ChemicalBook > CAS DataBase List > Imidazo[1,2-a]pyrimidine

Imidazo[1,2-a]pyrimidine

Product Name
Imidazo[1,2-a]pyrimidine
CAS No.
274-95-3
Chemical Name
Imidazo[1,2-a]pyrimidine
Synonyms
1,3a,7-Triazaindene;1,8-Diazaindolizine;IMIDAZO[1,2-A]PYRIMIDINE;Imidazo[1,2-a]pyrimidine>Imidazolo [1,2-a] pyrimidine;Imidazo[1,2-a]pyrimidine (7CI, 8CI, 9CI, ACI)
CBNumber
CB8479071
Molecular Formula
C6H5N3
Formula Weight
119.12
MOL File
274-95-3.mol
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Imidazo[1,2-a]pyrimidine Property

Melting point:
127-129°
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
5.50±0.30(Predicted)
color 
Light yellow to Brown
InChI
InChI=1S/C6H5N3/c1-2-7-6-8-3-5-9(6)4-1/h1-5H
InChIKey
INSWZAQOISIYDT-UHFFFAOYSA-N
SMILES
C12=NC=CN1C=CC=N2
CAS DataBase Reference
274-95-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
HazardClass 
IRRITANT
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
I0798
Product name
Imidazo[1,2-a]pyrimidine
Purity
>98.0%(GC)
Packaging
1g
Price
$153
Updated
2023/01/07
TCI Chemical
Product number
I0798
Product name
Imidazo[1,2-a]pyrimidine
Purity
>98.0%(GC)
Packaging
5g
Price
$537
Updated
2023/01/07
TRC
Product number
I387598
Product name
Imidazo[1,2-a]pyrimidine
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
I387598
Product name
Imidazo[1,2-a]pyrimidine
Packaging
500mg
Price
$110
Updated
2021/12/16
AK Scientific
Product number
J55553
Product name
Imidazo[1,2-a]pyrimidine
Packaging
1g
Price
$40
Updated
2021/12/16
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Imidazo[1,2-a]pyrimidine Chemical Properties,Usage,Production

Uses

Imidazo[1,2-a]pyrimidine is a heterocyclic aromatic compound used as a pharmaceutical intermediate ingredient, organic solvent and chemical reaction reagent. In the field of agrochemicals, it interacts with key enzymes such as acetylcholinesterase, lipoxygenase and glutathione-S-transferase. In the dye industry, it has been found to interact with a variety of proteins, including cytochrome P450 and peroxidase, making it an important component in dye formulations.

Synthesis

109-12-6

2032-35-1

274-95-3

In a 250-mL three-necked round-bottomed flask, 2-aminopyrimidine (5 g, 0.052 mol), bromoacetaldehyde diethyl acetal (20.7 g, 0.104 mol), 48% aqueous hydrobromic acid (5 mL), and ethanol (50 mL) were added sequentially. The reaction mixture was stirred at room temperature for 18 hours. After completion of the reaction, the reaction solution was cooled to room temperature. Subsequently, the reaction mixture was adsorbed onto silica gel and purified by column chromatography (eluent: dichloromethane/methanol), resulting in 5 g of imidazo[1,2-a]pyrimidine in about XX% yield.

References

[1] Patent: KR2017/126059, 2017, A. Location in patent: Paragraph 0069; 0072; 0073; 0076; 0077

Imidazo[1,2-a]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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Imidazo[1,2-a]pyrimidine Suppliers

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View Lastest Price from Imidazo[1,2-a]pyrimidine manufacturers

Henan Fengda Chemical Co., Ltd
Product
1,3a,7-triazaindene 274-95-3
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-02
Shanghai Rlavie Technology Co ltd
Product
Imidazo[1,2-a]pyrimidine 274-95-3
Price
US $0.00-0.00/kg
Min. Order
0.0001kg
Purity
98%min
Supply Ability
100kgs/month
Release date
2022-05-10
Honest Joy Holdings Limited
Product
Imidazo[1,2-a]pyrimidine 274-95-3
Price
US $0.00/KG
Min. Order
1KG
Purity
97.0%
Supply Ability
100 tons
Release date
2022-02-18

274-95-3, Imidazo[1,2-a]pyrimidineRelated Search:

Silver sulfadiazine Fluorocytosine Pyrimidine Levamisole Sulfadiazine Mebendazole Methimazole IMIDAZO[1,2-A]PYRIMIDINE-2-CARBOXYLIC ACID ETHYL ESTER IMIDAZO[1,2-A]PYRIDIN-8-YLAMINE Imidazo[1,2-a]pyridine-7-boronic acid pinacol ester METHYL IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLATE 6-(Hydroxymethyl)imidazo[1,2-a]pyridine 6-AMINO-IMIDAZO[1,2-A]PYRIMIDINE 3,N4-ETHENOCYTOSINE Imidazo[1,2-b]pyridazine-3-carboxaldehyde (9CI) Methyl imidazo[1,2-a]pyridine-5-carboxylate IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLIC ACID ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE

  • 1,8-Diazaindolizine
  • 1,3a,7-Triazaindene
  • IMIDAZO[1,2-A]PYRIMIDINE
  • Imidazo[1,2-a]pyrimidine&gt
  • Imidazo[1,2-a]pyrimidine (7CI, 8CI, 9CI, ACI)
  • Imidazolo [1,2-a] pyrimidine
  • 274-95-3
  • Fused Ring Systems
  • Pyrimidines
  • Heterocycle-Pyrimidine series
  • Fluorobenzene