ChemicalBook > CAS DataBase List > SB 205384

SB 205384

Product Name
SB 205384
CAS No.
160296-13-9
Chemical Name
SB 205384
Synonyms
SB 205384;SB 205384 solid;4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-(1H)benzothieno[2,3-b]pyridine-3-carboxylicacid2-butynylester;4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester;4-AMINO-5,6,7,8-TETRAHYDRO-7-HYDROXY-2-METHYL-[1H]BENZOTHIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID 2-BUTYNYL ESTER;[1]Benzothieno[2,3-b]pyridine-3-carboxylic acid, 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-, 2-butyn-1-yl ester
CBNumber
CB9476860
Molecular Formula
C17H18N2O3S
Formula Weight
330.4
MOL File
160296-13-9.mol
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SB 205384 Property

Boiling point:
565.3±50.0 °C(Predicted)
Density 
1.380±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at RT
solubility 
DMSO: 18 mg/mL
form 
solid
pka
14.28±0.20(Predicted)
color 
off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S7936
Product name
SB 205384
Purity
solid
Packaging
5mg
Price
$261
Updated
2025/07/31
Sigma-Aldrich
Product number
S7936
Product name
SB 205384
Purity
solid
Packaging
25mg
Price
$853
Updated
2022/05/15
Tocris
Product number
1512
Product name
SB 205384
Purity
≥98%(HPLC)
Packaging
50
Price
$523
Updated
2021/12/16
Tocris
Product number
1512
Product name
SB 205384
Purity
≥98%(HPLC)
Packaging
10
Price
$141
Updated
2021/12/16
Usbiological
Product number
256611
Product name
SB 205384
Packaging
10mg
Price
$466
Updated
2021/12/16
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SB 205384 Chemical Properties,Usage,Production

Uses

SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity.

Definition

ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine.

Biological Activity

GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits.

SB 205384 Preparation Products And Raw materials

Raw materials

Preparation Products

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SB 205384 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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160296-13-9, SB 205384Related Search:


  • SB 205384
  • 4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-(1H)benzothieno[2,3-b]pyridine-3-carboxylicacid2-butynylester
  • 4-AMINO-5,6,7,8-TETRAHYDRO-7-HYDROXY-2-METHYL-[1H]BENZOTHIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID 2-BUTYNYL ESTER
  • [1]Benzothieno[2,3-b]pyridine-3-carboxylic acid, 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-, 2-butyn-1-yl ester
  • SB 205384 solid
  • 4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester
  • 160296-13-9
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Ligand-Gated Ion Channels
  • Ion Channels
  • GABA and Glycine Receptor Modulators
  • GABA/Glycine receptor