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TFLLR-NH2

Product Name
TFLLR-NH2
CAS No.
197794-83-5
Chemical Name
TFLLR-NH2
Synonyms
TFLLR;TFLLR-NH2;TFLLR-AMIDE;TFLLR-NH2(2TFA);(Thr1)-TRAP-5 amide;HYBRIDE HUMAN-XENOPE;PAR-1 agonist/ TRAP6;THR-PHE-LEU-LEU-ARG-NH2;1313730-19-6/197794-83-5;H-THR-PHE-LEU-LEU-ARG-NH2
CBNumber
CB9464681
Molecular Formula
C31H53N9O6
Formula Weight
647.81
MOL File
197794-83-5.mol
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TFLLR-NH2 Property

Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at -20°C
pka
12.10±0.45(Predicted)
form 
Powder
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
Thr-Phe-Leu-Leu-Arg-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1464
Product name
TFLLR-NH2
Packaging
1
Price
$312
Updated
2021/12/16
TRC
Product number
T966355
Product name
TFLLR-NH2
Packaging
1mg
Price
$280
Updated
2021/12/16
Usbiological
Product number
256912
Product name
TFLLR-NH2
Packaging
1mg
Price
$573
Updated
2021/12/16
ApexBio Technology
Product number
A8666
Product name
TFLLR-NH2
Packaging
1mg
Price
$288
Updated
2021/12/16
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TFLLR-NH2 Chemical Properties,Usage,Production

Uses

TFLLR-NH2 is a PAR-1 activator.

in vivo

Injection of TF-NH2 into the rat paw stimulates a marked and sustained oedema. An NK1R antagonist and ablation of sensory nerves with capsaicin inhibit oedema by 44% at 1?h and completely by 5?h. In wild-type but not PAR1?/? mice, TF-NH2 stimulates Evans blue extravasation in the bladder, oesophagus, stomach, intestine and pancreas by 2–8 fold. Extravasation in the bladder, oesophagus and stomach is abolished by an NK1R antagonist[1]. TFp-NH2 produces notable contraction at 3-50 μM and relaxation at 0.3-50 μM, in the absence of apamin. The concentration-response curve for TFp-NH2-induced contraction is remarkably shifted left, when the TFp-NH2-induced relaxation is blocked by apamin at 0.1 μM[3].

IC 50

PAR1: 1.9 μM (EC50)

storage

-20°C

TFLLR-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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TFLLR-NH2 Suppliers

China 80 Europe 1 France 1 Germany 3 United Kingdom 2 United States 13 Global 100
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
BIOTREND GmbH
Tel
--
Fax
--
Email
jaeger@biotrend.com
Country
Germany
ProdList
249
Advantage
65
BIOTREND Chemicals AG
Tel
--
Fax
--
Email
info@biotrend.ch
Country
Germany
ProdList
1250
Advantage
62
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View Lastest Price from TFLLR-NH2 manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
TFLLR-NH2 197794-83-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10
Career Henan Chemical Co
Product
TFLLR-NH2 197794-83-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-13

197794-83-5, TFLLR-NH2Related Search:

DL-Threonine hydrate(2:1) ANTI HUMAN TR-ALPHA Trifluoroacetamide H-SER-PHE-LEU-LEU-ARG-NH2 TFLLR-NH2 H-THR-PHE-LEU-LEU-ARG-NH2 TRIFLUOROACETATE SALT THR-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-NH2

  • H-THR-PHE-LEU-LEU-ARG-NH2
  • THR-PHE-LEU-LEU-ARG-NH2
  • THROMBIN RECEPTOR (PAR-1), HYBRIDE HUMAN-XENOPE
  • TFLLR-AMIDE
  • TFLLR-NH2
  • (Thr1)-TRAP-5 amide
  • TFLLR-NH2 Protease-Activated Receptor 1 (PAR1) Agonist
  • (2S)-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
  • TFLLR-NH2(2TFA)
  • TFLLRaMide, (Thr1)-TRAP-5 aMide, (Thr1)-PAR-1 (1-5) aMide (huMan)
  • HYBRIDE HUMAN-XENOPE
  • TFLLR
  • REF DUPL: H-Thr-Phe-Leu-Leu-Arg-NH2
  • (Thr1)-PAR-1 (1-5) amide (human)
  • L-Argininamide, L-threonyl-L-phenylalanyl-L-leucyl-L-leucyl-
  • TFLLR-NH2 2TFA(197794-83-5(free base))
  • TFLLR NH2 2TFA(197794 83 5(free base)),TFLLR-NH-2 2TFA(197794-83-5(free base)),TFLLRNH2 2TFA(197794835(free base))
  • 1313730-19-6/197794-83-5
  • (Thr?)-PAR-1 (1-5) amide (human) trifluoroacetate salt
  • TFLLR-NH2, PAR1 agonist peptide
  • PAR-1 agonist/ TRAP6
  • 197794-83-5
  • C31H53N9O6
  • C35H55F6N9O10
  • Proteinase-activated receptor (PAR)
  • Peptide Receptors