N-METHYLISATIN

Product Name: N-METHYLISATIN
CAS No.: 2058-74-4
Chemical Name: N-METHYLISATIN
Synonyms: OL-57;187287;NSC 42449;AKOS BC-1698;N-Methylsatin;1-METHYLISATIN;N-METHYLISATIN;1 METHYLISATINE;Methylisatintech;AKOS BBS-00000999
CBNumber: CB9480285
Molecular Formula: C9H7NO2
Formula Weight: 161.16
MOL File: 2058-74-4.mol

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N-METHYLISATIN Property

Melting point:: 130-133 °C (lit.)
Boiling point:: 287.44°C (rough estimate)
Density: 1.314
refractive index: 1.5050 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: -2.41±0.20(Predicted)
form: Crystalline Powder
color: Orange to brownish
Water Solubility: Insoluble in water.
λmax: 427nm(CH2Cl2)(lit.)
BRN: 128280
CAS DataBase Reference: 2058-74-4(CAS DataBase Reference)

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Safety

Hazard Codes: T
Risk Statements: 25-37/38-41
Safety Statements: 26-39-45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: NL7939000
HazardClass: IRRITANT
HS Code: 29337900
Toxicity: mouse,LD50,intraperitoneal,685mg/kg (685mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION,Pharmaceutical Chemistry Journal Vol. 15, Pg. 858, 1981.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 183075
Product name: 1-Methylisatin
Purity: 97%
Packaging: 1g
Price: $41.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 183075
Product name: 1-Methylisatin
Purity: 97%
Packaging: 10g
Price: $82.4
Updated: 2024/03/01

TCI Chemical

Product number: M2706
Product name: 1-Methylisatin
Purity: >98.0%(GC)
Packaging: 1g
Price: $31
Updated: 2024/03/01

TCI Chemical

Product number: M2706
Product name: 1-Methylisatin
Purity: >98.0%(GC)
Packaging: 5g
Price: $111
Updated: 2024/03/01

Alfa Aesar

Product number: A12942
Product name: 1-Methylisatin, 97%
Packaging: 1g
Price: $35.65
Updated: 2024/03/01

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N-METHYLISATIN Chemical Properties,Usage,Production

Chemical Properties

ORANGE TO BROWNISH CRYSTALLINE POWDER

Uses

1-Methylisatin is used as a reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones, for regioselective preparation of spirocyclic oxindole-butenolides, for synthesis of spiro-oxindoles, for preparation of unsymmetrical oxindoles, for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction, for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents.

Uses

Reactant for stereoselective preparation of spirobicyclic and bis-spirotricyclic pyrazolidinones
Reactant for regioselective preparation of spirocyclic oxindole-butenolides
Reactant for synthesis of spiro-oxindoles
Reactant for preparation of unsymmetrical oxindoles
Reactant for stereoselective preparation of hydroxyloxindoles via Morita-Baylis-Hillman reaction
Reactant for preparation of pyridinecarboxylic acid [(oxo)indolylidene)hydrazide derivatives (Schiff base hydrazides) as antibacterial agents

Synthesis Reference(s)

Journal of Medicinal Chemistry, 47, p. 2089, 2004 DOI: 10.1021/jm030483s

General Description

The interaction between 1-methylisatin and human adult haemoglobin was studied using the circular dichroism (CD) spectroscopic, anisotropy and FTIR investigations.

N-METHYLISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHYLISATIN Suppliers

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View Lastest Price from N-METHYLISATIN manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-Methylisatin 97% 2058-74-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: N-METHYLISATIN 2058-74-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kgs
Release date: 2020-01-29

2058-74-4, N-METHYLISATINRelated Search:

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AKOS BC-1698

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2058-74-4

Indoles

Heterocyclic Building Blocks

Building Blocks

Heterocycles

Building Blocks

Heterocyclic Building Blocks

Indoles

pharmacetical