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ANTIMYCIN A1

Product Name
ANTIMYCIN A1
CAS No.
642-15-9
Chemical Name
ANTIMYCIN A1
Synonyms
ANTIMYCIN A1;dihydrosamidin;1,5-Dioxonane butanoic acid deriv.;-dioxo-1,5-dioxonan-3-yl)salicylamide;isovalericacid,8-esterwith3-formamido-n-(7-hexyl-8-hydroxy-4,9-dimethyl-2,6;3-(3-formamidosalicylamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl isovalerate;[3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate;[3-[(3-formamido-2-hydroxy-phenyl)carbonylamino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate;3-methylbutyric acid [3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-4,9-diketo-2,6-dimethyl-1,5-dioxonan-7-yl] ester;3-Methylbutyric acid 3-[[3-(formylamino)-2-hydroxybenzoyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
CBNumber
CB9479432
Molecular Formula
C28H40N2O9
Formula Weight
548.63
MOL File
642-15-9.mol
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ANTIMYCIN A1 Property

Melting point:
149.5℃
alpha 
D26 +76° (c = 1 in chloroform)
Boiling point:
620.81°C (rough estimate)
Density 
1.2468 (rough estimate)
refractive index 
1.5800 (estimate)
storage temp. 
−20°C
solubility 
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
36/37/39-45
RIDADR 
3172
RTECS 
NY1503500
HazardClass 
6.1(a)
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19433
Product name
Antimycin A1
Purity
≥98%
Packaging
500μg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
19433
Product name
Antimycin A1
Purity
≥98%
Packaging
2.5mg
Price
$777
Updated
2024/03/01
ChemScene
Product number
CS-0028420
Product name
AntimycinA1
Purity
≥98.0%
Packaging
500ug
Price
$340
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010174
Product name
ANTIMYCIN A1
Purity
95.00%
Packaging
5MG
Price
$499.35
Updated
2021/12/16
ChemScene
Product number
CS-0028420
Product name
AntimycinA1
Purity
≥98.0%
Packaging
1mg
Price
$550
Updated
2021/12/16
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ANTIMYCIN A1 Chemical Properties,Usage,Production

Description

Antimycin A1 is an active component of the antimycin A antibiotic complex. It inhibits electron transport and is active against the plant pathogenic fungus G. cingulate. Antimycin A1 (3.3-160 μM) induces the synthesis of carotenoids in M. marinum. It also inhibits ATP-citrate lyase (Ki = 29.5 μM).

Chemical Properties

Antimycin (A3C26H36N2O9) and (Antimycin A1) C28H40N2O9 are crystalline solids.

Chemical Properties

Crystals. Soluble in alcohol, ether, acetone, and chloroform; slightly soluble in benzene, carbon tetrachloride, and petroleum ether; insoluble in water.

Uses

Antimycin A1 is the most hydrophobic of the four analogues of the antimycin A complex. Like all antimycins, antimycin A1 exhibits potent antifungal, anthelmintic, insecticidal, antiviral and antitumor activity across a range of bioassays. Although broadly active as respiration inhibitors, more recent investigation has highlighted the importance of individual members of the complex as bioprobes. Antimycin A1 inhibits angiogenesis via a decrease in VEGF production caused by inhibition of HIF-1a activation.

Uses

Experimentally as fungicide, insecticide, miticide.

Definition

An antibiotic substance said to have strong fungicidal properties.

Potential Exposure

Specific uses for antimycin A were not found, however, antimycin A1, and antimycin A3 are reported to be antibiotic substances produced by streptomyces for use as a fungicide, possible insecticide and miticide. Registered as a pesticide in the U.S.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

ANTIMYCIN A1 Preparation Products And Raw materials

Raw materials

Preparation Products

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ANTIMYCIN A1 Suppliers

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642-15-9, ANTIMYCIN A1Related Search:


  • dihydrosamidin
  • -dioxo-1,5-dioxonan-3-yl)salicylamide
  • isovalericacid,8-esterwith3-formamido-n-(7-hexyl-8-hydroxy-4,9-dimethyl-2,6
  • ANTIMYCIN A1
  • 3-(3-formamidosalicylamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl isovalerate
  • 3-Methylbutanoic acid 3-[[3-(formylamino)-2-hydroxybenzoyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
  • 3-Methylbutyric acid 3-[[3-(formylamino)-2-hydroxybenzoyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
  • [3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate
  • [3-[(3-formamido-2-hydroxy-phenyl)carbonylamino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate
  • 3-methylbutyric acid [3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-4,9-diketo-2,6-dimethyl-1,5-dioxonan-7-yl] ester
  • 1,5-Dioxonane butanoic acid deriv.
  • 642-15-9
  • C16H21NO2
  • C28H40N2O9