Dolutegravir 2-Desfluoro Impurity

Product Name: Dolutegravir 2-Desfluoro Impurity
CAS No.: 1863916-88-4
Chemical Name: Dolutegravir 2-Desfluoro Impurity
Synonyms: 4-Fluoro Dolutegravir;Dolutegravir Impurity G;Dolutegravir Impurity 50;Dolutegravir Impurity 47;Dolutegravir 4-Fluoro Impurity;Dolutegravir 2-Desfluoro Impurity;(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity;Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
CBNumber: CB64796145
Molecular Formula: C20H20FN3O5
Formula Weight: 401.39
MOL File: 1863916-88-4.mol

More

Less

Dolutegravir 2-Desfluoro Impurity Property

Boiling point:: 675.7±55.0 °C(Predicted)
Density: 1.49±0.1 g/cm3(Predicted)
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 4.50±1.00(Predicted)
color: Off-White to Light Brown

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: D228715
Product name: DefluoroDolutegravir
Packaging: 10mg
Price: $1080
Updated: 2021/12/16

More

Less

Dolutegravir 2-Desfluoro Impurity Chemical Properties,Usage,Production

Uses

Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 2-Desfluoro Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Dolutegravir 2-Desfluoro Impurity Suppliers

China 25 India 6 Global 31

Shenzhen Roark Pharma-Tec Co., Ltd.

Tel: 13128912434
Email: 2880126944@qq.com
Country: China
ProdList: 2577
Advantage: 58

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-010-52878169 15801002657
Email: sales@bjcomparison.com
Country: China
ProdList: 5004
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Shanghai CR Corporation Limited

Tel: 021-80270511; 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 10044
Advantage: 58

CR Corporation Limited

Tel: +8613062833949
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 8647
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.

Tel: 020-89854820
Email: sales@jzpharma.cn
Country: China
ProdList: 1130
Advantage: 58

Nanjing zehe Pharmaceutical Technology Co., Ltd

Tel: 17768115366
Email: henry124604479@163.com
Country: China
ProdList: 255
Advantage: 58

Shenzhen Jianyi Biotechnology Co., Ltd

Tel: 0755-84826604
Email: 3001783715@qq.com
Country: CHINA
ProdList: 2896
Advantage: 58

Wuxi Helen Biotechnology Co., Ltd.,

Tel: 0510-85629785 18013409632
Fax: 0510-85625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 14081
Advantage: 58

1863916-88-4, Dolutegravir 2-Desfluoro ImpurityRelated Search:

Dolutegravir 4-Desfluoro Impurity IMpurity of Dolutegravir GSK1349572 Dolutegravir Impurity 3 Dolutegravir sodium Dolutegravir Impurity 6 O-Methyl Dolutegravir

2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity

Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

Dolutegravir Impurity G

Dolutegravir 2-Desfluoro Impurity

2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-

(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

Dolutegravir Impurity 47

Dolutegravir Impurity 50

4-Fluoro Dolutegravir

Dolutegravir 4-Fluoro Impurity

1863916-88-4