6-(Hydroxymethyl)imidazo[1,2-a]pyridine
- Product Name
- 6-(Hydroxymethyl)imidazo[1,2-a]pyridine
- CAS No.
- 132213-07-1
- Chemical Name
- 6-(Hydroxymethyl)imidazo[1,2-a]pyridine
- Synonyms
- IMidazo[1,2-a]pyridine-6-Methanol;IMIDAZO[1,2-A]PYRIDIN-6-YLMETHANOL;IMidazo(1,2-a)pyridine-6-ylMethanol;(H-iMidazo[1,2-a]pyridin-6-yl)Methanol;6-(Hydroxymethyl)imidazo[1,2-a]pyridine;6-(Hydroxymethyl)imidazo[1,2-a]pyridine97%;6-(Hydroxymethyl)imidazo[1,2-a]pyridine 97%;Imidazo[1,2-a]pyridine-6-methanol (9CI, ACI)
- CBNumber
- CB7741793
- Molecular Formula
- C8H8N2O
- Formula Weight
- 148.16
- MOL File
- 132213-07-1.mol
6-(Hydroxymethyl)imidazo[1,2-a]pyridine Property
- Melting point:
- 105-107
- Density
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 13.36±0.10(Predicted)
- form
- solid
- color
- Beige
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-26-36/37/39
- Hazard Note
- Irritant
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-11248
- Product name
- IMIDAZO[1,2-A]PYRIDIN-6-YLMETHANOL
- Purity
- 97%
- Packaging
- 250mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- BP-11248
- Product name
- IMIDAZO[1,2-A]PYRIDIN-6-YLMETHANOL
- Purity
- 97%
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 4H01-1-T5
- Product name
- 6-(Hydroxymethyl)imidazo[1,2-a]pyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $119
- Updated
- 2021/12/16
- Product number
- 074011
- Product name
- Imidazo[1,2-a]pyridin-6-ylmethanol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $197
- Updated
- 2021/12/16
- Product number
- 4H01-1-T5
- Product name
- 6-(Hydroxymethyl)imidazo[1,2-a]pyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $42
- Updated
- 2021/12/16
6-(Hydroxymethyl)imidazo[1,2-a]pyridine Chemical Properties,Usage,Production
Definition
ChEBI: Imidazo[1,2-a]pyridin-6-ylmethanol is an imidazopyridine.
Synthesis
139022-25-6
132213-07-1
To a solution of imidazo[1,2-a]pyridine-6-carboxylic acid (4.3 g, 27 mmol) in anhydrous tetrahydrofuran (25 mL) was added slowly and dropwise borane dimethyl sulfide complex (5.8 mL, 10 N, in dimethyl sulfide, 58 mmol) at 0 °C. The reaction mixture was stirred at 0 °C for 0.5 h, then warmed up to 80 °C and kept stirring for 3 h. The reaction mixture was then stirred for 0.5 h. The reaction mixture was cooled down to 0.5 °C. Upon completion of the reaction, the mixture was cooled to 0 °C, carefully quenched with methanol (10 mL) and subsequently concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with an eluent ratio of dichloromethane: methanol = 10:1 to afford imidazo[1,2-a]pyridine-6-methanol (1.0 g, 26% yield) as a white solid.LCMS analysis resulted in (ES+) m/z (M+H)+ = 149.1 and retention time tR = 0.279 min.
References
[1] Patent: WO2015/66371, 2015, A1. Location in patent: Paragraph 00530-00531
6-(Hydroxymethyl)imidazo[1,2-a]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-(Hydroxymethyl)imidazo[1,2-a]pyridine manufacturers
- Product
- 6-(Hydroxymethyl)imidazo[1,2-a]pyridine 132213-07-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons/month
- Release date
- 2020-01-08