ChemicalBook > CAS DataBase List > TFLLR-NH2

TFLLR-NH2

Product Name: TFLLR-NH2
CAS No.: 197794-83-5
Chemical Name: TFLLR-NH2
Synonyms: TFLLR;TFLLR-NH2;TFLLR-AMIDE;TFLLR-NH2(2TFA);(Thr1)-TRAP-5 amide;HYBRIDE HUMAN-XENOPE;PAR-1 agonist/ TRAP6;THR-PHE-LEU-LEU-ARG-NH2;1313730-19-6/197794-83-5;H-THR-PHE-LEU-LEU-ARG-NH2
CBNumber: CB9464681
Molecular Formula: C31H53N9O6
Formula Weight: 647.81
MOL File: 197794-83-5.mol

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TFLLR-NH2 Property

Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Desiccate at -20°C
pka: 12.10±0.45(Predicted)
form: Powder
Water Solubility: Soluble to 1 mg/ml in water
Sequence: Thr-Phe-Leu-Leu-Arg-NH2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1464
Product name: TFLLR-NH2
Packaging: 1
Price: $312
Updated: 2021/12/16

TRC

Product number: T966355
Product name: TFLLR-NH2
Packaging: 1mg
Price: $280
Updated: 2021/12/16

Usbiological

Product number: 256912
Product name: TFLLR-NH2
Packaging: 1mg
Price: $573
Updated: 2021/12/16

ApexBio Technology

Product number: A8666
Product name: TFLLR-NH2
Packaging: 1mg
Price: $288
Updated: 2021/12/16

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TFLLR-NH2 Chemical Properties,Usage,Production

Uses

TFLLR-NH2 is a PAR-1 activator.

in vivo

Injection of TF-NH2 into the rat paw stimulates a marked and sustained oedema. An NK1R antagonist and ablation of sensory nerves with capsaicin inhibit oedema by 44% at 1?h and completely by 5?h. In wild-type but not PAR1^?/? mice, TF-NH2 stimulates Evans blue extravasation in the bladder, oesophagus, stomach, intestine and pancreas by 2–8 fold. Extravasation in the bladder, oesophagus and stomach is abolished by an NK1R antagonist^[1]. TFp-NH2 produces notable contraction at 3-50 μM and relaxation at 0.3-50 μM, in the absence of apamin. The concentration-response curve for TFp-NH2-induced contraction is remarkably shifted left, when the TFp-NH2-induced relaxation is blocked by apamin at 0.1 μM^[3].

IC 50

PAR1: 1.9 μM (EC₅₀)

storage

-20°C

TFLLR-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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TFLLR-NH2 Suppliers

China 80 Europe 1 France 1 Germany 3 United Kingdom 2 United States 13 Global 100

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View Lastest Price from TFLLR-NH2 manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: TFLLR-NH2 197794-83-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

Career Henan Chemical Co

Product: TFLLR-NH2 197794-83-5
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-13

197794-83-5, TFLLR-NH2Related Search:

DL-Threonine hydrate(2:1) ANTI HUMAN TR-ALPHA Trifluoroacetamide H-SER-PHE-LEU-LEU-ARG-NH2 TFLLR-NH2 H-THR-PHE-LEU-LEU-ARG-NH2 TRIFLUOROACETATE SALT THR-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-NH2

H-THR-PHE-LEU-LEU-ARG-NH2

THR-PHE-LEU-LEU-ARG-NH2

THROMBIN RECEPTOR (PAR-1), HYBRIDE HUMAN-XENOPE

TFLLR-AMIDE

TFLLR-NH2

(Thr1)-TRAP-5 amide

TFLLR-NH2 Protease-Activated Receptor 1 (PAR1) Agonist

(2S)-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide

TFLLR-NH2(2TFA)

TFLLRaMide, (Thr1)-TRAP-5 aMide, (Thr1)-PAR-1 (1-5) aMide (huMan)

HYBRIDE HUMAN-XENOPE

TFLLR

REF DUPL: H-Thr-Phe-Leu-Leu-Arg-NH2

(Thr1)-PAR-1 (1-5) amide (human)

L-Argininamide, L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-

TFLLR-NH2 2TFA(197794-83-5(free base))

TFLLR NH2 2TFA(197794 83 5(free base)),TFLLR-NH-2 2TFA(197794-83-5(free base)),TFLLRNH2 2TFA(197794835(free base))

1313730-19-6/197794-83-5

(Thr?)-PAR-1 (1-5) amide (human) trifluoroacetate salt

TFLLR-NH2, PAR1 agonist peptide

PAR-1 agonist/ TRAP6

197794-83-5

C31H53N9O6

C35H55F6N9O10

Proteinase-activated receptor (PAR)

Peptide Receptors