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Dolutegravir Impurity C

Product Name
Dolutegravir Impurity C
CAS No.
1802141-49-6
Chemical Name
Dolutegravir Impurity C
Synonyms
Durutevir impurity 23;Dolutegravir Impurity 20;Dolutegravir Impurity 23;Dolutegravir Impurity 32;Syringaresinol Impurity 1(Syringaresinol Diglucoside);(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:;(4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber
CB96222324
Molecular Formula
C22H23F2N3O5
Formula Weight
447.43
MOL File
1802141-49-6.mol
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Dolutegravir Impurity C Property

Boiling point:
688.1±55.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
pka
10.71±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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Dolutegravir Impurity C Chemical Properties,Usage,Production

Uses

O-Ethyl Dolutegravir is an impurity of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity C Preparation Products And Raw materials

Raw materials

Preparation Products

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Dolutegravir Impurity C Suppliers

Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.
Tel
020-89854820
Email
sales@jzpharma.cn
Country
China
ProdList
1130
Advantage
58
Molcoo Chemicals Inc.
Tel
18576690171 17386083646
Email
3001006472@qq.com
Country
China
ProdList
11837
Advantage
58
Shenzhen Roark Pharma-Tec Co., Ltd.
Tel
13128912434
Email
2880126944@qq.com
Country
China
ProdList
2577
Advantage
58
HX Pharmaceutical technology co., LTD
Tel
15671363360
Email
494267389@qq.com
Country
China
ProdList
3630
Advantage
58
guoyungurui
Tel
18162595016; 18162595016
Email
3287908757@qq.com
Country
China
ProdList
10335
Advantage
58
ShenZhen H&D Pharmaceutical Technology Co., LTD
Tel
18126517264
Email
2850476883@qq.com
Country
China
ProdList
7864
Advantage
58
Hubei Moco Chemical Co., Ltd.
Tel
18627753421 18627756402
Fax
QQ:3001051413
Email
3001009495@qq.com
Country
China
ProdList
19063
Advantage
58

1802141-49-6, Dolutegravir Impurity CRelated Search:


  • Dolutegravir Impurity 20
  • (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:
  • Dolutegravir Impurity 23
  • (4R,12aS)-N-(2,4-difluorobenzyl)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1'',2'':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
  • 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-ethoxy-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-
  • Dolutegravir Impurity 32
  • Syringaresinol Impurity 1(Syringaresinol Diglucoside)
  • Durutevir impurity 23
  • 1802141-49-6