(S)-1-Boc-3-methylpiperazine

Product Name: (S)-1-Boc-3-methylpiperazine
CAS No.: 147081-29-6
Chemical Name: (S)-1-Boc-3-methylpiperazine
Synonyms: tert-butyl (S)-3-methylpiperazine-1-carboxylate;(S)-1-BOC-3-METHYLPIPERAZINE;(S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-4-Boc-2-methylpiperazine;4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID;4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid;CPD2809-SM;(3S)-3-MethyL;(S)-4-N-BOC-2-METHYL;Sotorasib Impurity 2
CBNumber: CB9458934
Molecular Formula: C10H20N2O2
Formula Weight: 200.28
MOL File: 147081-29-6.mol

More

Less

(S)-1-Boc-3-methylpiperazine Property

Melting point:: 40-45 °C
alpha: -16 º (c=1 in dioxane)
Boiling point:: 268.7±15.0 °C(Predicted)
Density: 0.997±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
form: Crystalline Powder
pka: 8.52±0.40(Predicted)
color: White to yellow
optical activity: [α]/D -16±2°, c = 1 in dioxane
Sensitive: Air Sensitive
InChI: InChI=1S/C10H20N2O2/c1-8-7-12(6-5-11-8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1
InChIKey: FMLPQHJYUZTHQS-QMMMGPOBSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCN[C@@H](C)C1
CAS DataBase Reference: 147081-29-6(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 37/38-41-34
Safety Statements: 26-39-45-36/37/39
RIDADR: 3259
WGK Germany: 3
F: 10-34
HS Code: 29335990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 63207
Product name: (S)-1-Boc-3-methylpiperazine
Purity: ≥98%
Packaging: 1g
Price: $21.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 63207
Product name: (S)-1-Boc-3-methylpiperazine
Purity: ≥98%
Packaging: 5G
Price: $65.4
Updated: 2024/03/01

Alfa Aesar

Product number: H27534
Product name: (S)-(-)-1-Boc-3-methylpiperazine, 98%
Packaging: 1g
Price: $64.65
Updated: 2024/03/01

Alfa Aesar

Product number: H27534
Product name: (S)-(-)-1-Boc-3-methylpiperazine, 98%
Packaging: 5g
Price: $256
Updated: 2024/03/01

TRC

Product number: B656830
Product name: (S)-4-Boc-2-methylpiperazine
Packaging: 25g
Price: $305
Updated: 2021/12/16

More

Less

(S)-1-Boc-3-methylpiperazine Chemical Properties,Usage,Production

Description

(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. This compound also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.

Chemical Properties

colorless to yellow liquid

Uses

Laboratory chemicals, Manufacture of substances.

Uses

Reactant involved in the synthesis of biologically activy molecules including:

CCR5 antagonists with anti-HIV-1 activity
Opioid receptor antagonists
Human growth hormone secretagogue receptor antagonists for treatment of obesity
Fatty acid oxidation inhibitors

Uses

(S)-4-Boc-2-methylpiperazine ((S)-1-Boc-3-methylpiperazine) is a reagent used in the synthesis of benzamide peptidomimetic as non-ATP competitive inihbitors.

(S)-1-Boc-3-methylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(S)-1-Boc-3-methylpiperazine Suppliers

Canada 1 China 270 Europe 2 France 2 Germany 3 India 7 Japan 1 Switzerland 1 United Kingdom 13 United States 51 Global 351

Chengdu Zhongde Jihua Pharmaceutical Technology Co., Ltd

Tel: 15928014948
Email: 3438599507@qq.com
Country: China
ProdList: 90
Advantage: 58

Chengdu Firster Pharmaceutical Co., Ltd.

Tel: 028-87078428 028-87074958
Fax: 8772-8116
Email: chengzhenyong@cdfirster.com
Country: China
ProdList: 2677
Advantage: 60

SanoChem (Chengdu) Tech. Co., Ltd.

Tel: 28-87999436 02887999436
Fax: QQ:2746983436
Email: sales@sano-chem.com
Country: China
ProdList: 3795
Advantage: 55

Shanghai Synteam Biochem CO.,ltd

Tel: +86-021-58380978 +86-18017016373
Fax: 021-58380978
Email: info@systeambc.com
Country: China
ProdList: 948
Advantage: 50

AstaTech(Chengdu) Biopharmaceutical Corp.

Tel: 028-82666846 18080826311
Fax: QQ 2917178106
Email: sales@astatech.com.cn
Country: China
ProdList: 499
Advantage: 58

Purest Pharmaceuticl （Xi’an) Co,.LTD

Tel: +86-13893405577 +86-13522261260
Email: 12829054@qq.com
Country: China
ProdList: 72
Advantage: 58

Shanghai Youna Biopharmaceutical Co., Ltd

Tel: 18164002430
Email: 511710754@qq.com
Country: China
ProdList: 228
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

More

Less

View Lastest Price from (S)-1-Boc-3-methylpiperazine manufacturers

Shanghai UCHEM Inc.

