Axitinib-13C-d3

Product Name: Axitinib-13C-d3
CAS No.: 1261432-00-1
Chemical Name: Axitinib-13C-d3
Synonyms: Axitinib-13C-d3;[13C,2H3]-Axitinib;(E)-N-(methyl-13C-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide
CBNumber: CB94814349
Formula Weight: 0
MOL File: Mol file

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Axitinib-13C-d3 Property

storage temp.: Store at -20°C
solubility: DMSO: soluble
form: A solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26676
Product name: Axitinib-13C-d3
Packaging: 500μg
Price: $605
Updated: 2024/03/01

Cayman Chemical

Product number: 26676
Product name: Axitinib-13C-d3
Packaging: 1mg
Price: $1151
Updated: 2024/03/01

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Axitinib-13C-d3 Chemical Properties,Usage,Production

Description

Axitinib-13C-d3 is intended for use as an internal standard for the quantification of axitinib by GC- or LC-MS. Axitinib is a VEGFR inhibitor (IC₅₀s = 1.2, 0.25, and 0.29 nM for VEGFR1, -2, and -3, respectively). It also inhibits c-Kit and PDGFRβ (IC₅₀s = 1.7 and 1.6 nM, respectively). It inhibits VEGF-induced migration of and tube formation by human umbilical vein endothelial cells (HUVECs). Axitinib (1-100 mg/kg) reduces microvessel density, a marker of angiogenesis, and tumor growth in MV522 colon carcinoma, A375 melanoma, SN12C-GFP renal carcinoma, and U87 glioma mouse xenograft models in a dose-dependent manner. Formulations containing axitinib have been used in the treatment of renal cell carcinoma.

Axitinib-13C-d3 Preparation Products And Raw materials

Raw materials

Preparation Products

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Axitinib-13C-d3 Suppliers

CHINA 14 India 3 United States 2 Global 19

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1261432-00-1, Axitinib-13C-d3Related Search:

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Axitinib-13C-d3

[13C,2H3]-Axitinib

(E)-N-(methyl-13C-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide

1261432-00-1