PIN1 ANTIBODY
Applications Immunogen Background- Product Name
- PIN1 ANTIBODY
- Chemical Name
- PIN1 ANTIBODY
- Synonyms
- PIN1 ANTIBODY
- CBNumber
- CB94731693
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb99449
- Product name
- Pin1 antibody
- Purity
- Immunogen affinity purified
- Packaging
- 20μl(Trial size)
- Price
- $256.7
- Updated
- 2021/12/16
- Product number
- orb162394
- Product name
- Pin1 antibody
- Purity
- Affinity-purified by affinity-chromatography using epitope-specific immunogen.
- Packaging
- 100μg
- Price
- $280.5
- Updated
- 2021/12/16
- Product number
- orb48491
- Product name
- PIN1 antibody
- Purity
- Affinity purification
- Packaging
- 50μl
- Price
- $316.2
- Updated
- 2021/12/16
- Product number
- orb99449
- Product name
- Pin1 antibody
- Purity
- Immunogen affinity purified
- Packaging
- 50μl
- Price
- $357
- Updated
- 2021/12/16
- Product number
- orb48491
- Product name
- PIN1 antibody
- Purity
- Affinity purification
- Packaging
- 100μL
- Price
- $384.2
- Updated
- 2021/12/16
PIN1 ANTIBODY Chemical Properties,Usage,Production
Applications
PIN1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.
Immunogen
Anti-human PIN1 mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PIN1 amino acids 1-163 purified from E. coli.
Background
Human Pin 1 is a peptidyl-prolyl cis/trans isomerase (PPIase) that interacts with NIMA and essential for cell cycle regulation Pin1 is nuclear PPIase containing a WW protein interaction domain, and is structurally and functionally related to Ess1/Ptf1, an essential protein in budding yeast. PPIase activity is necessary for Ess1/Pin1 function in yeast. Pin1 is thus an essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Substrates of Pin1 include the mitotic regulators (Cdc25 phosphatase and NIMA, PLK I, Wee, and Myt1 kinases), several transcription factors like β-Catenin, c-Jun, and the tumor suppressor protein p53, and some specific proteins like the RNA Pol II, the cytoskeleton protein tau, and the G1/S protein Cyclin D1.
PIN1 ANTIBODY Preparation Products And Raw materials
Raw materials
Preparation Products
PIN1 ANTIBODY Suppliers
- Tel
- --
- Fax
- --
- reag-info@gms.kanto.co.jp
- Country
- Japan
- ProdList
- 6756
- Advantage
- 74