Applications Immunogen Background

PIN1 ANTIBODY

Applications Immunogen Background
Product Name
PIN1 ANTIBODY
Chemical Name
PIN1 ANTIBODY
Synonyms
PIN1 ANTIBODY
CBNumber
CB94731693
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb99449
Product name
Pin1 antibody
Purity
Immunogen affinity purified
Packaging
20μl(Trial size)
Price
$256.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb162394
Product name
Pin1 antibody
Purity
Affinity-purified by affinity-chromatography using epitope-specific immunogen.
Packaging
100μg
Price
$280.5
Updated
2021/12/16
Biorbyt Ltd
Product number
orb48491
Product name
PIN1 antibody
Purity
Affinity purification
Packaging
50μl
Price
$316.2
Updated
2021/12/16
Biorbyt Ltd
Product number
orb99449
Product name
Pin1 antibody
Purity
Immunogen affinity purified
Packaging
50μl
Price
$357
Updated
2021/12/16
Biorbyt Ltd
Product number
orb48491
Product name
PIN1 antibody
Purity
Affinity purification
Packaging
100μL
Price
$384.2
Updated
2021/12/16
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PIN1 ANTIBODY Chemical Properties,Usage,Production

Applications

PIN1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.

Immunogen

Anti-human PIN1 mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PIN1 amino acids 1-163 purified from E. coli.

Background

Human Pin 1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA, PLK I, Wee, and Myt1 kinases), several transcription factors like β-Catenin, c-Jun, and the tumor suppressor protein p53, and some specific proteins like the RNA Pol II, the cytoskeleton protein tau, and the G1/S protein Cyclin D1.

PIN1 ANTIBODY Preparation Products And Raw materials

Raw materials

Preparation Products

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PIN1 ANTIBODY Suppliers

CHINA 67 Japan 1 Global 68
Absin Bioscience Inc.
Tel
021-38015121 18438616290
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  • PIN1 ANTIBODY