ChemicalBook > CAS DataBase List > 6-(Hydroxymethyl)imidazo[1,2-a]pyridine

6-(Hydroxymethyl)imidazo[1,2-a]pyridine

Product Name
6-(Hydroxymethyl)imidazo[1,2-a]pyridine
CAS No.
132213-07-1
Chemical Name
6-(Hydroxymethyl)imidazo[1,2-a]pyridine
Synonyms
IMidazo[1,2-a]pyridine-6-Methanol;IMIDAZO[1,2-A]PYRIDIN-6-YLMETHANOL;IMidazo(1,2-a)pyridine-6-ylMethanol;(H-iMidazo[1,2-a]pyridin-6-yl)Methanol;6-(Hydroxymethyl)imidazo[1,2-a]pyridine;6-(Hydroxymethyl)imidazo[1,2-a]pyridine97%;6-(Hydroxymethyl)imidazo[1,2-a]pyridine 97%;Imidazo[1,2-a]pyridine-6-methanol (9CI, ACI)
CBNumber
CB7741793
Molecular Formula
C8H8N2O
Formula Weight
148.16
MOL File
132213-07-1.mol
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6-(Hydroxymethyl)imidazo[1,2-a]pyridine Property

Melting point:
105-107
Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
13.36±0.10(Predicted)
form 
solid
color 
Beige
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-26-36/37/39
Hazard Note 
Irritant
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-11248
Product name
IMIDAZO[1,2-A]PYRIDIN-6-YLMETHANOL
Purity
97%
Packaging
250mg
Price
$59
Updated
2021/12/16
BroadPharm
Product number
BP-11248
Product name
IMIDAZO[1,2-A]PYRIDIN-6-YLMETHANOL
Purity
97%
Packaging
500mg
Price
$110
Updated
2021/12/16
SynQuest Laboratories
Product number
4H01-1-T5
Product name
6-(Hydroxymethyl)imidazo[1,2-a]pyridine
Purity
97%
Packaging
1g
Price
$119
Updated
2021/12/16
Matrix Scientific
Product number
074011
Product name
Imidazo[1,2-a]pyridin-6-ylmethanol
Purity
95+%
Packaging
1g
Price
$197
Updated
2021/12/16
SynQuest Laboratories
Product number
4H01-1-T5
Product name
6-(Hydroxymethyl)imidazo[1,2-a]pyridine
Purity
97%
Packaging
250mg
Price
$42
Updated
2021/12/16
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6-(Hydroxymethyl)imidazo[1,2-a]pyridine Chemical Properties,Usage,Production

Definition

ChEBI: Imidazo[1,2-a]pyridin-6-ylmethanol is an imidazopyridine.

Synthesis

139022-25-6

132213-07-1

To a solution of imidazo[1,2-a]pyridine-6-carboxylic acid (4.3 g, 27 mmol) in anhydrous tetrahydrofuran (25 mL) was added slowly and dropwise borane dimethyl sulfide complex (5.8 mL, 10 N, in dimethyl sulfide, 58 mmol) at 0 °C. The reaction mixture was stirred at 0 °C for 0.5 h, then warmed up to 80 °C and kept stirring for 3 h. The reaction mixture was then stirred for 0.5 h. The reaction mixture was cooled down to 0.5 °C. Upon completion of the reaction, the mixture was cooled to 0 °C, carefully quenched with methanol (10 mL) and subsequently concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with an eluent ratio of dichloromethane: methanol = 10:1 to afford imidazo[1,2-a]pyridine-6-methanol (1.0 g, 26% yield) as a white solid.LCMS analysis resulted in (ES+) m/z (M+H)+ = 149.1 and retention time tR = 0.279 min.

References

[1] Patent: WO2015/66371, 2015, A1. Location in patent: Paragraph 00530-00531

6-(Hydroxymethyl)imidazo[1,2-a]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-(Hydroxymethyl)imidazo[1,2-a]pyridine manufacturers

Career Henan Chemical Co
Product
6-(Hydroxymethyl)imidazo[1,2-a]pyridine 132213-07-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons/month
Release date
2020-01-08

132213-07-1, 6-(Hydroxymethyl)imidazo[1,2-a]pyridineRelated Search:

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