Imidazo[1,2-a]pyrimidine

Product Name: Imidazo[1,2-a]pyrimidine
CAS No.: 274-95-3
Chemical Name: Imidazo[1,2-a]pyrimidine
Synonyms: 1,3a,7-Triazaindene;1,8-Diazaindolizine;IMIDAZO[1,2-A]PYRIMIDINE;Imidazo[1,2-a]pyrimidine>Imidazolo [1,2-a] pyrimidine;Imidazo[1,2-a]pyrimidine (7CI, 8CI, 9CI, ACI)
CBNumber: CB8479071
Molecular Formula: C6H5N3
Formula Weight: 119.12
MOL File: 274-95-3.mol

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Imidazo[1,2-a]pyrimidine Property

Melting point:: 127-129°
Density: 1.29±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 5.50±0.30(Predicted)
color: Light yellow to Brown
InChI: InChI=1S/C6H5N3/c1-2-7-6-8-3-5-9(6)4-1/h1-5H
InChIKey: INSWZAQOISIYDT-UHFFFAOYSA-N
SMILES: C12=NC=CN1C=CC=N2
CAS DataBase Reference: 274-95-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37
HazardClass: IRRITANT
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: I0798
Product name: Imidazo[1,2-a]pyrimidine
Purity: >98.0%(GC)
Packaging: 1g
Price: $153
Updated: 2023/01/07

TCI Chemical

Product number: I0798
Product name: Imidazo[1,2-a]pyrimidine
Purity: >98.0%(GC)
Packaging: 5g
Price: $537
Updated: 2023/01/07

TRC

Product number: I387598
Product name: Imidazo[1,2-a]pyrimidine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: I387598
Product name: Imidazo[1,2-a]pyrimidine
Packaging: 500mg
Price: $110
Updated: 2021/12/16

AK Scientific

Product number: J55553
Product name: Imidazo[1,2-a]pyrimidine
Packaging: 1g
Price: $40
Updated: 2021/12/16

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Imidazo[1,2-a]pyrimidine Chemical Properties,Usage,Production

Uses

Imidazo[1,2-a]pyrimidine is a heterocyclic aromatic compound used as a pharmaceutical intermediate ingredient, organic solvent and chemical reaction reagent. In the field of agrochemicals, it interacts with key enzymes such as acetylcholinesterase, lipoxygenase and glutathione-S-transferase. In the dye industry, it has been found to interact with a variety of proteins, including cytochrome P450 and peroxidase, making it an important component in dye formulations.

Synthesis

109-12-6

2032-35-1

274-95-3

In a 250-mL three-necked round-bottomed flask, 2-aminopyrimidine (5 g, 0.052 mol), bromoacetaldehyde diethyl acetal (20.7 g, 0.104 mol), 48% aqueous hydrobromic acid (5 mL), and ethanol (50 mL) were added sequentially. The reaction mixture was stirred at room temperature for 18 hours. After completion of the reaction, the reaction solution was cooled to room temperature. Subsequently, the reaction mixture was adsorbed onto silica gel and purified by column chromatography (eluent: dichloromethane/methanol), resulting in 5 g of imidazo[1,2-a]pyrimidine in about XX% yield.

References

[1] Patent: KR2017/126059, 2017, A. Location in patent: Paragraph 0069; 0072; 0073; 0076; 0077

Imidazo[1,2-a]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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Imidazo[1,2-a]pyrimidine Suppliers

Americas 1 China 155 Europe 1 Germany 2 Hungary 1 India 2 Japan 1 United Kingdom 5 United States 22 Global 190

Alichem(Changzhou) Co., Ltd.

Tel: 19941333411
Fax: QQ:749741756
Email: sales@alichem.cn
Country: China
ProdList: 523
Advantage: 58

Nanjing Jubai Biomedical Technology Co., Ltd.

Tel: 13585203734
Email: info@jbzml.com
Country: China
ProdList: 99
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Carbott PharmTech Inc.

Tel: 0535-6385396
Fax: +86 (535) 638-9971
Email: info@carbottpharm.com
Country: China
ProdList: 957
Advantage: 56

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
ProdList: 882
Advantage: 52

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View Lastest Price from Imidazo[1,2-a]pyrimidine manufacturers

Henan Fengda Chemical Co., Ltd

Product: 1,3a,7-triazaindene 274-95-3
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-02

Shanghai Rlavie Technology Co ltd

Product: Imidazo[1,2-a]pyrimidine 274-95-3
Price: US $0.00-0.00/kg
Min. Order: 0.0001kg
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2022-05-10

Honest Joy Holdings Limited

Product: Imidazo[1,2-a]pyrimidine 274-95-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.0%
Supply Ability: 100 tons
Release date: 2022-02-18

274-95-3, Imidazo[1,2-a]pyrimidineRelated Search:

Silver sulfadiazine Fluorocytosine Pyrimidine Levamisole Sulfadiazine Mebendazole Methimazole IMIDAZO[1,2-A]PYRIMIDINE-2-CARBOXYLIC ACID ETHYL ESTER IMIDAZO[1,2-A]PYRIDIN-8-YLAMINE Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester METHYL IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLATE 6-(Hydroxymethyl)imidazo[1,2-a]pyridine 6-AMINO-IMIDAZO[1,2-A]PYRIMIDINE 3,N4-ETHENOCYTOSINE Imidazo[1,2-b]pyridazine-3-carboxaldehyde (9CI) Methyl imidazo[1,2-a]pyridine-5-carboxylate IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE

1,8-Diazaindolizine

1,3a,7-Triazaindene

IMIDAZO[1,2-A]PYRIMIDINE

Imidazo[1,2-a]pyrimidine&gt

Imidazo[1,2-a]pyrimidine (7CI, 8CI, 9CI, ACI)

Imidazolo [1,2-a] pyrimidine

274-95-3

Fused Ring Systems

Pyrimidines

Heterocycle-Pyrimidine series

Fluorobenzene