(S)-1-N-Boc-2-methylpiperazine

Product Name: (S)-1-N-Boc-2-methylpiperazine
CAS No.: 169447-70-5
Chemical Name: (S)-1-N-Boc-2-methylpiperazine
Synonyms: tert-butyl (S)-2-methylpiperazine-1-carboxylate;(R)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-1-Boc-2-methl-piperazine;(S)-N-Boc-2-methylpiperazine;(R)-2-METHYL-1-BOC-PIPERAZINE;1-Boc-2-(S)-Methyl Piperazine;(S)-1-Boc-2-methyl-piperazine;(S)-N1-BOC-2-METHYLPIPERAZINE;(S)-1-N-BOC-2-METHYL PIPERAZINE
CBNumber: CB9714476
Molecular Formula: C10H20N2O2
Formula Weight: 200.28
MOL File: 169447-70-5.mol

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(S)-1-N-Boc-2-methylpiperazine Property

Melting point:: 43.0 to 47.0 °C
Boiling point:: 268.7±15.0 °C(Predicted)
Density: 0.997±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 8.49±0.40(Predicted)
color: White to Almost white
InChI: InChI=1S/C10H20N2O2/c1-8-7-11-5-6-12(8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1
InChIKey: DATRVIMZZZVHMP-QMMMGPOBSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCNC[C@@H]1C
CAS DataBase Reference: 169447-70-5(CAS DataBase Reference)

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Safety

RIDADR: UN3077
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4846
Product name: (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $65
Updated: 2024/03/01

TCI Chemical

Product number: B4846
Product name: (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $258
Updated: 2024/03/01

TRC

Product number: B656975
Product name: (S)-1-Boc-2-methylpiperazine
Packaging: 10g
Price: $970
Updated: 2021/12/16

Activate Scientific

Product number: AS3110
Product name: (S)-1-Boc-2-methylpiperazine
Purity: 97+% ee
Packaging: 250g
Price: $1480
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0040694
Product name: (S)-1-N-BOC-2-METHYLPIPERAZINE
Purity: 95.00%
Packaging: 10G
Price: $2055.9
Updated: 2021/12/16

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(S)-1-N-Boc-2-methylpiperazine Chemical Properties,Usage,Production

Uses

(S)-1-N-Boc-2-methylpiperazine is used in the preparation of pyrazolo[3,4-b]pyridine dual pharmacophores as PDE4-muscarinic antagonists.

Synthesis

A solution of (S)-2-methyl piperazine (2 g, 20 mmol) in THF (200 ml_) was mixed with nBuLi (25 ml, 1.6 M in hexanes, 40 mmol) at rt. The solution was stirred for 30 minutes before TBDMSCI (3.04 g, 20 mmol) was added. The mixture was stirred for 1 hour and then (Boc)2O (5.2 g, 24 mmol) was added to the solution. After 1 hour, the solution was diluted with H2O (50 ml). The organic layer was separated, washed with brine (50 mL), dried over Na2SO4, and concentrated EPO under vacuum. Finally, (S)-1-N-Boc-2-methylpiperazine was obtained after purification.

(S)-1-N-Boc-2-methylpiperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-1-N-Boc-2-methylpiperazine Suppliers

Americas 1 Canada 1 China 191 Europe 3 Germany 3 India 3 Japan 2 United Kingdom 13 United States 38 Global 255

Shanghai Boc Chemical Co.,Ltd

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View Lastest Price from (S)-1-N-Boc-2-methylpiperazine manufacturers

Shanghai UCHEM Inc.

Product: (S)-1-N-Boc-2-methylpiperazine 169447-70-5
Price: US $73.00-607.00/g
Min. Order: 25g
Purity: 0.99
Supply Ability: 10
Release date: 2023-12-18

Career Henan Chemical Co

Product: (S)-1-N-Boc-2-methylpiperazine 169447-70-5
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-08-08

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(R)-2-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(R)-2-METHYL-1-BOC-PIPERAZINE

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(R)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE

(S)-1-Boc-2-methyl-piperazine

Tert-Butyl2(S)-methylpiperazine-1-carboxylate

2-S-Methyl-piperazine-1-carboxylic acid tert-butyl ester

(S)-1-N-Boc-2-Methylpiperizine tert-butyl 2(S)-methylpiperazine-1-carboxylate

(S)-N1-BOC-2-METHYLPIPERAZINE

(S)-1-Boc-2-methl-piperazine

(S)-1-N-Boc-2-Methylpiperazine ,98%

(2S)-2-Methylpiperazine, N1-BOC protected 98%

tert-Butyl (2S)-2-methylpiperazine-1-carboxylate (2S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine

(2S)-2-Methyl-1-piperazinecarboxylic Acid 1,1-DiMethylethyl Ester

tert-Butyl (2S)-2-Methylpiperazine-1-carboxylate

1-Piperazinecarboxylic acid, 2-methyl-, 1,1-dimethylethyl ester, (2S)-

(S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine

tert-butyl (S)-2-methylpiperazine-1-carboxylate

(2S)-2-Methylpiperazine,N1-BOCprotected98%

(S)-N-Boc-2-methylpiperazine

(S)-N-Boc-2-methylpiperazine,98%e.e.

(<i>S</i>)-1-(<i>tert</i>-Butoxycarbonyl)-2-methylpiperazine

(S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine &gt

(S)-2-Methyl-1-piperazinecarboxylic Acid tert-Butyl Ester

tert-Butyl (S)-2-Methyl-1-piperazinecarboxylate

169447-70-5

170033-47-4

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