3,5-Dibromopyridine-4-carboxaldehyde
- Product Name
- 3,5-Dibromopyridine-4-carboxaldehyde
- CAS No.
- 70201-42-2
- Chemical Name
- 3,5-Dibromopyridine-4-carboxaldehyde
- Synonyms
- 3,5-Dibromoisonicotinaldehyde;3,5-Dibromo-4-pyridinecarboxaldehyde;3,5-DibromoisonicotinaL;3,5-Dibromo-4-formylpyridine;3,5-Dibromo-4-pyridinecarbaldehyde;3,5-Dibromopyridine-4-carbaldehyde;5-Dibromo-4-pyridinecarboxaldehyde;3,5-Dibromopyridine-4-carboxaldehyde;4-PYRIDINECARBOXALDEHYDE, 3,5-DIBROMO-;3,5-DibroMo-4-pyridinecarboxaldehyde 97%
- CBNumber
- CB9500149
- Molecular Formula
- C6H3Br2NO
- Formula Weight
- 264.9
- MOL File
- 70201-42-2.mol
3,5-Dibromopyridine-4-carboxaldehyde Property
- Melting point:
- 118-122 °C (lit.)
- Boiling point:
- 278.1±35.0 °C(Predicted)
- Density
- 2.090±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- Choroform (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- -1.47±0.28(Predicted)
- color
- Pale Yellow to Light Yellow
- InChI
- InChI=1S/C6H3Br2NO/c7-5-1-9-2-6(8)4(5)3-10/h1-3H
- InChIKey
- WPBYVMDYYFWYAY-UHFFFAOYSA-N
- SMILES
- C1=NC=C(Br)C(C=O)=C1Br
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-43
- Safety Statements
- 26-36/37
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 646113
- Product name
- 3,5-Dibromo-4-pyridinecarboxaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $48
- Updated
- 2023/06/20
- Product number
- 646113
- Product name
- 3,5-Dibromo-4-pyridinecarboxaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $129
- Updated
- 2023/06/20
- Product number
- D4674
- Product name
- 3,5-Dibromo-4-pyridinecarboxaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 1g
- Price
- $34
- Updated
- 2025/07/31
- Product number
- D4674
- Product name
- 3,5-Dibromo-4-pyridinecarboxaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $77
- Updated
- 2025/07/31
- Product number
- 44724
- Product name
- 3,5-Dibromo-4-pyridinecarboxaldehyde,≥97%(GC)
- Purity
- ≥97%(GC)
- Packaging
- 1G
- Price
- $45.27
- Updated
- 2021/12/16
3,5-Dibromopyridine-4-carboxaldehyde Chemical Properties,Usage,Production
Uses
3,5-Dibromo-4-pyridinecarboxaldehyde is easily soluble in water and miscible with organic solvents. It is used as an intermediate for synthesising the insecticide pyrazinone and in textiles to improve the stiffness of cotton fabrics.
Synthesis
625-92-3
107-31-3
70201-42-2
Step 1: Diisopropylamine (2.4 g, 24.0 mmol) was dissolved in anhydrous tetrahydrofuran (20 mL) under nitrogen protection and cooled to 0 °C. A n-butyllithium solution (9.6 mL, 24.0 mmol) in hexane was slowly added dropwise and stirred continuously for 30 min at this temperature. Subsequently, additional anhydrous tetrahydrofuran (30 mL) was added and the reaction mixture was further cooled to -78 °C. To this low-temperature solution, dry 3,5-dibromopyridine (4.7 g, 20 mmol) was added, diluted dropwise with tetrahydrofuran (50 mL), and stirring was continued for 30 minutes. Next, methyl formate (2.4 g, 40 mmol) was added and the reaction mixture was continued stirring at -78 °C for 30 min. After slowly warming to room temperature, the reaction was quenched with saturated sodium bicarbonate solution (100 mL) and extracted with ethyl acetate (50 mL × 3). The organic phases were combined, dried over anhydrous sodium sulfate, concentrated and purified by column chromatography to afford the target product 3,5-dibromopyridine-4-carbaldehyde (26-b) as a light yellow solid (4.0 g, 75% yield).1H NMR (300 MHz, DMSO-d6) δ: 10.06 (s, 1H), 8.87 (s, 2H).
References
[1] Patent: US2017/158680, 2017, A1. Location in patent: Paragraph 0418; 0419; 0420
[2] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 10, p. 2789 - 2794
[3] Journal of Fluorine Chemistry, 2006, vol. 127, # 6, p. 755 - 759
[4] Patent: US6232320, 2001, B1
3,5-Dibromopyridine-4-carboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
3,5-Dibromopyridine-4-carboxaldehyde Suppliers
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- Switzerland
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View Lastest Price from 3,5-Dibromopyridine-4-carboxaldehyde manufacturers
- Product
- 3,5-Dibromopyridine-4-carboxaldehyde 70201-42-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-30
- Product
- 3,5-Dibromopyridine-4-carboxaldehyde 70201-42-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-14
- Product
- 3,5-Dibromopyridine-4-carboxaldehyde 70201-42-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98.0%
- Supply Ability
- 1000kg
- Release date
- 2023-04-05