2,4-Dimethoxybenzyl alcohol
- Product Name
- 2,4-Dimethoxybenzyl alcohol
- CAS No.
- 7314-44-5
- Chemical Name
- 2,4-Dimethoxybenzyl alcohol
- Synonyms
- (2,4-DIMETHOXYPHENYL)METHANOL;2,4-Dimethoxybenzyl;AI3-52354;RARECHEM AL BD 0025;2,4-DIMETHOXYBENZYL ALCOHOL;2,4-Dimethoxybenzenemethanol;Benzenemethanol, 2,4-dimethoxy-;2,4-Dimethoxybenzyl alcohol 99%;2,4-Dimethoxybenzyl alcohol,99%;2,4-Dimethoxybenzyl Alcohol >
- CBNumber
- CB9462748
- Molecular Formula
- C9H12O3
- Formula Weight
- 168.19
- MOL File
- 7314-44-5.mol
2,4-Dimethoxybenzyl alcohol Property
- Melting point:
- 38-40 °C(lit.)
- Boiling point:
- 177-179 °C10 mm Hg(lit.)
- Density
- 1.1322 (rough estimate)
- refractive index
- 1.545-1.548
- Flash point:
- >230 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 14.18±0.10(Predicted)
- form
- Low Melting Solid
- color
- Colourless to Off-White
- Water Solubility
- Soluble in alcohol. Insoluble in water.
- BRN
- 2091660
- LogP
- 1.109 (est)
- CAS DataBase Reference
- 7314-44-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 2,4-Dimethoxybenzyl alcohol(7314-44-5)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-36/37-26
- WGK Germany
- 3
- HS Code
- 29062990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 159638
- Product name
- 2,4-Dimethoxybenzyl alcohol
- Purity
- 99%
- Packaging
- 25g
- Price
- $148
- Updated
- 2025/07/31
- Product number
- 159638
- Product name
- 2,4-Dimethoxybenzyl alcohol
- Purity
- 99%
- Packaging
- 100g
- Price
- $228.9
- Updated
- 2025/07/31
- Product number
- D1835
- Product name
- 2,4-Dimethoxybenzyl Alcohol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $26
- Updated
- 2025/07/31
- Product number
- D1835
- Product name
- 2,4-Dimethoxybenzyl Alcohol
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $123
- Updated
- 2025/07/31
- Product number
- D460115
- Product name
- 2,4-Dimethoxybenzyl alcohol
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
2,4-Dimethoxybenzyl alcohol Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow liqui
Uses
2, 4-Dimethoxybenzyl alcohol is used as a medical intermediate.
General Description
2,4-Dimethoxybenzyl alcohol reacts with trifluoroacetic acid to yield calix[4]resorcinarene octamethyl ether, which on demethylation and acetylation yields the derived octa-acetate.
Synthesis
613-45-6
7314-44-5
The general procedure for the synthesis of 2,4-dimethoxybenzyl alcohol from 2,4-dimethoxybenzaldehyde was as follows: to an oven-dried pressure tube equipped with a Teflon-coated stirring bar were added sequentially Pd(OAc)2 (11.2 mg, 5 mol%), PCy3 (21 mg, 7.5 mol%) and 2,4-dimethoxybenzaldehyde (1 mmol). The reaction tube was sealed, evacuated and backfilled three times with nitrogen. Subsequently, 1 mL of dioxane was injected and the mixture was stirred at room temperature for 15 min. H2O (180 mg, 10 eq.) and HCO2H (184 mg, 4 eq.) were then injected and the reaction mixture was heated to 90 °C and kept for 18 hours. After completion of the reaction, the solvent was removed under reduced pressure. The residue was purified by silica gel fast column chromatography to afford 87 mg of 2,4-dimethoxybenzyl alcohol in 81% yield.
References
[1] Synthetic Communications, 2001, vol. 31, # 17, p. 2719 - 2725
[2] Organic Letters, 2015, vol. 17, # 3, p. 434 - 437
[3] Tetrahedron Letters, 1992, vol. 33, # 37, p. 5417 - 5418
[4] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1994, vol. 33, # 2, p. 182 - 183
[5] Tetrahedron Letters, 1994, vol. 35, # 1, p. 65 - 68
2,4-Dimethoxybenzyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-Dimethoxybenzyl alcohol Suppliers
- Tel
- --
- Fax
- --
- chemcontrol@nextra.sk
- Country
- Slovakia
- ProdList
- 6700
- Advantage
- 60
View Lastest Price from 2,4-Dimethoxybenzyl alcohol manufacturers
- Product
- 2,4-Dimethoxybenzyl alcohol 7314-44-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-09
- Product
- 2,4-Dimethoxybenzyl alcohol 7314-44-5
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10TON
- Release date
- 2018-12-18