:: 61 °C
Density: 0.921±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: ≤50mg/ml in ethanol;50mg/ml in DMSO;50mg/ml in dimethyl formamide
form: crystalline solid
pka: 9.48±0.20(Predicted)
color: White to off-white
InChI: 1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(20)19-21/h9-10,21H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
InChIKey: LTXHELLMCCEDJG-KTKRTIGZSA-N
SMILES: N(O)C(=O)CCCCCCC\C=C/CCCCCCCC
EPA Substance Registry System: N-Hydroxyoleylamide (10335-69-0)

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Safety

WGK Germany: WGK 1
TSCA: TSCA listed
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 444244
Product name: MMP-2 Inhibitor I
Purity: The MMP-2 Inhibitor I, also referenced under CAS 10335-69-0, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Packaging: 10mg
Price: $130
Updated: 2026/03/19

Cayman Chemical

Product number: 19644
Product name: MMP-2 Inhibitor I
Purity: ≥98%
Packaging: 5mg
Price: $65
Updated: 2024/03/01

Cayman Chemical

Product number: 19644
Product name: MMP-2 Inhibitor I
Purity: ≥98%
Packaging: 10mg
Price: $96
Updated: 2024/03/01

ApexBio Technology

Product number: C5615
Product name: MMP-2InhibitorI
Packaging: 10mg
Price: $108
Updated: 2021/12/16

ApexBio Technology

Product number: C5615
Product name: MMP-2InhibitorI
Packaging: 5mg
Price: $71
Updated: 2021/12/16

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OLEYLHYDROXAMIC ACID Chemical Properties,Usage,Production

Uses

MMP-2 Inhibitor I (OA-Hy) is a potent MMP-2 inhibitor with a Ki of 1.7 μM[1].

Biological Activity

mmp-2 inhibitor i, a hydroxamate-based, long-chain fatty acid, is a reversible inhibitor of matrix metalloproteinase (mmp)-2.matrix metalloproteinases (mmps) have been involved in the degradation of extracellular matrix. mmps contribute to long-term remodeling processes such as embryogenesis, tumor invasion, inflammation, angiogenesis, and wound healing. mmp-2, also known as gelatinase a or type iv collagenase, has been involved in regulating diverse cellular functions independent of its action on the extracellular matrix, including vascular tone, platelet aggregation, and mediation of the acute mechanical dysfunction of the heart immediately after ischemia and reperfusion [2]. up-regulation of mmp-2 has been associated with tumor invasion and metastasis [3].mmp-2 inhibitor i inhibited the activity of matrix metalloproteinase (mmp)-2 with the ki value of 1.6 μm [1]. mmp-2 inhibitor i attenuated cancer cell migration [3]. mmp-2 inhibitor i had also been used to preserve blood-brain barrier function in a wistar rat model of pneumococcal meningitis [4].

IC 50

MMP-2: 1.7 μM (Ki)

References

[1] berton a, rigot v, huet e, et al. involvement of fibronectin type ii repeats in the efficient inhibition of gelatinases a and b by long-chain unsaturated fatty acids[j]. journal of biological chemistry, 2001, 276(23): 20458-20465.
[2] wang w, schulze c j, suarez-pinzon w l, et al. intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury[j]. circulation, 2002, 106(12): 1543-1549.
[3] emmert-buck m r, roth m j, zhuang z, et al. increased gelatinase a (mmp-2) and cathepsin b activity in invasive tumor regions of human colon cancer samples[j]. the american journal of pathology, 1994, 145(6): 1285.
[4] barichello t, generoso j s, michelon c m, et al. inhibition of matrix metalloproteinases-2 and-9 prevents cognitive impairment induced by pneumococcal meningitis in wistar rats[j]. experimental biology and medicine, 2014, 239(2): 225-231.

OLEYLHYDROXAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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OLEYLHYDROXAMIC ACID Suppliers

China 14 Germany 1 South Korea 1 United States 4 Global 20

SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD

Tel: 13816107857
Fax: qq: 276312098
Email: sales@fortunechem-sh.com
Country: China
ProdList: 984
Advantage: 58

Changzhou Chenhong Biotechnology Co., Ltd.

Tel: +86-0519-85788828 +86-13775037613
Email: sales@chemrenpharm.com
Country: China
ProdList: 4032
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Tianmen Hengchang Chemical Co., Ltd

Tel: 027-59322316 15172518801
Fax: 027-59322316
Email: 1018286633@qq.com
Country: China
ProdList: 9531
Advantage: 58

Hubei Qifei Pharmaceutical Chemical Co., Ltd

Tel: 027-59322506 18071128681
Fax: 027-59322506
Email: 1438082200@qq.com
Country: China
ProdList: 9601
Advantage: 58

Shaanxi Dideu Newmaterial Co., Ltd.

Tel: 029-029-63373950 17392216152
Email: 1050@dideu.com
Country: China
ProdList: 9998
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11972
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6038
Advantage: 58

10335-69-0, OLEYLHYDROXAMIC ACIDRelated Search:

HEXANOHYDROXAMIC ACID (E)-9-octadecenamide OLEYLHYDROXAMIC ACID Oleamide Heptanamide, N-hydroxy- CAPRYLOHYDROXAMIC ACID

OLEYLHYDROXAMIC ACID

N-hydroxyoleamide

(9Z)-9-Octadecenehydroxamic acid

(Z)-N-Hydroxy-9-octadecenamide

Hydroxamate derivative of oleic acid

N-Hydroxyoleic amide

Oleoylhydroxamic acid

9-Octadecenamide, N-hydroxy-, (9Z)-

Einecs 233-728-4

N-Hydroxy-9-octadecenamide

N-Hydroxyoleylamide

10335-69-0