Meclofenoxate hydrochloride

Pharmacological action Uses

Product Name: Meclofenoxate hydrochloride
CAS No.: 3685-84-5
Chemical Name: Meclofenoxate hydrochloride
Synonyms: CENTROPHENOXINE;MECLOFENOXATE HCL;CENTROPHENOXIN;mko;Cerut;acefen;brenal;cerutil;amipolen;cellative
CBNumber: CB9471047
Molecular Formula: C12H16ClNO3.ClH
Formula Weight: 294.17
MOL File: 3685-84-5.mol

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Meclofenoxate hydrochloride Property

Melting point:: 133-135°C
Density: 1.3255 (rough estimate)
refractive index: 1.6140 (estimate)
storage temp.: −20°C
solubility: DMSO (Sparingly), Methanol (Slightly)
form: Solid
color: White to Off-White
Merck: 14,5780
InChI: InChI=1S/C12H16ClNO3.ClH/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11;/h3-6H,7-9H2,1-2H3;1H
InChIKey: FIVHOHCAXWQPGC-UHFFFAOYSA-N
SMILES: C(OCCN(C)C)(=O)COC1=CC=C(Cl)C=C1.[H]Cl
CAS DataBase Reference: 3685-84-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36
RTECS: AG0440000
Toxicity: LD50 in mice (mg/kg): 330 i.v.; 1750 orally; 845 i.p. (Rumpf, Thuillier)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

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N-Bromosuccinimide Price

Alfa Aesar

Product number: J64196
Product name: Centrophenoxine hydrochloride, 98%
Packaging: 5g
Price: $40.65
Updated: 2024/03/01

Alfa Aesar

Product number: J64196
Product name: Centrophenoxine hydrochloride, 98%
Packaging: 25g
Price: $88.65
Updated: 2024/03/01

Cayman Chemical

Product number: 28283
Product name: Meclofenoxate (hydrochloride)
Packaging: 25g
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 28283
Product name: Meclofenoxate (hydrochloride)
Packaging: 50g
Price: $139
Updated: 2024/03/01

Alfa Aesar

Product number: J64196
Product name: Centrophenoxine hydrochloride, 98%
Packaging: 100g
Price: $299.65
Updated: 2024/03/01

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Meclofenoxate hydrochloride Chemical Properties,Usage,Production

Pharmacological action

Meclofenoxate hydrochloride(MecloCl) [CAS,NO:51-68-3], an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition.
Meclofenoxate hydrochloride is a psychostimulant in the nootropic agent group available in capsule and tablet formulations approved for traumatic cataphora, alcoholic poisoning, anoxia neonatorum, and children's enuresis in China. Although these 2 generic formulations are marketed in China, information regarding their pharmacokinetics and bioequivalence in humans has not been published. Meclofenoxate hydrochloride appears to increase the consolidation of new information into long-term memory. Meclofenoxate does not affect other aspects of remembering. Meclofenoxate is found that significantly more of the subjects receiving meclofenoxate reportes an increased level of mental alertness.

Uses

The applications of is Meclofenoxate hydrochloride:

Memory decline through aging
Dementia and Alzheimer’s (clinically)
Brain damage or injuries
Alcohol or drug abuse symptoms and effects
Promote the metabolism of brain

Description

Meclofenoxate hydrochloride is a cholinergic nootropic used as a dietary supplement and drug in the treatment of symptoms of senile dementia and Alzheimer's disease.

Chemical Properties

White Solid

Uses

Meclofenoxate is a cerebral stimulant. Also, Meclofenoxate is used as plant growth regulator.

Uses

Cerebral stimulant;Acetylcholine precursor

Mechanism of action

Meclofenoxate hydrochloride is a cholinergic drug that has been used to treat bowel diseases. It inhibits the enzyme acetylcholinesterase, which breaks down acetylcholine in the body and thus increases the amount of acetylcholine available to stimulate muscle contractions. Meclofenoxate hydrochloride also affects the production of other enzymes, such as those involved in energy metabolism.

Side effects

Possible side effects of meclofenoxate include insomnia, dizziness, restlessness, muscle tremors, depression, nausea, muscle tension, and headache, which are generally rare; these side effects may be associated with overdose of the medication and may indicate the need for a reduction in the dosage of the medication.

Safety Profile

Poison by intravenous route.Moderately toxic by ingestion and intraperitoneal routes.When heated to decomposition it emits very toxic fumes ofCl??, NOx, and HCl.

Meclofenoxate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Meclofenoxate hydrochloride Suppliers

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View Lastest Price from Meclofenoxate hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Meclofenoxate hydrochloride 3685-84-5
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98.5%min
Supply Ability: 1000KG
Release date: 2021-06-08

Wuhan Nutra Biotechnology Co.,Ltd

Product: Meclofenoxate Hydrochloride;Centrophenoxine 3685-84-5
Price: US $0.00-0.00/g
Min. Order: 100g
Purity: 98%
Supply Ability: 1000kgs
Release date: 2021-05-26

Hebei Chuanghai Biotechnology Co,.LTD

Product: Meclofenoxate hydrochloride 3685-84-5
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-15

3685-84-5, Meclofenoxate hydrochloride Related Search:

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3685-84-5

685-84-5

C12H17Cl2NO3

C12H16ClNO3HClC12H17Cl2NO3

C12H16ClNO3HCl

C12H16ClNO3xHCl

C12H16ClNO3ClH