N-METHYLISATIN

Product Name: N-METHYLISATIN
CAS No.: 2058-74-4
Chemical Name: N-METHYLISATIN
Synonyms: OL-57;187287;NSC 42449;AKOS BC-1698;N-Methylsatin;1-METHYLISATIN;N-METHYLISATIN;1 METHYLISATINE;Methylisatintech;AKOS BBS-00000999
CBNumber: CB9480285
Molecular Formula: C9H7NO2
Formula Weight: 161.16
MOL File: 2058-74-4.mol

More

Less

N-METHYLISATIN Property

Melting point:: 130-133 °C (lit.)
Boiling point:: 287.44°C (rough estimate)
Density: 1.314
refractive index: 1.5050 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: -2.41±0.20(Predicted)
form: Crystalline Powder
color: Orange to brownish
Water Solubility: Insoluble in water.
λmax: 427nm(CH2Cl2)(lit.)
BRN: 128280
CAS DataBase Reference: 2058-74-4(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: T
Risk Statements: 25-37/38-41
Safety Statements: 26-39-45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: NL7939000
HazardClass: IRRITANT
HS Code: 29337900
Toxicity: mouse,LD50,intraperitoneal,685mg/kg (685mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION,Pharmaceutical Chemistry Journal Vol. 15, Pg. 858, 1981.

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 183075
Product name: 1-Methylisatin
Purity: 97%
Packaging: 1g
Price: $41.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 183075
Product name: 1-Methylisatin
Purity: 97%
Packaging: 10g
Price: $82.4
Updated: 2024/03/01

TCI Chemical

Product number: M2706
Product name: 1-Methylisatin
Purity: >98.0%(GC)
Packaging: 1g
Price: $31
Updated: 2024/03/01

TCI Chemical

Product number: M2706
Product name: 1-Methylisatin
Purity: >98.0%(GC)
Packaging: 5g
Price: $111
Updated: 2024/03/01

Alfa Aesar

Product number: A12942
Product name: 1-Methylisatin, 97%
Packaging: 1g
Price: $35.65
Updated: 2024/03/01

More

Less

N-METHYLISATIN Chemical Properties,Usage,Production

Chemical Properties

ORANGE TO BROWNISH CRYSTALLINE POWDER

Uses

1-Methylisatin is used as a reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones, for regioselective preparation of spirocyclic oxindole-butenolides, for synthesis of spiro-oxindoles, for preparation of unsymmetrical oxindoles, for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction, for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents.

Uses

Reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones
Reactant for regioselective preparation of spirocyclic oxindole-butenolides
Reactant for synthesis of spiro-oxindoles
Reactant for preparation of unsymmetrical oxindoles
Reactant for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction
Reactant for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents

Synthesis Reference(s)

Journal of Medicinal Chemistry, 47, p. 2089, 2004 DOI: 10.1021/jm030483s

General Description

The interaction between 1-methylisatin and human adult haemoglobin was studied using the circular dichroism (CD) spectroscopic, anisotropy and FTIR investigations.

N-METHYLISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-METHYLISATIN Suppliers

Americas 1 Belgium 3 China 85 Europe 1 France 1 Germany 7 India 14 Japan 2 Russia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 15 United States 26 Global 161

Apollo Scientific Ltd

Tel: --
Fax: --
Email: ales@apo
Country: United Kingdom
ProdList: 4521
Advantage: 58

Molekula Limited

Tel: --
Fax: --
Email: o@molekula.com
Country: United Kingdom
ProdList: 6127
Advantage: 58

Manchester Organics

Tel: --
Fax: --
Email: info@manchesterorganics.com
Country: United Kingdom
ProdList: 6834
Advantage: 67

Apollo Scientific Ltd.

Tel: --
Fax: --
Email: sales@apolloscientific.co.uk
Country: United Kingdom
ProdList: 6084
Advantage: 88

Hawks Scientific Ltd

Tel: --
Fax: --
Email: pete@hawks-scientific.com
Country: United Kingdom
ProdList: 2221
Advantage: 43

MOLEKULA Ltd.

