3,N4-ETHENOCYTOSINE

Product Name: 3,N4-ETHENOCYTOSINE
CAS No.: 55662-66-3
Chemical Name: 3,N4-ETHENOCYTOSINE
Synonyms: 3,n(4)-ethanocytosine;imidazo[1,2-c]pyrimidin-5-ol;imidazo[1,2-f]pyrimidin-5-ol;IMidazo[1,2-c]pyriMidin-5(6H)-one
CBNumber: CB9503443
Molecular Formula: C6H5N3O
Formula Weight: 135.12
MOL File: 55662-66-3.mol

More

Less

3,N4-ETHENOCYTOSINE Property

Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 7.09±0.20(Predicted)
Appearance: Light brown to brown Solid

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: NUC0003911
Product name: 3,N4-ETHENOCYTOSINE
Purity: 95.00%
Packaging: 5MG
Price: $505.07
Updated: 2021/12/16

Crysdot

Product number: CD11104848
Product name: Imidazo[1,2-c]pyrimidin-5(6H)-one
Purity: 95+%
Packaging: 1g
Price: $579
Updated: 2021/12/16

Ambeed

Product number: A123740
Product name: Imidazo[1,2-c]pyrimidin-5(6H)-one
Purity: 95%
Packaging: 100mg
Price: $43
Updated: 2021/12/16

Ambeed

Product number: A123740
Product name: Imidazo[1,2-c]pyrimidin-5(6H)-one
Purity: 95%
Packaging: 250mg
Price: $60
Updated: 2021/12/16

Chemenu

Product number: CM253640
Product name: Imidazo[1,2-c]pyrimidin-5(6H)-one
Purity: 95+%
Packaging: 100mg
Price: $84
Updated: 2021/12/16

More

Less

3,N4-ETHENOCYTOSINE Chemical Properties,Usage,Production

Definition

ChEBI: 3,N(4)-ethenocytosine is an organic heterobicyclic compound. It has a role as a mutagen. It is functionally related to a cytosine. It derives from a hydride of an imidazo[1,2-c]pyrimidine.

Synthesis

107-20-0

71-30-7

55662-66-3

Procedure for the synthesis of imidazo[1,2-c]pyrimidin-5(6H)-one (13): 50% aqueous chloroacetaldehyde (0.686 mL, 5.40 mmol) was added to a stirred solution of 6-aminopyrimidin-2(1H)-one (500 mg, 4.50 mmol) in N,N-dimethylformamide (DMF, 10 mL). The reaction mixture was stirred at 70 °C for 16 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was washed with ethanol and ether to afford the target compound 13 as a light brown powder (320 mg, 53% yield). Thin layer chromatography (TLC) analysis showed Rf = 0.47 (unfolding agent: ethyl acetate/methanol, 4:1). The melting point of the product was 281-282 °C. Nuclear magnetic resonance hydrogen spectrum (1H NMR, 400 MHz, [D6]DMSO): δ = 6.62 (d, 1H, 3J = 7.6 Hz), 7.28 (d, 1H, 3J = 7.6 Hz), 7.41 (d, 1H, 3J = 1.2 Hz), 7.80 (d, 1H, 3J = 1.2 Hz), 11.6 (bs, 1H). Nuclear magnetic resonance carbon spectrum (13C NMR, 100 MHz, [D6]DMSO): δ = 97.7, 112.2, 129.4, 132.3, 145.9, 146.4. infrared spectrum (IR, KBr): ν = 3451, 3121, 3096, 1718, 1630, 1547, 1290, 1252, 1111 cm- 1. mass spectrum (ESI-MS): m/z 135.8 [M + H]+.

References

[1] Tetrahedron, 2014, vol. 71, # 1, p. 27 - 36
[2] Patent: WO2017/20944, 2017, A1. Location in patent: Page/Page column 16-17

3,N4-ETHENOCYTOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3,N4-ETHENOCYTOSINE Suppliers

China 24 India 1 Switzerland 1 United States 3 Global 29

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

Mashilabs (Shanghai) Co.,Ltd.

Tel: 19916721580
Fax: QQ：3154870176
Email: mafarm@126.com
Country: China
ProdList: 4542
Advantage: 58

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 0086-15250997978
Fax: 025-58362220
Email: sale@njxizebio.com
Country: China
ProdList: 4855
Advantage: 55

Shanghai TuZhi Chemical Co., Ltd.

Tel: 19542790274
Fax: QQ1456295541
Email: 2119559397@qq.com
Country: China
ProdList: 753
Advantage: 50

Biokitchen

Tel: 021-021-021-31663258 13795219287
Fax: 021-31663258
Email: donghuanwen@126.com
Country: China
ProdList: 8816
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Birdo (Shanghai) Medical Technology Co., Ltd.

Tel: 021-58099077-8041 18601625411
Email: sales@birdotech.com
Country: China
ProdList: 9764
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Shanghai Sunmonth Technology Co., LTD

Tel: 15216675652
Email: xuanyuelj@163.com
Country: China
ProdList: 2864
Advantage: 58

55662-66-3, 3,N4-ETHENOCYTOSINERelated Search:

6-AMINO-IMIDAZO[1,2-A]PYRIMIDINE Imidazo[1,2-a]pyrimidine Imidazo[1,5-a]pyridine Methyl iMidazo[1,2-b]pyridazine-6-carboxylate ETHENO-2'-DEOXYCYTIDINE 3,N4-ETHENOCYTOSINE 2-VINYLIMIDAZOLE 1H-Imidazole-1-carboxaldehyde ETHENOCYTIDINE ETHENOCYTIDINE, [3H]- methyl imidazo[1,2-a]pyrimidine-5-carboxylate imidazo[1,2-c]pyrimidine-7-carboxylic acid Imidazo[1,2-a]pyrimidine-7-carboxylic acid methyl ester

3,n(4)-ethanocytosine

imidazo[1,2-c]pyrimidin-5-ol

IMidazo[1,2-c]pyriMidin-5(6H)-one

imidazo[1,2-f]pyrimidin-5-ol

55662-66-3