ChemicalBook > CAS DataBase List > 6-AMINO-3H-QUINAZOLIN-4-ONE

6-AMINO-3H-QUINAZOLIN-4-ONE

Product Name
6-AMINO-3H-QUINAZOLIN-4-ONE
CAS No.
17329-31-6
Chemical Name
6-AMINO-3H-QUINAZOLIN-4-ONE
Synonyms
6-aMino-2,3-dihydroquinazolin-4(1H)-one;6-Amino-4-quinazolinol;6-aminoquinazolin-4-ol;6-AMINO-4-QUINAZOLINONE;6-AMinoquinazolin-4-one;ASINEX-REAG BAS 10150436;6-AMINO-3H-QUINAZOLIN-4-ONE;6-amino-4(3h)-quinazolinone;6-AMINO-4(1H)-QUINAZOLINONE;6-amino-1H-quinazolin-4-one
CBNumber
CB9438312
Molecular Formula
C8H7N3O
Formula Weight
161.16
MOL File
17329-31-6.mol
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6-AMINO-3H-QUINAZOLIN-4-ONE Property

Melting point:
303 °C(Solv: water (7732-18-5))
Boiling point:
421.1±47.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
3.95±0.20(Predicted)
Appearance
Light yellow to yellow Solid
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A630708
Product name
6-Amino-3H-quinazolin-4-one
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA131313
Product name
6-Aminoquinazolin-4(3H)-one
Packaging
250mg
Price
$85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA131313
Product name
6-Aminoquinazolin-4(3H)-one
Packaging
500mg
Price
$150
Updated
2021/12/16
Matrix Scientific
Product number
020665
Product name
6-Amino-3H-quinazolin-4-one
Packaging
500mg
Price
$155
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA131313
Product name
6-Aminoquinazolin-4(3H)-one
Packaging
1g
Price
$255
Updated
2021/12/16
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6-AMINO-3H-QUINAZOLIN-4-ONE Chemical Properties,Usage,Production

Synthesis

6943-17-5

17329-31-6

General procedure for the synthesis of 6-amino-3H-quinazolin-4-one from 4-hydroxy-6-nitroquinazoline: a methanol (500 ml) solution of intermediate 5A (1 g, 5.23 mmol) was added to a 1 L three-necked flask to form a yellow suspension. Subsequently 10% palladium/carbon catalyst (0.056 g, 0.523 mmol) was added. The reaction mixture was stirred at room temperature and reacted for 4 hours under hydrogen balloon atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to give 0.84 g of yellow solid product (100% yield). The structure of the product was confirmed by 1H NMR (500 MHz, DMSO-d6) with chemical shifts δppm of 5.60 (s, 2H), 7.05 (dd, J = 8.80,2.75Hz, 1H), 7.16 (d, J = 2.75Hz, 1H), 7.36 (d, J = 8.80Hz, 1H), 7.74 (s, 1H ) and 11.80 (s, 1H).

References

[1] Patent: WO2008/79759, 2008, A1. Location in patent: Page/Page column 90
[2] Patent: WO2008/79836, 2008, A2. Location in patent: Page/Page column 86
[3] Tetrahedron Letters, 2003, vol. 44, # 24, p. 4455 - 4458
[4] European Journal of Medicinal Chemistry, 2012, vol. 50, p. 264 - 273
[5] Chemical and Pharmaceutical Bulletin, 2014, vol. 62, # 12, p. 1166 - 1172

6-AMINO-3H-QUINAZOLIN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-AMINO-3H-QUINAZOLIN-4-ONE Suppliers

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View Lastest Price from 6-AMINO-3H-QUINAZOLIN-4-ONE manufacturers

Career Henan Chemical Co
Product
6-AMINO-3H-QUINAZOLIN-4-ONE 17329-31-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,100kg
Release date
2019-07-04

17329-31-6, 6-AMINO-3H-QUINAZOLIN-4-ONERelated Search:

Afloqualone 6-NITROQUINAZOLIN-4(3H)-ONE (4-OXO-6-PIPERAZIN-1-YL-4H-QUINAZOLIN-3-YL)-ACETIC ACID 6-AMINO-3H-QUINAZOLIN-4-ONE 2,4-DIHYDROXY-6-NITROQUINAZOLINE 7-Fluoro-6-nitro-4-hydroxyquinazoline 2-AMINO-3H-QUINAZOLIN-4-ONE 4-Hydroxyquinazoline 2-AMINO-6-NITRO-4(3H)-QUINAZOLONE 6-AMINO-2-PHENYL-QUINAZOLIN-4-OL 6-(N-FMOC-PIPERAZIN-1-YL)-4(3H)-QUINAZOLINONE-3-ACETIC ACID 2-[(3,4-DICHLOROPHENYL)AMINO]-1,4-DIHYDRO-6-NITRO-4-OXO-N-2-PROPENYL-8-QUINAZOLINECARBOXAMIDE 6-AMINO-2-METHYL-QUINAZOLIN-4-OL 2,6-DIAMINO-4-HYDROXYQUINAZOLINE 6-AMINO-2-TRIFLUOROMETHYL-QUINAZOLIN-4-OL 6-Nitro-7-Chloro-4-HydroxyQuinazoline 2-amino-11H-pyrido(2,1-b)quinazolin-11-one 2-(4-METHYLPHENYL)-6-(1-PYRROLIDINYL)-4(3H)-QUINAZOLINONE

  • ASINEX-REAG BAS 10150436
  • 6-amino-4(3h)-quinazolinone
  • 6-AMINO-3H-QUINAZOLIN-4-ONE
  • 6-AMINO-4-HYDROXYQUINAZOLINE
  • 6-AMINO-4(1H)-QUINAZOLINONE
  • 6-AMINO-4-QUINAZOLINONE
  • 6-Amino-3H-quinazoline-4-one
  • 6-Amino-3H-quinazolin-4-one 6-Amino-4-quinazolinone
  • 6-AMinoquinazolin-4-one
  • 6-aMino-3,4-dihydroquinazolin-4-one
  • 6-aMino-2,3-dihydroquinazolin-4(1H)-one
  • 6-amino-1H-quinazolin-4-one
  • 6-Amino-4-quinazolinol
  • 4(3H)-Quinazolinone, 6-amino-
  • 6-aminoquinazolin-4-ol
  • 17329-31-6
  • pharmacetical
  • API intermediates