(R)-1-Boc-3-methylpiperazine

Product Name: (R)-1-Boc-3-methylpiperazine
CAS No.: 163765-44-4
Chemical Name: (R)-1-Boc-3-methylpiperazine
Synonyms: tert-butyl (R)-3-methylpiperazine-1-carboxylate;(R)-4-N-BOC-2-METHYLPIPERAZINE;(R)-tert-butyl 3-Methylpiperazine-1-carboxylate;(R)-4-Boc-2-Methylpi;(R)-N-BOC-2-METHYLPIPERAZINE;(R)-1-BOC-3-METHYLPIPERAZINE;(R)-4-BOC-2-METHYLPIPERAZINE;(R)-N4-BOC-2-METHYLPIPERAZINE;(R)-3-Methyl-1-Boc-piperazine;(3R)-1-BOC-3-METHYLPIPERAZINE
CBNumber: CB4192376
Molecular Formula: C10H20N2O2
Formula Weight: 200.28
MOL File: 163765-44-4.mol

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(R)-1-Boc-3-methylpiperazine Property

Melting point:: 40-45 °C
Boiling point:: 268.7±15.0 °C(Predicted)
Density: 0.997±0.06 g/cm3(Predicted)
Flash point:: 223 °F
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 8.52±0.40(Predicted)
form: Crystalline Powder
color: White
optical activity: [α]/D +16±2°, c = 1 in dioxane
InChIKey: FMLPQHJYUZTHQS-MRVPVSSYSA-N
CAS DataBase Reference: 163765-44-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41-36/37/38
Safety Statements: 26-39-37/39
WGK Germany: 3
F: 10-34
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar

Product number: H27350
Product name: (R)-(+)-1-Boc-3-methylpiperazine, 97%
Packaging: 1g
Price: $69.65
Updated: 2024/03/01

Alfa Aesar

Product number: H27350
Product name: (R)-(+)-1-Boc-3-methylpiperazine, 97%
Packaging: 5g
Price: $212.65
Updated: 2024/03/01

Sigma-Aldrich

Product number: 674761
Product name: (R)-1-Boc-3-methylpiperazine
Purity: 97%
Packaging: 1g
Price: $90.7
Updated: 2024/03/01

TRC

Product number: B656835
Product name: (R)-4-Boc-2-methylpiperazine
Packaging: 10g
Price: $160
Updated: 2021/12/16

TRC

Product number: B656835
Product name: (R)-4-Boc-2-methylpiperazine
Packaging: 250g
Price: $1375
Updated: 2021/12/16

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(R)-1-Boc-3-methylpiperazine Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

(R)-4-Boc-2-methylpiperazine is a reagent used in organic synthesis. Used in the synthesis of orally bioavailable inhibitors of 11-β-hydroxysteroid. (R)-4-Boc-2-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

To a solution of (R)-methylpiperazine (400 mg) in dichloromethane (20 mL) at 0 ℃ was added di-tert-butyl dicarbonate (871 mg). The reaction was stirred at room temperature for 4 h and then quenched with water (20 mL), followed by extraction into dichloromethane (2 x 40 mL). The combined organics were washed with saturated aqueous brine solution (40 mL), dried (MgSO4), and concentrated to give (R)-1-Boc-3-methylpiperazine as a white solid (669 mg, 84%).

(R)-1-Boc-3-methylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-1-Boc-3-methylpiperazine Suppliers

China 219 Europe 2 France 1 Germany 4 India 2 Japan 1 Switzerland 1 United Kingdom 11 United States 44 Global 285

J & K SCIENTIFIC LTD.

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View Lastest Price from (R)-1-Boc-3-methylpiperazine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (R)-4-Boc-2-methylpiperazine 163765-44-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-17

Shanghai UCHEM Inc.

Product: (R)-4-Boc-2-methylpiperazine 163765-44-4
Price: US $37.00-788.00/g
Min. Order: 10g
Purity: 0.99
Supply Ability: 25kg
Release date: 2023-12-18

Honest Joy Holdings Limited

Product: (R)-4-N-Boc-2-methylpiperazine 163765-44-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.3%
Supply Ability: 100 tons
Release date: 2022-02-08

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(R)-4-N-Boc-2-methylpiperazine (R )-4-N-Boc-2-methyl piperazine

(R)-2-Methylpiperazine, N4-BOC protected

(R)-1-Boc-3-methylpiperazine, tert-Butyl (R)-3-methyl-1-piperazinecarboxylate

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(R)-4-Boc-2-Methylpi

(<i>R</i>)-(+)-1-Boc-3-Methylpiperazine

(R)-4-N-Boc-2-Methyl-piperazine/(R)-1-Boc-3-Methylpiperazine

(R)-butyl 3-Methylpiperazine-1-carboxylate

(R)-(+)-1-Boc-3-methylpiperazine,97%

tert-butyl (R)-3-methylpiperazine-1-carboxylate

tert-Butyl (3R)-3-methylpiperazine-1-carboxylate, (3R)-1-(tert-Butoxycarbonyl)-3-methylpiperazine

1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3R)- (9CI, ACI)

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(R)-tert-butyl-2- methylpiperazine-4-carboxylate

163765-44-4

345-75-7

C10H20N2O2

Chiral Building Blocks

Asymmetric Synthesis

Heterocyclic Building Blocks

Piperazines

Piperaizine

Piperazine series

pharmacetical