(S)-1-Boc-3-methylpiperazine

Product Name: (S)-1-Boc-3-methylpiperazine
CAS No.: 147081-29-6
Chemical Name: (S)-1-Boc-3-methylpiperazine
Synonyms: tert-butyl (S)-3-methylpiperazine-1-carboxylate;(S)-1-BOC-3-METHYLPIPERAZINE;(S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-4-Boc-2-methylpiperazine;4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID;4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid;CPD2809-SM;(3S)-3-MethyL;(S)-4-N-BOC-2-METHYL;Sotorasib Impurity 2
CBNumber: CB9458934
Molecular Formula: C10H20N2O2
Formula Weight: 200.28
MOL File: 147081-29-6.mol

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(S)-1-Boc-3-methylpiperazine Property

Melting point:: 40-45 °C
alpha: -16 º (c=1 in dioxane)
Boiling point:: 268.7±15.0 °C(Predicted)
Density: 0.997±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
form: Crystalline Powder
pka: 8.52±0.40(Predicted)
color: White to yellow
optical activity: [α]/D -16±2°, c = 1 in dioxane
Sensitive: Air Sensitive
InChI: InChI=1S/C10H20N2O2/c1-8-7-12(6-5-11-8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1
InChIKey: FMLPQHJYUZTHQS-QMMMGPOBSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCN[C@@H](C)C1
CAS DataBase Reference: 147081-29-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41-34
Safety Statements: 26-39-45-36/37/39
RIDADR: 3259
WGK Germany: 3
F: 10-34
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 63207
Product name: (S)-1-Boc-3-methylpiperazine
Purity: ≥98%
Packaging: 1g
Price: $21.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 63207
Product name: (S)-1-Boc-3-methylpiperazine
Purity: ≥98%
Packaging: 5G
Price: $65.4
Updated: 2024/03/01

Alfa Aesar

Product number: H27534
Product name: (S)-(-)-1-Boc-3-methylpiperazine, 98%
Packaging: 1g
Price: $64.65
Updated: 2024/03/01

Alfa Aesar

Product number: H27534
Product name: (S)-(-)-1-Boc-3-methylpiperazine, 98%
Packaging: 5g
Price: $256
Updated: 2024/03/01

TRC

Product number: B656830
Product name: (S)-4-Boc-2-methylpiperazine
Packaging: 25g
Price: $305
Updated: 2021/12/16

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(S)-1-Boc-3-methylpiperazine Chemical Properties,Usage,Production

Description

(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. This compound also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.

Chemical Properties

colorless to yellow liquid

Uses

Laboratory chemicals, Manufacture of substances.

Uses

Reactant involved in the synthesis of biologically activy molecules including:

CCR5 antagonists with anti-HIV-1 activity
Opioid receptor antagonists
Human growth hormone secretagogue receptor antagonists for treatment of obesity
Fatty acid oxidation inhibitors

Uses

(S)-4-Boc-2-methylpiperazine ((S)-1-Boc-3-methylpiperazine) is a reagent used in the synthesis of benzamide peptidomimetic as non-ATP competitive inihbitors.

(S)-1-Boc-3-methylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-1-Boc-3-methylpiperazine Suppliers

Canada 1 China 269 Europe 2 France 2 Germany 3 India 7 Japan 1 Switzerland 1 United Kingdom 13 United States 51 Global 350

Alfa Aesar

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KVB Asta Life Sciences India Pvt. ltd.

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Clearsynth Labs

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Reax Chemicals

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Avra Synthesis Pvt Ltd

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A.J Chemicals

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Email: sales@ajchem.in
Country: India
ProdList: 6100
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View Lastest Price from (S)-1-Boc-3-methylpiperazine manufacturers

Shanghai UCHEM Inc.

Product: (S)-4-N-Boc-2-methylpiperazine 147081-29-6
Price: US $37.00-788.00/g
Min. Order: 10g
Purity: 0.99
Supply Ability: 25kg
Release date: 2023-12-15

AstaTech(Chengdu) Biopharmaceutical Corp.

