2-AMINO CYCLOPENTANOL
Uses- Product Name
- 2-AMINO CYCLOPENTANOL
- CAS No.
- 89381-13-5
- Chemical Name
- 2-AMINO CYCLOPENTANOL
- Synonyms
- 2-aminocyclopentan-1-ol;2-AminocycL;2-AMINO CYCLOPENTANOL;Cyclopentanol, 2-aMino-;2-HydroxycyclopentylaMine;2-AMinocyclopentanol, 95+%;trans-2-Amino-cyclopentanol;1-AMino-2-hydroxycyclopentane;Cyclopentanol,2-amino-(6CI,7CI,9CI)
- CBNumber
- CB9476628
- Molecular Formula
- C5H11NO
- Formula Weight
- 101.15
- MOL File
- 89381-13-5.mol
2-AMINO CYCLOPENTANOL Property
- Boiling point:
- 114-115℃ (13 Torr)
- Density
- 1.0617 g/cm3(Temp: 15 °C)
- refractive index
- 1.4965 (589.3 nm 15℃)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 14.93±0.40(Predicted)
- Appearance
- Colorless to light yellow Liquid
- CAS DataBase Reference
- 89381-13-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-39
- RIDADR
- UN3082
- HazardClass
- 9
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P330Rinse mouth.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A596510
- Product name
- 2-Aminocyclopentanol
- Packaging
- 100mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- A596510
- Product name
- 2-Aminocyclopentanol
- Packaging
- 500mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- FA140922
- Product name
- 2-Aminocyclopentanol
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FA140922
- Product name
- 2-Aminocyclopentanol
- Packaging
- 500mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- FA140922
- Product name
- 2-Aminocyclopentanol
- Packaging
- 1g
- Price
- $243.75
- Updated
- 2021/12/16
2-AMINO CYCLOPENTANOL Chemical Properties,Usage,Production
Uses
2-Aminocyclopentanol can be used as a pharmaceutical synthesis intermediate. It can be prepared from cyclopentane oxide as a reaction raw material. It can be used to prepare 5-methyl-2-(pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one compounds. It can also be used to prepare drugs for treating diseases related to cyclin-dependent kinase signaling pathways.
Synthesis
672310-36-0
930-45-0
General procedure for the synthesis of (1S,2S)-2-aminocyclopentanol from the compound (CAS:672310-36-0): 0.900 g (3.82 mmol) of (S,S)-2-benzyloxycarbonylaminocyclopentanol and 0.36 g of 5% palladium-carbon catalyst were added to the reaction system in a 50 mL autoclave. Under nitrogen protection, 4.5 mL of degassed methanol was added to the reaction system. The reaction mixture was stirred at 50 °C for 3 hours under hydrogen pressure of 2 MPa. Upon completion of the reaction, the palladium-carbon catalyst was removed by diatomaceous earth filtration, and the filtrate was concentrated by rotary evaporator to give 0.59 g of crude product. The product was determined to have an enantiomeric excess (ee) percentage of more than 99%. The 1H-NMR (200 MHz, CDCl3) data of the product were as follows: δ 1.2-1.3 (m, 1H), 1.5 (m, 1H), 1.6-1.7 (m, 2H), 1.9-2.0 (m, 2H), 2.3-2.5 (br, 3H), 3.0 (m, 1H), 3.7 (m, 1H).
References
[1] Patent: EP1398310, 2004, A1. Location in patent: Page 16-17
2-AMINO CYCLOPENTANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO CYCLOPENTANOL manufacturers
- Product
- 2-AMINO CYCLOPENTANOL 89381-13-5
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100g , 1kg, 5kg , 50kg
- Release date
- 2020-01-07