Tel: --
Fax: --
Email: kevinbanks@molekula.com
Country: United Kingdom
ProdList: 6140
Advantage: 66

CARBONE SCIENTIFIC CO.,LTD

Tel: --
Fax: --
Email: sales@carbonesci.com
Country: United Kingdom
ProdList: 6666
Advantage: 30

ETA SCIENTIFIC Co.,Ltd

Tel: --
Fax: --
Email: sales@etascientific.com
Country: United Kingdom
ProdList: 6090
Advantage: 34

UK GREEN SCIENTIFIC CO.,LIMITED

Tel: --
Fax: --
Email: sales@gs-chem.com
Country: United Kingdom
ProdList: 6098
Advantage: 47

Fluorochem Ltd

Tel: --
Fax: --
Email: vernam@fluorochem.co.uk
Country: United Kingdom
ProdList: 6375
Advantage: 65

Eurolabs Limited

Tel: --
Fax: --
Country: United Kingdom
ProdList: 6309
Advantage: 46

Fulcrum Scientific Ltd.

Tel: --
Fax: --
Country: United Kingdom
ProdList: 6565
Advantage: 38

Fluorochem Ltd.

Tel: --
Fax: --
Email: enquiries@fluorochem.co.uk
Country: United Kingdom
ProdList: 6401
Advantage: 74

VWR International

Tel: --
Fax: --
Email: solutions@vwr.com
Country: United Kingdom
ProdList: 6548
Advantage: 82

Menai Organics Ltd.

Tel: --
Fax: --
Email: menaiorganics@compuserve.com
Country: United Kingdom
ProdList: 447
Advantage: 30

More

Less

View Lastest Price from N-METHYLISATIN manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Methylisatin 97% 2058-74-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: N-METHYLISATIN 2058-74-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kgs
Release date: 2020-01-29

2058-74-4, N-METHYLISATINRelated Search:

3-(1-methyl-1H-indole-3-carbonyl)hexanedioic acid (3R)-2,3-Dihydro-3-(2-propyn-1-ylaMino)-1H-inden-1-one 1-Methyl-1H-indole-3-carboxylic acid 1-Methylindole Ramosetron hydrochloride Rasagiline Impurity 5 Mesylate 5-(1-methyl-1H-indole-3-carbonyl)-1H-benzo[d]imidazol-2(3H)-one ramosetron 4,5,6,7-Tetrahydro-1H-benzoiMidazole-5-carboxylic acid hydrochloride Rasagiline Impurity 3 3a,7a-dihydroxy-5-(1-methyl-1H-indole-3-carbonyl)-hexahydro-1H-benzo[d]imidazol-2(3H)-one Ramosetron Impurity 13 N-[4,5,6,7-Tetrahydrobenzimidazole-5-yl)carbonyl] pyrrolidine sulfate 1-PHENYLISATIN 1-(Hydroxymethyl)indoline-2,3-dione N-METHYLISATIN 1,5-DIMETHYLINDOLINE-2,3-DIONE 5-CHLORO-7-METHYLISATIN

187287

1-methylindoline-2,3-dione

1-Methyl-2,3-dihydro-1H-indole-2,3-dione

OL-57

N-Methylindol-2,3-dione

1-Methylisatin,98%

N-Methylindoline-2,3-dione

1-Methyl-1H-indole-2,3-dione, 1-Methylindolin-2,3-dione

1-Methylisatin 97+%

1-Methylisatin 97%

NSC 42449

1H-Indole-2,3-dione, 1-methyl- (9CI)

1H-Indole-2,3-dione, 1-Methyl-

Indole-2,3-dione, 1-methyl-

Ramosetron Impurity 1

1-methyl-1h-indole-3-dione

1-methyl-indole-2,3-dione

1-methyl-indole-3-dione

1-METHYL-1H-INDOLE-2,3-DIONE

1 METHYLISATINE

1-METHYLISATIN

N-METHYLISATIN

TIMTEC-BB SBB006835

1-methyl-2,3-dihydroindole-2,3-dione

Methylisatintech

N-Methylsatin

N-Methylisatin, tech.

N-Methylisatin 98%

AKOS BBS-00000999

AKOS BC-1698

1-Methylisatin, 97%, for synthesis

1-Methylisatin &gt

1-Methylindoline-2,3-dione (Ramosetron Impurity)

2058-74-4

Indoles

Heterocyclic Building Blocks

Building Blocks

Heterocycles

Building Blocks

Heterocyclic Building Blocks

Indoles

pharmacetical