SB 205384

Product Name: SB 205384
CAS No.: 160296-13-9
Chemical Name: SB 205384
Synonyms: SB 205384;SB 205384 solid;4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-(1H)benzothieno[2,3-b]pyridine-3-carboxylicacid2-butynylester;4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester;4-AMINO-7-HYDROXY-2-METHYL-5,6,7,8-TETRAHYDROBENZO[B]THIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID BUT-2-YNYL ESTER;4-AMINO-5,6,7,8-TETRAHYDRO-7-HYDROXY-2-METHYL-[1H]BENZOTHIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID 2-BUTYNYL ESTER;[1]Benzothieno[2,3-b]pyridine-3-carboxylic acid, 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-, 2-butyn-1-yl ester
CBNumber: CB9476860
Molecular Formula: C17H18N2O3S
Formula Weight: 330.4
MOL File: 160296-13-9.mol

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SB 205384 Property

Boiling point:: 565.3±50.0 °C(Predicted)
Density: 1.380±0.06 g/cm3(Predicted)
storage temp.: Desiccate at RT
solubility: DMSO: 18 mg/mL
form: solid
pka: 14.28±0.20(Predicted)
color: off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S7936
Product name: SB 205384
Purity: solid
Packaging: 5mg
Price: $254
Updated: 2024/03/01

Sigma-Aldrich

Product number: S7936
Product name: SB 205384
Purity: solid
Packaging: 25mg
Price: $853
Updated: 2022/05/15

Tocris

Product number: 1512
Product name: SB 205384
Purity: ≥98%(HPLC)
Packaging: 50
Price: $523
Updated: 2021/12/16

Tocris

Product number: 1512
Product name: SB 205384
Purity: ≥98%(HPLC)
Packaging: 10
Price: $141
Updated: 2021/12/16

Usbiological

Product number: 256611
Product name: SB 205384
Packaging: 10mg
Price: $466
Updated: 2021/12/16

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SB 205384 Chemical Properties,Usage,Production

Uses

SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity.

Definition

ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine.

Biological Activity

GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits.

SB 205384 Preparation Products And Raw materials

Raw materials

Preparation Products

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SB 205384 Suppliers

China 21 Germany 2 Switzerland 1 United Kingdom 1 United States 4 Global 29

160296-13-9, SB 205384Related Search:

4-AMINOPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 1-THIOPHEN-2-YL-PROPAN-2-OL SB 205384 PROP-2-YNYL NICOTINATE THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER 4-Amino-3-pyridinecarboxylic acid Methyl 4-aminopyridine-3-carboxylate (4-AMINO-PYRIDIN-3-YL)-METHANOL 4-AMINO-3-FORMYLPYRIDINE 2-BUTYNYL ACETATE

SB 205384

4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-(1H)benzothieno[2,3-b]pyridine-3-carboxylicacid2-butynylester

4-AMINO-5,6,7,8-TETRAHYDRO-7-HYDROXY-2-METHYL-[1H]BENZOTHIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID 2-BUTYNYL ESTER

4-AMINO-7-HYDROXY-2-METHYL-5,6,7,8-TETRAHYDROBENZO[B]THIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID BUT-2-YNYL ESTER

[1]Benzothieno[2,3-b]pyridine-3-carboxylic acid, 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-, 2-butyn-1-yl ester

SB 205384 solid

4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester

160296-13-9

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Ligand-Gated Ion Channels

Ion Channels

GABA and Glycine Receptor Modulators

GABA/Glycine receptor