ChemicalBook > CAS DataBase List > 4-Fluorophenol

4-Fluorophenol

Product Name
4-Fluorophenol
CAS No.
371-41-5
Chemical Name
4-Fluorophenol
Synonyms
Fluorophenol;P-FLUOROPHENOL;FPO;p-Fluorphenol;p-Fluorohenol;4-Fluorphenol;4-FLUOROPHENOL;P-flrorophenol;4-fluoro-pheno;p-fluoro-pheno
CBNumber
CB9672628
Molecular Formula
C6H5FO
Formula Weight
112.1
MOL File
371-41-5.mol
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4-Fluorophenol Property

Melting point:
43-46 °C (lit.)
Boiling point:
185 °C (lit.)
Density 
1.22
Flash point:
155 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
80g/l
form 
Crystalline Solid
pka
9.89(at 25℃)
color 
Yellow-beige to pink
PH
5.4 (H2O, 20℃)(saturated aqueous solution)
Water Solubility 
50 g/L
BRN 
1362752
Stability:
Stable. Flammable. Incompatible with strong oxidizing agents.
Dissociation constant
0 at 27℃
CAS DataBase Reference
371-41-5(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 4-fluoro-(371-41-5)
EPA Substance Registry System
Phenol, 4-fluoro- (371-41-5)
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Safety

Hazard Codes 
Xn,C,T,F+
Risk Statements 
20/21/22-36/37/38-52/53
Safety Statements 
26-37/39-61-36
RIDADR 
UN 2928 6.1/PG 2
WGK Germany 
1
RTECS 
SL4550000
F 
10-23
Hazard Note 
Corrosive/Harmful
TSCA 
T
HazardClass 
6.1
PackingGroup 
III
HS Code 
29081000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F13207
Product name
4-Fluorophenol
Purity
99%
Packaging
25g
Price
$45.7
Updated
2024/03/01
Sigma-Aldrich
Product number
F13207
Product name
4-Fluorophenol
Purity
99%
Packaging
100g
Price
$103
Updated
2024/03/01
TCI Chemical
Product number
F0160
Product name
4-Fluorophenol
Purity
>99.0%(GC)
Packaging
25g
Price
$31
Updated
2024/03/01
TCI Chemical
Product number
F0160
Product name
4-Fluorophenol
Purity
>99.0%(GC)
Packaging
500g
Price
$305
Updated
2024/03/01
Alfa Aesar
Product number
A11945
Product name
4-Fluorophenol, 99%
Packaging
25g
Price
$40.4
Updated
2024/03/01
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4-Fluorophenol Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

4-Fluorophenol is a fluorinated phenolic compound with various applications as a starting reagent for synthesizing pharmaceuticals. It is a widely used intermediate in the industrial production of several drugs, including cisapride and Sabeluzole by Janssen, Sorbinil by Pfizer, and Progabide by Synthelabo.

Definition

ChEBI: 4-fluorophenol is a fluorophenol that is phenol in which the hydrogen para- to the hydroxy group has been replaced by a fluorine. It is a fluorophenol and a member of monofluorobenzenes. It is used as an intermediate in the production of liquid crystals.

Preparation

Acetyl hypofluorite also will fluoro-demetallate benzene derivatives, for example mercury derivatives of phenol gave 4-fluorophenol.

Synthesis Reference(s)

Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8

Hazard

Irritant.

4-Fluorophenol Preparation Products And Raw materials

Raw materials

4-Chloronitrobenzene Hydrogen

Preparation Products

Fluoxetine 3-(4-Fluorophenoxy)propionic acid FLUMICLORAC-PENTYL (4-FLUOROPHENOXY)ACETYL CHLORIDE
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4-Fluorophenol Suppliers

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View Lastest Price from 4-Fluorophenol manufacturers

Huzhou Haipu Chemical Co.,Ltd
Product
4-Fluorophenol 371-41-5
Price
US $1.00/ton
Min. Order
1ton
Purity
99%
Supply Ability
10 tons
Release date
2023-06-30
Hebei Weibang Biotechnology Co., Ltd
Product
4-Fluorophenol 371-41-5
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-05
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Fluorophenol 371-41-5
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-21

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