ChemicalBook > CAS DataBase List > (S)-1-Boc-3-methylpiperazine

(S)-1-Boc-3-methylpiperazine

Product Name
(S)-1-Boc-3-methylpiperazine
CAS No.
147081-29-6
Chemical Name
(S)-1-Boc-3-methylpiperazine
Synonyms
tert-butyl (S)-3-methylpiperazine-1-carboxylate;(S)-1-BOC-3-METHYLPIPERAZINE;(S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-4-Boc-2-methylpiperazine;4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID;4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid;CPD2809-SM;(3S)-3-MethyL;(S)-4-N-BOC-2-METHYL;Sotorasib Impurity 2
CBNumber
CB9458934
Molecular Formula
C10H20N2O2
Formula Weight
200.28
MOL File
147081-29-6.mol
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(S)-1-Boc-3-methylpiperazine Property

Melting point:
40-45 °C
alpha 
-16 º (c=1 in dioxane)
Boiling point:
268.7±15.0 °C(Predicted)
Density 
0.997±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
form 
Crystalline Powder
pka
8.52±0.40(Predicted)
color 
White to yellow
optical activity
[α]/D -16±2°, c = 1 in dioxane
Sensitive 
Air Sensitive
InChI
InChI=1S/C10H20N2O2/c1-8-7-12(6-5-11-8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1
InChIKey
FMLPQHJYUZTHQS-QMMMGPOBSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCN[C@@H](C)C1
CAS DataBase Reference
147081-29-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41-34
Safety Statements 
26-39-45-36/37/39
RIDADR 
3259
WGK Germany 
3
10-34
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
63207
Product name
(S)-1-Boc-3-methylpiperazine
Purity
≥98%
Packaging
1g
Price
$21.9
Updated
2024/03/01
Sigma-Aldrich
Product number
63207
Product name
(S)-1-Boc-3-methylpiperazine
Purity
≥98%
Packaging
5G
Price
$65.4
Updated
2024/03/01
Alfa Aesar
Product number
H27534
Product name
(S)-(-)-1-Boc-3-methylpiperazine, 98%
Packaging
1g
Price
$64.65
Updated
2024/03/01
Alfa Aesar
Product number
H27534
Product name
(S)-(-)-1-Boc-3-methylpiperazine, 98%
Packaging
5g
Price
$256
Updated
2024/03/01
TRC
Product number
B656830
Product name
(S)-4-Boc-2-methylpiperazine
Packaging
25g
Price
$305
Updated
2021/12/16
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(S)-1-Boc-3-methylpiperazine Chemical Properties,Usage,Production

Description

(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. This compound also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.

Chemical Properties

colorless to yellow liquid

Uses

Laboratory chemicals, Manufacture of substances.

Uses

Reactant involved in the synthesis of biologically activy molecules including:

  • CCR5 antagonists with anti-HIV-1 activity
  • Opioid receptor antagonists
  • Human growth hormone secretagogue receptor antagonists for treatment of obesity
  • Fatty acid oxidation inhibitors

Uses

(S)-4-Boc-2-methylpiperazine ((S)-1-Boc-3-methylpiperazine) is a reagent used in the synthesis of benzamide peptidomimetic as non-ATP competitive inihbitors.

(S)-1-Boc-3-methylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-1-Boc-3-methylpiperazine Suppliers

Chengdu Firster Pharmaceutical Co., Ltd.
Tel
028-87078428 028-87074958
Fax
8772-8116
Email
chengzhenyong@cdfirster.com
Country
China
ProdList
1989
Advantage
60
SanoChem (Chengdu) Tech. Co., Ltd.
Tel
28-87999436 02887999436
Fax
QQ:2746983436
Email
sales@sano-chem.com
Country
China
ProdList
3929
Advantage
55
Changzhou Huanling Chemical Co., Ltd.
Tel
0519-89803565 13776850645
Fax
0519-89803575
Email
info@huanlingchem.com
Country
China
ProdList
640
Advantage
68
Shanghai Synteam Biochem CO.,ltd
Tel
+86-021-58380978 +86-18017016373
Fax
021-58380978
Email
info@systeambc.com
Country
China
ProdList
936
Advantage
50
AstaTech(Chengdu) Biopharmaceutical Corp.
Tel
028-82666846 18080826311
Fax
QQ 2917178106
Email
sales@astatech.com.cn
Country
China
ProdList
545
Advantage
58
Purest Pharmaceuticl (Xi’an) Co,.LTD
Tel
+86-13893405577 +86-13522261260
Email
12829054@qq.com
Country
China
ProdList
72
Advantage
58
Shanghai Youna Biopharmaceutical Co., Ltd
Tel
18164002430
Email
1930759283@qq.com
Country
China
ProdList
223
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
400-0255188 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5268
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
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View Lastest Price from (S)-1-Boc-3-methylpiperazine manufacturers

Shanghai UCHEM Inc.
Product
(S)-4-N-Boc-2-methylpiperazine 147081-29-6
Price
US $37.00-788.00/g
Min. Order
10g
Purity
0.99
Supply Ability
25kg
Release date
2023-12-15
Hebei Mingeng Biotechnology Co., Ltd
Product
(S)-4-N-Boc-2-methylpiperazine 147081-29-6
Price
US $150.00/ASSAYS
Min. Order
10g
Purity
>99%
Supply Ability
500kg/month
Release date
2021-12-23
LY Global chemicals co.,ltd .
Product
(S)-4-N-Boc-2-methylpiperazine 147081-29-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2023-03-27

147081-29-6, (S)-1-Boc-3-methylpiperazineRelated Search:


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  • Sotorasib Impurity 2
  • 147081-29-6
  • Asymmetric Synthesis
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  • pharmacetical
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  • 147081-29-6