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3-Amino-3-(3,4-dimethoxyphenyl)propionic acid

Product Name
3-Amino-3-(3,4-dimethoxyphenyl)propionic acid
CAS No.
34841-09-3
Chemical Name
3-Amino-3-(3,4-dimethoxyphenyl)propionic acid
Synonyms
ZERO/001614;BAS 01906516;Oprea1_306666;Oprea1_623871;573426_ALDRICH;AG-205/40088415;3-AMINO-3-(3 4-DIMETHOXYPHENYL)PROPIONI&;3-ammonio-3-(3,4-dimethoxyphenyl)propionate;3-ammonio-3-(3,4-dimethoxyphenyl)propanoate;3-azaniumyl-3-(3,4-dimethoxyphenyl)propanoate
CBNumber
CB9505023
Molecular Formula
C11H15NO4
Formula Weight
225.24
MOL File
34841-09-3.mol
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3-Amino-3-(3,4-dimethoxyphenyl)propionic acid Property

Melting point:
223 °C (dec.) (lit.)
Boiling point:
379.7±42.0 °C(Predicted)
Density 
1.212±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
powder to crystal
pka
3.73±0.10(Predicted)
color 
White to Almost white
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
573426
Product name
3-Amino-3-(3,4-dimethoxyphenyl)propionic acid
Purity
97%
Packaging
1g
Price
$56
Updated
2023/01/07
TCI Chemical
Product number
A2536
Product name
3-Amino-3-(3,4-dimethoxyphenyl)propionic Acid
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$32
Updated
2025/07/31
TCI Chemical
Product number
A2536
Product name
3-Amino-3-(3,4-dimethoxyphenyl)propionic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$157
Updated
2025/07/31
TRC
Product number
A597108
Product name
3-Amino-3-(3,4-dimethoxyphenyl)propanoicAcid
Packaging
100mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
X3123
Product name
3-Amino-3-(3,4-dimethoxyphenyl)propionic acid
Packaging
250mg
Price
$68
Updated
2021/12/16
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3-Amino-3-(3,4-dimethoxyphenyl)propionic acid Chemical Properties,Usage,Production

Synthesis

141-82-2

120-14-9

34840-85-2

3,4-dimethoxybenzaldehyde (50 g, 0.33 mol) and ammonium acetate (50 g) were mixed in 95% ethanol (50 ml). The mixture was heated to 50 °C, followed by slow addition of malonic acid (63 g, 0.6 mol) and supplemented with 95% ethanol (25 ml). The reaction mixture was refluxed for 3 hours and then the reaction was continued at 80°C for 24 hours. Upon completion of the reaction, the precipitate was collected by filtration, washed with ethanol and recrystallized in 50% ethanol to afford 47.8 g of the target product 3-amino-3-(3,4-dimethoxyphenyl)propionic acid as a white solid (yield: 65%). The product was characterized by 1H NMR (300 MHz, D2O): δ 6.90-6.87 (m, 3H), 4.44-4.39 (t, 1H), 3.69 (s, 3H), 3.67 (s, 3H), 2.76-2.57 (m, 2H). Mass spectrum (EI) m/z: 226 (M++H).

References

[1] Chemical Communications, 2011, vol. 47, # 20, p. 5894 - 5896
[2] Patent: WO2010/16939, 2010, A1. Location in patent: Page/Page column 57
[3] Synlett, 2013, vol. 24, # 6, p. 733 - 736
[4] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 11, p. 1207 - 1212
[5] Tetrahedron Asymmetry, 2008, vol. 19, # 17, p. 2072 - 2077

3-Amino-3-(3,4-dimethoxyphenyl)propionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Amino-3-(3,4-dimethoxyphenyl)propionic acid Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from 3-Amino-3-(3,4-dimethoxyphenyl)propionic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3-Amino-3-(3,4-dimethoxyphenyl)propanoic acid 34841-09-3
Price
US $1.10-9.90/KG
Min. Order
1KG
Purity
99%min
Supply Ability
100KG
Release date
2025-08-20
Shaanxi Dideu Medichem Co. Ltd
Product
3-Amino-3-(3,4-dimethoxyphenyl)propionic acid 34841-09-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-31
Career Henan Chemical Co
Product
3-Amino-3-(3,4-dimethoxyphenyl)propionic acid 34841-09-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-26

34841-09-3, 3-Amino-3-(3,4-dimethoxyphenyl)propionic acidRelated Search:


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  • 3-ammonio-3-(3,4-dimethoxyphenyl)propanoate
  • 3-ammonio-3-(3,4-dimethoxyphenyl)propionate
  • 3-azaniumyl-3-(3,4-dimethoxyphenyl)propanoate
  • 573426_ALDRICH
  • AG-205/40088415
  • BAS 01906516
  • Oprea1_306666
  • Oprea1_623871
  • Propanoic acid, 3-amino-3-(3,4-dimethoxyphenyl)-
  • ZERO/001614
  • 3-Amino-3-(3,4-dimethoxyphenyl)propionicAcid&gt
  • Benzenepropanoic acid, β-amino-3,4-dimethoxy-
  • 3-Amino-3-(3,4-dimethoxyphenyl)propionic Acid, ≥ 98.0%
  • 34841-09-3
  • H3CO2C6H3CHNH2CH2CO2H
  • API intermediates
  • C11 to C12
  • Carbonyl Compounds
  • Carboxylic Acids