2-BROMO-4-NITROANILINE
- Product Name
- 2-BROMO-4-NITROANILINE
- CAS No.
- 13296-94-1
- Chemical Name
- 2-BROMO-4-NITROANILINE
- Synonyms
- AKOS BBB/074;BUTTPARK 147\16-92;TIMTEC-BB SBB007590;2-Brom-4-nitroanilin;2-bromo-4-nitro-anilin;2-BROMO-4-NITROANILINE;6-Bromo-p-nitroaniline;Aniline, 2-bromo-4-nitro-;2-Bromo-4-nitrobenzenamine;2-BROMO-4-NITRO-PHENYLAMINE
- CBNumber
- CB9422322
- Molecular Formula
- C6H5BrN2O2
- Formula Weight
- 217.02
- MOL File
- 13296-94-1.mol
2-BROMO-4-NITROANILINE Property
- Melting point:
- 104°C
- Boiling point:
- 351.8±22.0 °C(Predicted)
- Density
- 1.7917 (rough estimate)
- refractive index
- 1.5150 (estimate)
- Flash point:
- 166℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- -1.18±0.10(Predicted)
- color
- Dark Yellow
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 13296-94-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenamine, 2-bromo-4-nitro-(13296-94-1)
- EPA Substance Registry System
- 2-Bromo-4-nitroaniline (13296-94-1)
Safety
- Hazard Codes
- T,Xi
- Risk Statements
- 23/24/25-33
- Safety Statements
- 28-37-45
- RTECS
- BW9350000
- HazardClass
- IRRITANT
- HS Code
- 29214200
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B4873
- Product name
- 2-Bromo-4-nitroaniline
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $42
- Updated
- 2025/07/31
- Product number
- B4873
- Product name
- 2-Bromo-4-nitroaniline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $130
- Updated
- 2025/07/31
- Product number
- B687655
- Product name
- 2-Bromo-4-nitroaniline
- Packaging
- 10g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- FB00916
- Product name
- 2-Bromo-4-nitroaniline
- Packaging
- 250g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- CS-W005164
- Product name
- 2-Bromo-4-nitroaniline
- Purity
- 99.34%
- Packaging
- 100g
- Price
- $148
- Updated
- 2021/12/16
2-BROMO-4-NITROANILINE Chemical Properties,Usage,Production
Chemical Properties
Yellow solid
Uses
2-Bromo-4-nitroaniline is used as a reagent in the synthesis of novel tetrahydrothienopyridopyrimidine derivatives which exhibit antibacterial and antifungal activity against a variety of microorganisms in vitro. Also used as a reagent in synthesis of dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14α-demethylase as anti-Chagas disease agents.
Synthesis
100-01-6
13296-94-1
Bromine (2.05 mL, 40 mmol) was slowly added dropwise to a solution of 4-nitroaniline (5.0 g, 36 mmol) in acetic acid (150 mL) at room temperature and under argon protection. The reaction mixture was stirred continuously for 2 hours at room temperature. Upon completion of the reaction, the reaction was quenched with dilute aqueous sodium thiosulfate (150 mL) followed by extraction with ethyl acetate (2 x 500 mL). The organic layers were combined and carefully poured into saturated aqueous sodium bicarbonate solution (1 L) and stirred at room temperature for 30 min until the gas release stopped completely. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by column chromatography (petroleum ether/dichloromethane, 3:1) to afford 2-bromo-4-nitroaniline as a yellow solid (6.3 g, 80% yield).1H NMR (400 MHz, CDCl3) δ: 8.39 (1H, d, J = 2.4 Hz), 8.06 (1H, d, J = 2.4 Hz), 6.77 (1H, d, J = 9.2 Hz).
References
[1] Synthesis, 2004, # 17, p. 2809 - 2812
[2] Tetrahedron Letters, 2017, vol. 58, # 48, p. 4559 - 4562
[3] Tetrahedron Letters, 2005, vol. 46, # 51, p. 8959 - 8963
[4] Synthetic Communications, 2010, vol. 40, # 21, p. 3226 - 3232
[5] Journal of the American Chemical Society, 1994, vol. 116, # 26, p. 11797 - 11810
2-BROMO-4-NITROANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-BROMO-4-NITROANILINE Suppliers
- Tel
- --
- Fax
- --
- info@specs.net
- Country
- The Netherlands
- ProdList
- 6833
- Advantage
- 70
View Lastest Price from 2-BROMO-4-NITROANILINE manufacturers
- Product
- 2-BROMO-4-NITROANILINE 13296-94-1
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25
- Product
- 2-Bromo-4-nitroaniline 13296-94-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.9%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 2-Bromo-4-nitroaniline 13296-94-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100 tons
- Release date
- 2020-01-10