Product: (S)-4-N-Boc-2-methylpiperazine 147081-29-6
Price: US $37.00-788.00/g
Min. Order: 10g
Purity: 0.99
Supply Ability: 25kg
Release date: 2023-12-15

AstaTech(Chengdu) Biopharmaceutical Corp.

Product: (S)-4-N-Boc-2-methylpiperazine 147081-29-6
Price: US $0.00-0.00/KG
Min. Order: 0.5KG
Purity: 99.0%GC
Supply Ability: 1-5tons/year
Release date: 2022-01-07

Henan Fengda Chemical Co., Ltd

Product: (S)-1-Boc-3-methylpiperazine 147081-29-6
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-15

147081-29-6, (S)-1-Boc-3-methylpiperazineRelated Search:

(S)-1-Boc-3-benzylpiperazine (S)-tert-butyl 3-formylpiperidine-1-carboxylate (3S)-3-AMinoazepane-1-carboxylic Acid tert-Butyl Ester (S)-1-N-Boc-3-ethylpiperazine (S)-1-BOC-3-PROPYLPIPERAZINE R-N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid N-4-Boc-2-piperazinecarboxylic acid (S)-1-Boc-3-methylpiperazine 1-BOC-3,5-DIMETHYL-PIPERAZINE t-Butyl(2R,5S)-2,5-dimethylpiperazine-1-carboxylate (R)-4-N-Boc-piperazine-2-carboxylic acid methyl ester (R)-1-BOC-3-(Hydroxymethyl)piperazine (S)-2-tert-Butylcarboxamide-4-tert-butoxycarbonyl piperazine (1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE (S)-1-N-Boc-2-methylpiperazine 4-N-Boc-2-Methyl-piperazine 1-Boc-2-Methylpiperazine (R)-1-Boc-3-methylpiperazine

TERT-BUTYL (S)-3-METHYL-1-PIPERAZINECARBOXYLATE

(S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE

(S)-N4-BOC-2-METHYLPIPERAZINE

(S)-1-TERT-BUTOXYCARBONYL-3-METHYLPIPERAZINE

(S)-1-N-BOC-3-METHYLPIPERAZINE

(S)-3-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(S)-1-BOC-3-METHYLPIPERAZINE

(S)-4-N-BOC-2-METHYL PIPERAZINE

1-PIPERAZINECARBOXYLIC ACID, 3-METHYL-, 1,1-DIMETHYLETHYL ESTER, (3S)-

tert-butyl (S)-3-methylpiperazine-1-carboxylate

(S)-1-Boc-3-methylpiperazine≥ 99% (HPLC, Chiral purity)

4-BOC-2-(S)-METHYL-PIPERAZINE

(3S)-1-BOC-3-METHYLPIPERAZINE

(S)-3-Methyl-1-Boc-piperazine

(S)-4-N-Boc-2-MethylPiperazinee

4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID

(S)-4-N-Boc-2-methylpiperazine (S)-4-N-Boc-2-methyl piperazine

(S)-2-METHYL-1-BOC-PIPERAZINE

(S)-4-Boc-2-methylpiperazine

(S)-2-Methylpiperazine, N4-BOC protected

(S)-3-Methylpiperazine, N1-BOC protected

4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid

(S)-4-N-BOC-2-METHYL

(s)-3-methyl-piperazine-1-carboxylic acid tert-butyl

(S)-4-N-BOC-2-Methylpiperazine-HCl

(3S)-3-Methylpiperazine-1-carboxylic acid tert-butyl ester

tert-Butyl (3S)-3-methylpiperazine-1-carboxylate, (3S)-1-(tert-Butoxycarbonyl)-3-methylpiperazine

(S)-1-Boc-3-Methylpiperazine

(S)-1-Boc-3-Methylpiperazine, 98%+

(3S)-3-Methylpiperazine, N1-BOC protected

Chemdraw8(S)-3-Methyl-piperazine-1-carboxylic acid tert-butyl ester

CPD2809-SM

(3S)-3-MethyL

(S)-4-N-Boc-2-methylpiperazine ISO 9001：2015 REACH

1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3S)- (9CI, ACI)

3-methyl-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester (3S)- (9CI ACI)

3-Methyl-1-piperazinecarboxylic acid tert-butyl ester (3S)-

Sotorasib Impurity 2

147081-29-6

Asymmetric Synthesis

Chiral Building Blocks

Heterocyclic Building Blocks

Piperazines

pharmacetical

Piperazine series

Quinoline series

Piperaizine

147081-29-6