PIPERAZINE-2-CARBOXYLIC ACID

Application

Product Name: PIPERAZINE-2-CARBOXYLIC ACID
CAS No.: 133525-05-0
Chemical Name: PIPERAZINE-2-CARBOXYLIC ACID
Synonyms: TIMTEC-BB SBB004226;2-piperazinecarboxyli acid;piperazin-2-carboxylic acid;2-PIPERAZINECARBOXYLIC ACID;Piperazine-2-carboxylicacidHCl;R,S-PIPERAZINE-2-CARBOXYLIC ACID;piperazidine-2- carboxylic acid dihydrochloride;(+/-)-PIPERAZINE-2-CARBOXYLIC ACID HYDROCHLORIDE;(S)-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE 98%
CBNumber: CB9663394
Molecular Formula: C5H10N2O2.2ClH
Formula Weight: 203.07
MOL File: 133525-05-0.mol

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PIPERAZINE-2-CARBOXYLIC ACID Property

Melting point:: 265 °C (dec.)(lit.)
pka: pKa1 1.5,pKa2 5.41,pKa3 9.53（22℃）
CAS DataBase Reference: 133525-05-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
Hazard Note: Irritant

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 241279
Product name: Piperazine-2-carboxylic acid
Packaging: 1g
Price: $170
Updated: 2021/12/16

Chem-Impex

Product number: 14029
Product name: Piperazine-2-carboxylic acid
Purity: ≥ 99% (Assay by titration on dried basis)
Packaging: 25G
Price: $243
Updated: 2021/12/16

Chem-Impex

Product number: 14029
Product name: Piperazine-2-carboxylic acid
Purity: ≥ 99% (Assay by titration on dried basis)
Packaging: 1G
Price: $20.7
Updated: 2021/12/16

Chem-Impex

Product number: 14029
Product name: Piperazine-2-carboxylic acid
Purity: ≥ 99% (Assay by titration on dried basis)
Packaging: 5G
Price: $67.3
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM1031105
Product name: PIPERAZINE-2-CARBOXYLIC ACIDHYDROCHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $496.8
Updated: 2021/12/16

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PIPERAZINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Application

Piperazine-2-carboxylic acid dihydrochloride can be used as a pharmaceutical synthesis intermediate. The reaction proceeds as follows: Piperazine-2-carboxylic acid dihydrochloride (2 g, 9.8 mmol) and (Boc)₂O (8.6 g, 39.4 mmol) are dissolved in THF (40 mL) and water (40 mL). Sodium bicarbonate (8.31 g, 79.8 mmol) is added. The reaction mixture is magnetically stirred at room temperature for 4 hours, then ethyl acetate is added. The mixture is separated using a separatory funnel. The separated organic phase is washed with saturated brine, dried over anhydrous sodium sulfate, concentrated under reduced pressure, and then separated by silica gel column chromatography. 2.5 g of 1,4-di-tert-butoxycarbonylpiperazine-2-carboxylic acid (13-2) was obtained after purification, with a yield of 78%. LC-MS (ESI): m/z (M+1) 331.2.

PIPERAZINE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

2-Pyrazinecarboxylic acid Sodium chloride Palladium Hydrochloric acid Hydrogen Sodium hydroxide Sulfuric acid

Preparation Products

1-Boc-3-hydroxymethyl-piperazine

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PIPERAZINE-2-CARBOXYLIC ACID Suppliers

China 41 Europe 2 Germany 4 India 1 Slovakia 1 Switzerland 1 Ukraine 1 United Kingdom 6 United States 19 Global 76

Pure Chemistry Scientific Inc.

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BOC Sciences

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Country: United States
ProdList: 19552
Advantage: 58

Alchem Pharmtech,Inc.

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Country: United States
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Protheragen-ING

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Email: info@protheragen-ing.com
Country: United States
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United States Biological

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Matrix Scientific

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TimTec Corporation

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ChemPacific Corporation

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Sinova Inc.

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View Lastest Price from PIPERAZINE-2-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co

Product: PIPERAZINE-2-CARBOXYLIC ACID 133525-05-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-09

133525-05-0, PIPERAZINE-2-CARBOXYLIC ACIDRelated Search:

Piperazine-2-carboxylic acid dihydrochloride 1-(TERT-BUTOXYCARBONYL)-4-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-2-PIPERAZINECARBOXYLIC ACID Ethyl 1,4-dimethylpiperazine-2-carboxylate PIPERAZINE-2-CARBOXYLIC ACID Piperazine-2-carboxylic acid methyl ester dihydrochloride Ethyl 1,4-dibenzylpiperazine-2-carboxylate (R)-CPP 2-Piperazinecarboxylic acid dihydrochloride 2-PHENYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 2-ETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1-(2-CARBOXY-PHENYL)-PIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER 1-N-BOC-2-PIPERAZINECARBOXYLIC ACID METHYL ESTER (S)-1-Boc-3-methylpiperazine 1-Boc-4-(2-pyridinyl)-piperazine 2-PIPERAZINECARBOXYLIC ACID, (2R)- (R)-1-Boc-3-methylpiperazine 2-PIPERAZINECARBOXYLIC ACID, (2S)- 4-(6,7-Dimethoxyquinazolin-4-yl)-1-piperazinecarboxylic acid 2-hydroxy-2-methylpropyl ester

(+/-)-PIPERAZINE-2-CARBOXYLIC ACID HYDROCHLORIDE

R,S-PIPERAZINE-2-CARBOXYLIC ACID

TIMTEC-BB SBB004226

2-PIPERAZINECARBOXYLIC ACID

(S)-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE 98%

Piperazine-2-carboxylicacidHCl

2-piperazinecarboxyli acid

piperazin-2-carboxylic acid

piperazidine-2- carboxylic acid dihydrochloride

133525-05-0

89-97-5

C5H10N2O2HCl

C5H10N2O2

Building Blocks

Piperazines

Heterocyclic Building Blocks