Product: (S)-4-N-Boc-2-methylpiperazine 147081-29-6
Price: US $0.00-0.00/KG
Min. Order: 0.5KG
Purity: 99.0%GC
Supply Ability: 1-5tons/year
Release date: 2022-01-07

Henan Fengda Chemical Co., Ltd

Product: (S)-1-Boc-3-methylpiperazine 147081-29-6
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-15

147081-29-6, (S)-1-Boc-3-methylpiperazineRelated Search:

(S)-1-Boc-3-benzylpiperazine (S)-tert-butyl 3-formylpiperidine-1-carboxylate (3S)-3-AMinoazepane-1-carboxylic Acid tert-Butyl Ester (S)-1-N-Boc-3-ethylpiperazine (S)-1-BOC-3-PROPYLPIPERAZINE R-N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid N-4-Boc-2-piperazinecarboxylic acid (S)-1-Boc-3-methylpiperazine 1-BOC-3,5-DIMETHYL-PIPERAZINE t-Butyl(2R,5S)-2,5-dimethylpiperazine-1-carboxylate (R)-4-N-Boc-piperazine-2-carboxylic acid methyl ester (R)-1-BOC-3-(Hydroxymethyl)piperazine (S)-2-tert-Butylcarboxamide-4-tert-butoxycarbonyl piperazine (1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE (S)-1-N-Boc-2-methylpiperazine 4-N-Boc-2-Methyl-piperazine 1-Boc-2-Methylpiperazine (R)-1-Boc-3-methylpiperazine

TERT-BUTYL (S)-3-METHYL-1-PIPERAZINECARBOXYLATE

(S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE

(S)-N4-BOC-2-METHYLPIPERAZINE

(S)-1-TERT-BUTOXYCARBONYL-3-METHYLPIPERAZINE

(S)-1-N-BOC-3-METHYLPIPERAZINE

(S)-3-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(S)-1-BOC-3-METHYLPIPERAZINE

(S)-4-N-BOC-2-METHYL PIPERAZINE

1-PIPERAZINECARBOXYLIC ACID, 3-METHYL-, 1,1-DIMETHYLETHYL ESTER, (3S)-

tert-butyl (S)-3-methylpiperazine-1-carboxylate

(S)-1-Boc-3-methylpiperazine≥ 99% (HPLC, Chiral purity)

4-BOC-2-(S)-METHYL-PIPERAZINE

(3S)-1-BOC-3-METHYLPIPERAZINE

(S)-3-Methyl-1-Boc-piperazine

(S)-4-N-Boc-2-MethylPiperazinee

4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID

(S)-4-N-Boc-2-methylpiperazine (S)-4-N-Boc-2-methyl piperazine

(S)-2-METHYL-1-BOC-PIPERAZINE

(S)-4-Boc-2-methylpiperazine

(S)-2-Methylpiperazine, N4-BOC protected

(S)-3-Methylpiperazine, N1-BOC protected

4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid

(S)-4-N-BOC-2-METHYL

(s)-3-methyl-piperazine-1-carboxylic acid tert-butyl

(S)-4-N-BOC-2-Methylpiperazine-HCl

(3S)-3-Methylpiperazine-1-carboxylic acid tert-butyl ester

tert-Butyl (3S)-3-methylpiperazine-1-carboxylate, (3S)-1-(tert-Butoxycarbonyl)-3-methylpiperazine

(S)-1-Boc-3-Methylpiperazine

(S)-1-Boc-3-Methylpiperazine, 98%+

(3S)-3-Methylpiperazine, N1-BOC protected

Chemdraw8(S)-3-Methyl-piperazine-1-carboxylic acid tert-butyl ester

CPD2809-SM

(3S)-3-MethyL

(S)-4-N-Boc-2-methylpiperazine ISO 9001：2015 REACH

1-Piperazinecarboxylic acid, 3-methyl-, 1,1-dimethylethyl ester, (3S)- (9CI, ACI)

3-methyl-1-Piperazinecarboxylic acid 1,1-dimethylethyl ester (3S)- (9CI ACI)

3-Methyl-1-piperazinecarboxylic acid tert-butyl ester (3S)-

Sotorasib Impurity 2

147081-29-6

Asymmetric Synthesis

Chiral Building Blocks

Heterocyclic Building Blocks

Piperazines

pharmacetical

Piperazine series

Quinoline series

Piperaizine

147081-29-6