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1-(6-Chloro-pyridazino-3-yl)piperidine

Product Name
1-(6-Chloro-pyridazino-3-yl)piperidine
CAS No.
1722-11-8
Chemical Name
1-(6-Chloro-pyridazino-3-yl)piperidine
Synonyms
3-Chloro-6-piperidinopyridazine;3-chloro-6-(1-piperidyl)pyridazine;3-CHLORO-6-(1-PIPERIDINYL)PYRIDAZINE;3-CHLORO-6-PIPERIDIN-1-YL-PYRIDAZINE;1-(6-CHLORO-PYRIDAZINO-3-YL)PIPERIDINE;Pyridazine, 3-chloro-6-(1-piperidinyl)-;1-(6-Chloro-pyridazino-3-yl)piperidine ISO 9001:2015 REACH;3-CHLORO-6-(1-PIPERIDINYL)PYRIDAZINE
CBNumber
CB9476936
Molecular Formula
C9H12ClN3
Formula Weight
197.66
MOL File
1722-11-8.mol
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1-(6-Chloro-pyridazino-3-yl)piperidine Property

Melting point:
80~82℃
Boiling point:
388.6±27.0 °C(Predicted)
Density 
1.234±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
3.62±0.10(Predicted)
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C350910
Product name
3-Chloro-6-(piperidin-1-yl)pyridazine
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
C350910
Product name
3-Chloro-6-(piperidin-1-yl)pyridazine
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
C350910
Product name
3-Chloro-6-(piperidin-1-yl)pyridazine
Packaging
1g
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC53919
Product name
3-Chloro-6-(1-piperidinyl)pyridazine
Packaging
1g
Price
$79.1
Updated
2021/12/16
Apolloscientific
Product number
OR959487
Product name
3-Chloro-6-(piperidin-1-yl)pyridazine
Purity
98%
Packaging
1g
Price
$85
Updated
2021/12/16
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1-(6-Chloro-pyridazino-3-yl)piperidine Chemical Properties,Usage,Production

Synthesis

110-89-4

141-30-0

1722-11-8

GENERAL METHOD: Anhydrous ethanol (5 mL) and 3,6-dichloropyridazine (3.36 mmol) were added to a 50 mL round-bottomed flask, followed by triethylamine (5.03 mmol) and hexahydropyridine (5.03 mmol). The reaction mixture was stirred under ethanol reflux conditions for 3,6-dichloropyridazine and 3,6-dichloropyrazine and at room temperature for 3,6-dichloropyrimidine. The reaction process was monitored by gas chromatography (GC). When the starting material 3,6-dichloropyridazine was completely consumed, the reaction mixture was poured into saturated ammonium chloride solution (20 mL) and extracted with dichloromethane (3 x 20 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was ground with petroleum ether and filtered through a Büchner funnel to give pure 1-(6-chloropyridazin-3-yl)piperidine.

References

[1] Tetrahedron, 2015, vol. 71, # 29, p. 4859 - 4867
[2] Journal of Organic Chemistry, 2013, vol. 78, # 2, p. 370 - 379
[3] European Journal of Medicinal Chemistry, 2015, vol. 95, p. 277 - 301
[4] Yakugaku Zasshi, 1954, vol. 74, p. 1195,1197
[5] Chem.Abstr., 1955, p. 14768

1-(6-Chloro-pyridazino-3-yl)piperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(6-Chloro-pyridazino-3-yl)piperidine Suppliers

AsInEx Ltd.
Tel
--
Fax
--
Email
asinex@asinex.com
Country
Russia
ProdList
6615
Advantage
66
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View Lastest Price from 1-(6-Chloro-pyridazino-3-yl)piperidine manufacturers

Dideu Industries Group Limited
Product
1-(6-Chloro-pyridazino-3-yl)piperidine 1722-11-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-11-08
Career Henan Chemical Co
Product
1-(6-Chloro-pyridazino-3-yl)piperidine 1722-11-8
Price
US $5.00/KG
Min. Order
5KG
Purity
99%
Supply Ability
1ton
Release date
2019-08-02