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Dolutegravir 4-Desfluoro Impurity

Product Name
Dolutegravir 4-Desfluoro Impurity
CAS No.
1863916-87-3
Chemical Name
Dolutegravir 4-Desfluoro Impurity
Synonyms
Dotiravir Impurity 2;Dotiravir Impurity 8;2-Fluoro Dolutegravir;4-Defluoro Dolutegravir;Dolutegravir Impurity 49;Dolutegravir Impurity 46;Doultegravir 2-F Impurity C;Dolutegravir 2-Fluoro Impurity;Dolutegravir 4-Desfluoro Impurity;Dolutegravir Impurity C (4-Defluoro Dolutegravir)
CBNumber
CB94796146
Molecular Formula
C20H20FN3O5
Formula Weight
401.39
MOL File
1863916-87-3.mol
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Dolutegravir 4-Desfluoro Impurity Property

Boiling point:
671.6±55.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
pka
4.50±1.00(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D228820
Product name
4-DefluoroDolutegravir
Packaging
2.5mg
Price
$445
Updated
2021/12/16
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Dolutegravir 4-Desfluoro Impurity Chemical Properties,Usage,Production

Uses

4-Defluro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 4-Desfluoro Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Dolutegravir 4-Desfluoro Impurity Suppliers

Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-010-52878169 15801002657
Email
sales@bjcomparison.com
Country
China
ProdList
4937
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ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18043
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Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
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021-64609160
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greensnown@163.com
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China
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9906
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Hubei Yangxin Medical Technology Co., Ltd.
Tel
15374522761
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QQ:2853117752
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3003392093@qq.com
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China
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8369
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Shanghai CR Corporation Limited
Tel
021-80270511; 4006653949
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QQ: 2136646215
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fred.wen@crcorporation.cn
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China
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CR Corporation Limited
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+8613062833949
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fred.wen@crcorporation.cn
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China
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sgtlifesciences pvt ltd
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+8617013299288
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dj@sgtlifesciences.com
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Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.
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Standardpharm Co. Ltd.
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86-714-3992388
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United States
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Jinan blalong chemical co. LTD
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2710913286@.com
Email
1513643261@qq.com
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1863916-87-3, Dolutegravir 4-Desfluoro ImpurityRelated Search:


  • Dolutegravir impurity 1/4-Defluoro Dolutegravir/(4R,12aS)-N-(2-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
  • (4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
  • 4-Defluoro Dolutegravir
  • 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
  • Dolutegravir Impurity C (4-Defluoro Dolutegravir)
  • Doultegravir 2-F Impurity C
  • Dolutegravir Impurity 46
  • Dolutegravir Impurity 49
  • 2-Fluoro Dolutegravir
  • Dolutegravir 2-Fluoro Impurity
  • Dolutegravir 4-Desfluoro Impurity
  • Dotiravir Impurity 2
  • Dotiravir Impurity 8
  • 1863916-87-3