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p-Acetylamino benzoic acid

Product Name
p-Acetylamino benzoic acid
CAS No.
556-08-1
Chemical Name
p-Acetylamino benzoic acid
Synonyms
P-ACETAMIDOBENZOIC ACID;4-ACETAMIDOBENZOIC ACID;Acedoben;p-acetamidobenzoic;PAAB;P-ACETAMINOBENZOIC ACID;4-ACETAMIDOBENZOIC ACID FOR SYNTHESIS;p-Acetylamino benzoic acido benzoic acid;LR-64;PAABA
CBNumber
CB9465840
Molecular Formula
C9H9NO3
Formula Weight
179.17
MOL File
556-08-1.mol
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p-Acetylamino benzoic acid Property

Melting point:
259-262 °C (dec.)(lit.)
Boiling point:
311.69°C (rough estimate)
Density 
1.2822 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder
pka
pK1: 4.28 (25°C)
color 
Off-white to slightly beige
Water Solubility 
<0.1 g/100 mL at 21 ºC
BRN 
390602
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference
556-08-1(CAS DataBase Reference)
NIST Chemistry Reference
N-(4-Carboxyphenyl)acetic acid amide(556-08-1)
EPA Substance Registry System
Benzoic acid, 4-(acetylamino)- (556-08-1)
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Safety

Risk Statements 
36/37/38
Safety Statements 
24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29242995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
133337
Product name
4-Acetamidobenzoic acid
Purity
98%
Packaging
25g
Price
$39.5
Updated
2024/03/01
TCI Chemical
Product number
A0013
Product name
4-Acetamidobenzoic Acid
Purity
>99.0%(T)
Packaging
25g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
A0013
Product name
4-Acetamidobenzoic Acid
Purity
>99.0%(T)
Packaging
500g
Price
$173
Updated
2024/03/01
Alfa Aesar
Product number
A12711
Product name
4-Acetamidobenzoic acid, 98%
Packaging
50g
Price
$40.65
Updated
2024/03/01
Alfa Aesar
Product number
A12711
Product name
4-Acetamidobenzoic acid, 98%
Packaging
250g
Price
$161.65
Updated
2024/03/01
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p-Acetylamino benzoic acid Chemical Properties,Usage,Production

Chemical Properties

white or off-white powder or crystals

Originator

4-Acetamidobenzoic acid ,ARIAC

Uses

immune stimulant (component)

Uses

Acedoben is the acetylated derivative of p-aminobenzoic acid (PABA). Acedoben is a metabolite of the anesthetic Benzocaine (B202970).

Definition

ChEBI: A amidobenzoic acid that consists of benzoic acid bearing an acetamido substituent at position 4.

Manufacturing Process

Into a 2 L, 3-necked flask set in a tub and equipped with a stirrer, an air condenser (drying tube), thermometer, was placed 860 ml of water, 43.0 g of MgSO4 and 43.0 g of sodium acetate and heated on water bath. Into heated solution to 70°C stirring 43.0 g of N-p-tolylacetamide were added. Then 136.0 g of KMnO4 by small portions were added at 75°-80°C. The reaction mixture allow to stand for 6 h and stirring was continue till the solution became colorless. Hot solution was filtered and filtrate treated hydrochloric acid to slightly acidic pH. After that 44.0 g (85%) of p-acetoaminobenzoic acid was obtained as white precipitate, melting point 250°C.

Therapeutic Function

Antiviral

General Description

Needles or off-white powder.

Air & Water Reactions

Water insoluble.

Reactivity Profile

Simultaneously an amide and a carboxylic acid.

Fire Hazard

Flash point data for p-Acetylamino benzoic acid are not available; however, p-Acetylamino benzoic acid is probably combustible.

p-Acetylamino benzoic acid Preparation Products And Raw materials

Raw materials

4-Aminobenzoic acid

Preparation Products

4-Acetamido-3-nitrobenzoic acid
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p-Acetylamino benzoic acid Suppliers

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View Lastest Price from p-Acetylamino benzoic acid manufacturers

Shenyang Simchoice Chemical Co.,Ltd
Product
P-Acetamidobenzoic acid 556-08-1
Price
US $20.50-20.30/KG
Min. Order
500KG
Purity
99.55 USP
Supply Ability
200tons per month
Release date
2019-12-04
Hebei Yanxi Chemical Co., Ltd.
Product
p-Acetylamino benzoic acid 556-08-1
Price
US $10.00-3.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-28
Hebei Guanlang Biotechnology Co., Ltd.
Product
p-Acetylamino benzoic acid 556-08-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-08

556-08-1, p-Acetylamino benzoic acidRelated Search:

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  • 4-(acetylamino)-benzoicaci
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  • Acedoben (4-(AcetylaMino)benzoic acid)
  • 4-AcetaMidobenzoic acid 98%
  • RARECHEM AL BO 0055
  • N-(4-Carboxyphenyl)acetic acid amide
  • N-ACETYL-4-CARBOXYANILINE
  • N-ACETYL-1-AMINO-4-CARBOXYBENZENE
  • N-ACETYL-PABA
  • n-acetyl-p-aminobenzoic acid
  • P-ACETAMINOPHENYLCARBOXYLIC ACID
  • P-ACETYLAMINOPHENYLCARBOXYLIC ACID
  • P-ACETYLAMIDOBENZOIC ACID
  • P-ACETYLAMINO BENZOIC ACID
  • P-ACETAMINOBENZOIC ACID
  • P-ACETAMIDOBENZOIC ACID
  • P-ACETAMIDOPHENYLCARBOXYLIC ACID
  • PAABA
  • 4-Acetamidobenzoic Acid &gt
  • p-Acetylamino benzoic acido benzoic acid
  • P-ACETYLAMINO BENZOIC ACID CAS 556-08-1
  • p-Acetylamino benzoic acid 556-08-1
  • Acetaminobenzoic
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  • Acedoben (4-Acetamidobenzoic acid)
  • Phosphoric acid 7664-38-2
  • 556-08-1
  • 556-09-1
  • CH3CONHC6H4CO2H
  • Unnatural Amino Acid Derivatives
  • Specialty Synthesis
  • Peptide Synthesis
  • Aromatic Amino Acids
  • IMUNOVIR