1-Boc-2-Methylpiperazine

Product Name: 1-Boc-2-Methylpiperazine
CAS No.: 120737-78-2
Chemical Name: 1-Boc-2-Methylpiperazine
Synonyms: 1-Boc-2-Methylpiperazine;N-Boc-2-methylpiperazine;1-N-BOC-2-METHYLPIPERAZINE;N-4-BOC-3-METHYLPIPERIZINE;N-1-BOC-2-METHYLPIPERAZINE;4-N-Boc-3-methylpiperazine;4-Boc-3-Methyl piperazine;N-4-BOC-3-METHYL-PIPERAZINE;1-N-Boc-2-methyl-piperizine;(+/-)-1-N-BOC-2-METHYL PIPERAZINE
CBNumber: CB4391948
Molecular Formula: C10H20N2O2
Formula Weight: 200.28
MOL File: 120737-78-2.mol

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1-Boc-2-Methylpiperazine Property

Boiling point:: 268.7±15.0 °C(Predicted)
Density: 0.997±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Oil
pka: 8.49±0.40(Predicted)
color: Colourless
CAS DataBase Reference: 120737-78-2(CAS DataBase Reference)

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Safety

RIDADR: 2735
HazardClass: IRRITANT
PackingGroup: Ⅲ
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B6870
Product name: tert-Butyl 2-Methylpiperazine-1-carboxylate
Purity: min. 98.0 %
Packaging: 5G
Price: $94
Updated: 2025/07/31

TCI Chemical

Product number: B6870
Product name: tert-Butyl 2-Methylpiperazine-1-carboxylate
Purity: min. 98.0 %
Packaging: 25G
Price: $282
Updated: 2025/07/31

Usbiological

Product number: 262029
Product name: 1-Boc-2-methylpiperazine
Packaging: 1g
Price: $375
Updated: 2021/12/16

TRC

Product number: B809478
Product name: tert-Butyl2-Methylpiperazine-1-carboxylate
Packaging: 5mg
Price: $55
Updated: 2021/12/16

Oakwood

Product number: 037090
Product name: 1-N-Boc-2-methylpiperazine
Purity: 95%
Packaging: 5g
Price: $40
Updated: 2021/12/16

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1-Boc-2-Methylpiperazine Chemical Properties,Usage,Production

Uses

tert-Butyl 2-methylpiperazine-1-carboxylate is a useful reagent used in the synthesis of anthrafuran carboxamides with antitumor properties.

Synthesis

120737-77-1

120737-78-2

General procedure for the synthesis of tert-butyl 2-methylpiperazine-1-carboxylate from the compound (CAS: 120737-77-1): a mixture of tert-butyl (RS)-4-benzyl-2-methylpiperazine-1-carboxylate (3.41 g, 11.7 mmol), ethanol (125 mL), and Pearlman's catalyst (0.854 g, 6.08 mmol) was was hydrogenated overnight at 36 psi pressure at ambient temperature. Upon completion of the reaction, the mixture was filtered and the solids were washed sequentially with ethanol, dichloromethane (DCM) and methanol (MeOH). The filtrate and washings were combined, concentrated in vacuum, redissolved in dichloromethane, filtered again and concentrated in vacuum to give tert-butyl 2-methylpiperazine-1-carboxylate as a beige oil (2.0 g, 86% yield). The nuclear magnetic resonance (NMR) spectrum of the product was in agreement with the data reported in the literature (J. Org. Chem. 1995, 60, 4183).

References

[1] Patent: WO2007/135427, 2007, A1. Location in patent: Page/Page column 31
[2] Patent: US4880808, 1989, A

1-Boc-2-Methylpiperazine Preparation Products And Raw materials

Raw materials

1,1'-Carbonyldiimidazole Di-tert-butyl dicarbonate Trifluoroacetic acid N-Benzylethanolamine Diethyl azodicarboxylate Tetrahydrofuran Lithium Aluminum Hydride Dichloromethane Triphenylphosphine DL-Alanine

Preparation Products

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1-Boc-2-Methylpiperazine Suppliers

China 130 Germany 2 India 2 United Kingdom 10 United States 30 Global 174

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
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J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
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Fax: 86-027-87531808
Email: sales@chemwish.com
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Capot Chemical Co., Ltd

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Sichuan Guanghan Bio-Tech Co., Ltd

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Jia Xing Isenchem Co.,Ltd

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Pure Chemistry Scientific Inc.

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Shanghai Boc Chemical Co.,Ltd

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Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
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Shanghai Hanhong Scientific Co.,Ltd.

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View Lastest Price from 1-Boc-2-Methylpiperazine manufacturers

Career Henan Chemical Co

Product: 1-Boc-2-Methylpiperazine 120737-78-2
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

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4-N-Boc-3-methylpiperazine

1-Boc-2-Methylpiperazine

2-Methylpiperazine, N1-BOC protected 95%

4-Boc-3-Methyl piperazine

tert-Butyl 2-methylpiperazine-1-carboxylate, 1-(tert-Butoxycarbonyl)-2-methylpiperazine

tert-butyl 2-Methylpiperazin-1-carboxylate

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N-Boc-2-methylpiperazine

120737-78-2

1207378-78-2

pharmacetical

Piperaizine