ANTIMYCIN A1
- Product Name
- ANTIMYCIN A1
- CAS No.
- 642-15-9
- Chemical Name
- ANTIMYCIN A1
- Synonyms
- ANTIMYCIN A1;dihydrosamidin;1,5-Dioxonane butanoic acid deriv.;-dioxo-1,5-dioxonan-3-yl)salicylamide;isovalericacid,8-esterwith3-formamido-n-(7-hexyl-8-hydroxy-4,9-dimethyl-2,6;3-(3-formamidosalicylamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl isovalerate;[3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate;[3-[(3-formamido-2-hydroxy-phenyl)carbonylamino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate;3-methylbutyric acid [3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-4,9-diketo-2,6-dimethyl-1,5-dioxonan-7-yl] ester;3-Methylbutyric acid 3-[[3-(formylamino)-2-hydroxybenzoyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
- CBNumber
- CB9479432
- Molecular Formula
- C28H40N2O9
- Formula Weight
- 548.63
- MOL File
- 642-15-9.mol
ANTIMYCIN A1 Property
- Melting point:
- 149.5℃
- alpha
- D26 +76° (c = 1 in chloroform)
- Boiling point:
- 620.81°C (rough estimate)
- Density
- 1.2468 (rough estimate)
- refractive index
- 1.5800 (estimate)
- storage temp.
- −20°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A solid
Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25
- Safety Statements
- 36/37/39-45
- RIDADR
- 3172
- RTECS
- NY1503500
- HazardClass
- 6.1(a)
- PackingGroup
- II
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H311Toxic in contact with skin
H331Toxic if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P311Call a POISON CENTER or doctor/physician.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P361Remove/Take off immediately all contaminated clothing.
P363Wash contaminated clothing before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 19433
- Product name
- Antimycin A1
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $183
- Updated
- 2024/03/01
- Product number
- 19433
- Product name
- Antimycin A1
- Purity
- ≥98%
- Packaging
- 2.5mg
- Price
- $777
- Updated
- 2024/03/01
- Product number
- CS-0028420
- Product name
- AntimycinA1
- Purity
- ≥98.0%
- Packaging
- 500ug
- Price
- $340
- Updated
- 2021/12/16
- Product number
- API0010174
- Product name
- ANTIMYCIN A1
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.35
- Updated
- 2021/12/16
- Product number
- CS-0028420
- Product name
- AntimycinA1
- Purity
- ≥98.0%
- Packaging
- 1mg
- Price
- $550
- Updated
- 2021/12/16
ANTIMYCIN A1 Chemical Properties,Usage,Production
Description
Antimycin A1 is an active component of the antimycin A antibiotic complex. It inhibits electron transport and is active against the plant pathogenic fungus G. cingulate. Antimycin A1 (3.3-160 μM) induces the synthesis of carotenoids in M. marinum. It also inhibits ATP-citrate lyase (Ki = 29.5 μM).
Chemical Properties
Antimycin (A3C26H36N2O9) and (Antimycin A1) C28H40N2O9 are crystalline solids.
Chemical Properties
Crystals. Soluble in alcohol, ether, acetone, and chloroform; slightly soluble in benzene, carbon tetrachloride, and petroleum ether; insoluble in water.
Uses
Antimycin A1 is the most hydrophobic of the four analogues of the antimycin A complex. Like all antimycins, antimycin A1 exhibits potent antifungal, anthelmintic, insecticidal, antiviral and antitumor activity across a range of bioassays. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of individual members of the complex as bioprobes. Antimycin A1 inhibits angiogenesis via a decrease in VEGF production caused by inhibition of HIF-1a activation.
Uses
Experimentally as fungicide, insecticide, miticide.
Definition
An antibiotic substance said to have strong fungicidal properties.
Potential Exposure
Specific uses for antimycin A were not found, however, antimycin A1, and antimycin A3 are reported to be antibiotic substances produced by streptomyces for use as a fungicide, possible insecticide and miticide. Registered as a pesticide in the U.S.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
ANTIMYCIN A1 Preparation Products And Raw materials
Raw materials
Preparation Products
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