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Dolutegravir 4-Desfluoro Impurity

Product Name
Dolutegravir 4-Desfluoro Impurity
CAS No.
1863916-87-3
Chemical Name
Dolutegravir 4-Desfluoro Impurity
Synonyms
Dotiravir Impurity 2;Dotiravir Impurity 8;2-Fluoro Dolutegravir;4-Defluoro Dolutegravir;Dolutegravir Impurity 49;Dolutegravir Impurity 46;Doultegravir 2-F Impurity C;Dolutegravir 2-Fluoro Impurity;Dolutegravir 4-Desfluoro Impurity;Dolutegravir Impurity C (4-Defluoro Dolutegravir)
CBNumber
CB94796146
Molecular Formula
C20H20FN3O5
Formula Weight
401.39
MOL File
1863916-87-3.mol
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Dolutegravir 4-Desfluoro Impurity Property

Boiling point:
671.6±55.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
pka
4.50±1.00(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D228820
Product name
4-DefluoroDolutegravir
Packaging
2.5mg
Price
$445
Updated
2021/12/16
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Dolutegravir 4-Desfluoro Impurity Chemical Properties,Usage,Production

Uses

4-Defluro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 4-Desfluoro Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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Dolutegravir 4-Desfluoro Impurity Suppliers

China 26 India 5 United States 1 Global 32
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58

1863916-87-3, Dolutegravir 4-Desfluoro ImpurityRelated Search:

IMpurity of Dolutegravir Dolutegravir 2-Desfluoro Impurity GSK1349572 Dolutegravir Impurity 3 Dolutegravir sodium Dolutegravir Impurity 6 O-Methyl Dolutegravir

  • Dolutegravir impurity 1/4-Defluoro Dolutegravir/(4R,12aS)-N-(2-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
  • (4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
  • 4-Defluoro Dolutegravir
  • 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
  • Dolutegravir Impurity C (4-Defluoro Dolutegravir)
  • Doultegravir 2-F Impurity C
  • Dolutegravir Impurity 46
  • Dolutegravir Impurity 49
  • 2-Fluoro Dolutegravir
  • Dolutegravir 2-Fluoro Impurity
  • Dolutegravir 4-Desfluoro Impurity
  • Dotiravir Impurity 2
  • Dotiravir Impurity 8
  • 1863916-87-3