5-NITROINDOLE-3-CARBOXYLIC ACID

Product Name: 5-NITROINDOLE-3-CARBOXYLIC ACID
CAS No.: 6958-37-8
Chemical Name: 5-NITROINDOLE-3-CARBOXYLIC ACID
Synonyms: RARECHEM AL BE 1168;5-NITROINDOLE-3-CARBOXYLIC ACID;5-nitro-1H-indole-3-carboxylic acid;1H-Indole-3-carboxylic acid, 5-nitro-
CBNumber: CB9435674
Molecular Formula: C9H6N2O4
Formula Weight: 206.15
MOL File: 6958-37-8.mol

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5-NITROINDOLE-3-CARBOXYLIC ACID Property

Melting point:: 276-278 °C (decomp)
Boiling point:: 520.8±30.0 °C(Predicted)
Density: 1.632±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 3.38±0.30(Predicted)
Appearance: Light brown to brown Solid
InChI: InChI=1S/C9H6N2O4/c12-9(13)7-4-10-8-2-1-5(11(14)15)3-6(7)8/h1-4,10H,(H,12,13)
InChIKey: OOOJXNVTVWRZMA-UHFFFAOYSA-N
SMILES: N1C2=C(C=C([N+]([O-])=O)C=C2)C(C(O)=O)=C1
CAS DataBase Reference: 6958-37-8(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: N901350
Product name: 5-Nitro-1H-indole-3-carboxylicAcid
Packaging: 100mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: 0747AC
Product name: 5-Nitro-1H-indole-3-carboxylicacid
Packaging: 5g
Price: $551
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0027460
Product name: 5-NITROINDOLE-3-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 1G
Price: $736.12
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0027460
Product name: 5-NITROINDOLE-3-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 2.5G
Price: $1011.6
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0027460
Product name: 5-NITROINDOLE-3-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 5G
Price: $1210.63
Updated: 2021/12/16

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5-NITROINDOLE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis Reference(s)

Journal of Medicinal Chemistry, 35, p. 1019, 1992 DOI: 10.1021/jm00084a007

Synthesis

101832-10-4

6958-37-8

1-(5-nitro-3-indolyl)-2,2,2-trifluoroethanone (7 g, 24.7 mmol) was used as the raw material, which was dissolved in 40% aqueous NaOH solution (40 mL), and the reaction was stirred for 3 hours at 60 °C. After completion of the reaction, the reaction mixture was cooled to 0 °C and acidified by slowly adding 1N HCl aqueous solution to adjust the pH to ~3. Subsequently, the precipitate was collected by filtration, the filter cake was washed with water, and finally the target product 5-nitroindole-3-carboxylic acid (5.9 g, 100% yield) was obtained by concentration as a brown solid. The product was detected by LC/MS (ESI), m/z: 207 [M + 1]+.

References

[1] Patent: WO2017/35351, 2017, A1. Location in patent: Paragraph 0584; 0585; 0586
[2] Russian Journal of General Chemistry, 2017, vol. 87, # 12, p. 3006 - 3016

5-NITROINDOLE-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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5-NITROINDOLE-3-CARBOXYLIC ACID Suppliers

China 63 Germany 1 India 1 Switzerland 1 United Kingdom 6 United States 17 Global 89

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View Lastest Price from 5-NITROINDOLE-3-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co

Product: 5-nitro-1H-indole-3-carboxylic acid 6958-37-8
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2020-01-09

6958-37-8, 5-NITROINDOLE-3-CARBOXYLIC ACIDRelated Search:

3-CYANO-5-NITROINDOLE 5-Nitro-1H-indole-3-carbaldehyde 4-NITROINDOLE-3-CARBOXYLIC ACID 5-NITROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 5-NITROINDOLE-3-CARBOXYLIC ACID 7-NITROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 5-NITROINDOLE-2-CARBOXYLIC ACID 7-NITROINDOLE-2-CARBOXYLIC ACID,7-Nitroindole-2-carboxylic acid, 90-95% 5-Nitroindole 4-NITROINDOLE-2-CARBOXYLIC ACID 3-HYDROXYMETHYL-5-NITROINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 7-METHOXY-5-NITROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 6-NITROINDOLE-3-CARBOXYLIC ACID 3-BROMO-5-NITROINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 3-FORMYL-5-NITROINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 3-IODO-5-NITROINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 6-NITROINDOLE-2-CARBOXYLIC ACID 3-BROMO-7-NITROINDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

RARECHEM AL BE 1168

5-NITROINDOLE-3-CARBOXYLIC ACID

5-nitro-1H-indole-3-carboxylic acid

1H-Indole-3-carboxylic acid, 5-nitro-

6958-37-8

C9H6N2O4

Indole