ChemicalBook > CAS DataBase List > SORAFENIB N-OXIDE

SORAFENIB N-OXIDE

Product Name
SORAFENIB N-OXIDE
CAS No.
583840-03-3
Chemical Name
SORAFENIB N-OXIDE
Synonyms
SORAFENIB N-OXIDE;Sorafenib impurities11;Sorafenib impurities172;Sorafenib N-oxide;Sorafenib Impurity 27(Sorafenib N-Oxide);4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine 1-oxide;4-[4-[[[[4-Chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-2-pyridinecarboxaMide 1-Oxide;2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-, 1-oxide;Sorafenib impurity 23/Sorafenib N-Oxide/4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine 1-oxide
CBNumber
CB9496866
Molecular Formula
C21H16ClF3N4O4
Formula Weight
480.82
MOL File
583840-03-3.mol
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SORAFENIB N-OXIDE Property

Melting point:
220-222oC
Boiling point:
591.7±50.0 °C(Predicted)
Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO: soluble; Methanol: very slightly soluble, heated
form 
A solid
pka
12.89±0.70(Predicted)
color 
white to off-white
biological source
synthetic
Major Application
clinical research
general analytical
life science and biopharma
metabolomics
InChI
1S/C21H16ClF3N4O4/c1-26-19(30)18-11-15(8-9-29(18)32)33-14-5-2-12(3-6-14)27-20(31)28-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,27,28,31)
InChIKey
BQAZCCVUZDIZDC-UHFFFAOYSA-N
SMILES
CNC(=O)C1=[N+](C=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)[O-]
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Safety

WGK Germany 
WGK 3
Storage Class
10 - Combustible liquids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27830
Product name
Sorafenib N-oxide
Packaging
1mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
27830
Product name
Sorafenib N-oxide
Packaging
5mg
Price
$392
Updated
2024/03/01
Usbiological
Product number
289166
Product name
Sorafenib N-oxide
Packaging
2mg
Price
$495
Updated
2021/12/16
TRC
Product number
S676870
Product name
SorafenibN-Oxide
Packaging
5mg
Price
$215
Updated
2021/12/16
AK Scientific
Product number
3391CR
Product name
SorafenibN-Oxide
Packaging
1mg
Price
$233
Updated
2021/12/16
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SORAFENIB N-OXIDE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

A metabolite of Sorafenib, a potent Raf kinase inhibitor.

SORAFENIB N-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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SORAFENIB N-OXIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7440
Advantage
65
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5157
Advantage
50
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
Taizhou Tongxin Bio-Tech Co., Ltd
Tel
0523-86818997 18652728585
Email
sales@allyrise.com
Country
China
ProdList
2989
Advantage
60
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
Quality Control Solutions Ltd.
Tel
66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18390
Advantage
56
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50

583840-03-3, SORAFENIB N-OXIDERelated Search:


  • Sorafenib impurity 23/Sorafenib N-Oxide/4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine 1-oxide
  • SORAFENIB N-OXIDE
  • 4-[4-[[[[4-Chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-2-pyridinecarboxaMide 1-Oxide
  • Sorafenib Impurity 27(Sorafenib N-Oxide)
  • 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-, 1-oxide
  • 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine 1-oxide
  • Sorafenib impurities172
  • Sorafenib impurities11
  • Sorafenib <i>N</i>-oxide
  • 583840-03-3
  • C21H16ClF3N4O4
  • Metabolites
  • Various Metabolites and Impurities